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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_RS04930 [old locus tag: NWMN_0880 ]
- pan locus tag?: SAUPAN003181000
- symbol: NWMN_RS04930
- pan gene symbol?: cpaA
- synonym:
- product: sodium:proton antiporter
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_RS04930 [old locus tag: NWMN_0880 ]
- symbol: NWMN_RS04930
- product: sodium:proton antiporter
- replicon: chromosome
- strand: +
- coordinates: 974693..976537
- length: 1845
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1801ATGGAGTTTTTATCTTTAGTTATTGTTGTTTTAGCAGCGTTTTTAACTCCAATAATTGTC
AATCGATTAAATATTAATTTCTTGCCAGTTGTTGTTGCAGAAATTTTGATGGGGATTGTG
ATTGGAAATTCATTTCTAAATATAGTAGAAAGGGATTCAATTCTAAATATTTTATCAACG
TTAGGCTTTATCTTTTTAATGTTTTTAAGTGGTTTAGAAATTGATTTTAAAGCTTTTAAA
AAAGATAAACGCGCACGTCAAGGACAAAATGATGATGAATCCTCAATTCCAGGGCATCTT
AATCTAGCGTTAACTGTATTTGCATTTATTATGATTATTTCGATTCTTTTAGCGTATGTA
TTTAAATGGCTTGGATTAGTGGATGATGTGTTATTAATGGTCATTATCATTTCAACTATT
TCCTTAGGCGTAGTTGTTCCAACTTTAAAAGAAATGAATATTATGAGAACAACTATAGGG
CAATTTATCCTATTAGTAGCAGTACTTGCGGACTTAGTAACTATGATTTTATTAACGGTC
TATGGCGCAATCAATGGTCAAGGCGGCAGTACAATATGGTTAATAGGTATATTAGTTGTT
TTCACAGCAATTTCATATATTTTAGGTGTTCAATTTAAAAGAATGTCATTTTTACAAAAA
TTGATGGATGGTACGACGCAAATCGGTATTCGTGCGGTATTTGCATTAATAATATTATTA
GTAGCCCTAGCAGAGGGAGTTGGCGCAGAAAATATATTAGGTGCATTCTTAGCAGGTGTC
GTTGTTTCATTATTAAATCCAGATGAAGAAATGGTTGAAAAGTTAGACTCATTTGGTTAT
GGGTTCTTTATTCCTATTTTCTTTATAATGGTTGGTGTAGATTTAAACATACCTTCATTA
ATTAAAGAACCGAAATTACTAATTATCATACCGATTTTAATCGTTGCATTTATCATTTCA
AAATTAATTCCAGTCATGTTTATTCGACGTTGGTTTGATATGAAAACAACGATTGCATCA
GCATTTTTATTAACATCAACATTATCGCTCGTGATAGCTGCAGCCAAAATTTCAGAAAGA
TTAAATGCTATTTCAGCTGAAACGTCAGGTATATTAATTTTAAGCGCAGTCATTACATGT
GTATTCGTTCCGATTATTTTCAAAAAACTGTTTCCAGTTCCAGATGAGTTTAACCGTAAA
ATTGAAGTTAGTTTAATTGGTAAAAATCAATTAACGATTCCTATAGCGCAAAATTTAACA
TCTCAGTTATATGACGTGACATTATATTATCGCAAAGACTTGAGTGATCGTCGTCAATTG
TCAGATGATATCACGATGATAGAAATTGCTGATTATGAACAAGATGTTTTAGAACGACTA
GGTCTGTTTGACCGAGACATAGTTGTTTGTGCTACGAATGACGATGATATTAACCGAAAA
GTTGCTAAATTAGCCAAAGCACATCAAGTTGAGCGTGTCATTTGCAGACTTGAAAGCACA
ACGGACGATACAGAGTTAGTTGATTCAGGTATTGAAATTTTCAGTAGCTACTTAAGTAAT
AAAATCTTATTAAAAGGTTTAATTGAAACACCTAACATGTTGAATTTATTAAGTAATGTT
GAAACGTCACTATATGAAATTCAAATGTTAAATTATAAATATGAAAATATTCAATTACGT
AATTTCCCATTCGGAGGAGACATCATCTTCGTGCGTATTATCCGTAATAATGAGTCGATT
GTTCCGCATGGAGATACACAATTGCGATATGGAGATCGCTTAATTGTTACCGGTGCTAAA
GAATACGTTGATGAATTGAAGCAAGAGTTAGAATTTTATTTTTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_RS04930 [old locus tag: NWMN_0880 ]
- symbol: NWMN_RS04930
- description: sodium:proton antiporter
- length: 614
- theoretical pI: 4.6983
- theoretical MW: 68677.9
- GRAVY: 0.661075
⊟Function[edit | edit source]
- TIGRFAM: Transport and binding proteins Cations and iron carrying compounds transporter, monovalent cation:proton antiporter-2 (CPA2) family (TIGR00932; HMM-score: 150)
- TheSEED: data available for N315, NCTC8325, USA300_FPR3757
- PFAM: CPA_AT (CL0064) Na_H_Exchanger; Sodium/hydrogen exchanger family (PF00999; HMM-score: 261.6)and 5 moreTrkA_C (CL0582) TrkA_C; TrkA-C domain (PF02080; HMM-score: 37.8)NADP_Rossmann (CL0063) TrkA_N; TrkA-N domain (PF02254; HMM-score: 28)NAD_binding_7; Putative NAD(P)-binding (PF13241; HMM-score: 18.8)NAD_binding_10; NAD(P)H-binding (PF13460; HMM-score: 12.5)DUF166; Domain of unknown function (PF02593; HMM-score: 12)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 12
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.017539
- TAT(Tat/SPI): 0.000195
- LIPO(Sec/SPII): 0.021305
- predicted transmembrane helices (TMHMM): 12
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MEFLSLVIVVLAAFLTPIIVNRLNINFLPVVVAEILMGIVIGNSFLNIVERDSILNILSTLGFIFLMFLSGLEIDFKAFKKDKRARQGQNDDESSIPGHLNLALTVFAFIMIISILLAYVFKWLGLVDDVLLMVIIISTISLGVVVPTLKEMNIMRTTIGQFILLVAVLADLVTMILLTVYGAINGQGGSTIWLIGILVVFTAISYILGVQFKRMSFLQKLMDGTTQIGIRAVFALIILLVALAEGVGAENILGAFLAGVVVSLLNPDEEMVEKLDSFGYGFFIPIFFIMVGVDLNIPSLIKEPKLLIIIPILIVAFIISKLIPVMFIRRWFDMKTTIASAFLLTSTLSLVIAAAKISERLNAISAETSGILILSAVITCVFVPIIFKKLFPVPDEFNRKIEVSLIGKNQLTIPIAQNLTSQLYDVTLYYRKDLSDRRQLSDDITMIEIADYEQDVLERLGLFDRDIVVCATNDDDINRKVAKLAKAHQVERVICRLESTTDDTELVDSGIEIFSSYLSNKILLKGLIETPNMLNLLSNVETSLYEIQMLNYKYENIQLRNFPFGGDIIFVRIIRNNESIVPHGDTQLRYGDRLIVTGAKEYVDELKQELEFYF
⊟Experimental data[edit | edit source]
- experimentally validated: data available for NCTC8325
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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