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FunGene: 08-OCT-2024
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: JSNZ_002519
- pan locus tag?: SAUPAN006197000
- symbol: JSNZ_002519
- pan gene symbol?: cidB
- synonym:
- product: LrgB family protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JSNZ_002519
- symbol: JSNZ_002519
- product: LrgB family protein
- replicon: chromosome
- strand: -
- coordinates: 2525623..2526312
- length: 690
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq:
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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661ATGAATGATTACGTGCAAGCCTTATTAATGATTTTGTTGACTGTCGTTTTATATTATTTC
GCTAAAAGGTTACAACAAAAATATCCGAACCCATTTTTGAATCCAGCATTAATTGCATCT
TTAGGAATTATTTTTGTCTTACTTATCTTTGGAATTAGTTATAACGGGTATATGAAAGGT
GGCAGTTGGATCAACCATATTTTAAACGCAACGGTCGTATGTTTAGCGTACCCACTTTAT
AAAAATAGAGAGAAAATTAAAGACAATGTCTCTATCATTTTTGCAAGTGTATTAACTGGC
GTCATGCTGAATTTCATGTTAGTGTTTTTAACACTTAAAGCATTTGGCTATTCTAAAGAC
GTCATTGTAACATTATTGCCCCGATCTATAACAGCCGCAGTAGGTATCGAAGTGTCACAT
GAACTAGGTGGTACAGATACGATGACTGTACTTTTTATTATCACAACGGGTTTAATCGGT
AGTATTTTAGGTTCGATGTTATTAAGATTTGGAAGATTTGAATCTTCTATCGCCAAAGGT
TTAACGTATGGGAATGCGTCACATGCATTTGGCACAGCTAAAGCACTAGAAATGGATATT
GAATCCGGTGCATTTAGTTCAATTGGGATGATTTTAACTGCAGTTATTAGTTCAGTGTTA
ATACCTGTTCTAATTTTATTATTCTATTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JSNZ_002519
- symbol: JSNZ_002519
- description: LrgB family protein
- length: 229
- theoretical pI: 9.40732
- theoretical MW: 25011.7
- GRAVY: 0.851528
⊟Function[edit | edit source]
- TIGRFAM: Hypothetical proteins Conserved TIGR00659 family protein (TIGR00659; HMM-score: 192.1)
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: CPA_AT (CL0064) LrgB; LrgB-like family (PF04172; HMM-score: 233.5)and 3 moreno clan defined RETICULATA-like; Protein RETICULATA-related (PF11891; HMM-score: 13.4)DUF3290; Protein of unknown function (DUF3290) (PF11694; HMM-score: 12.6)Thioredoxin (CL0172) OST3_OST6; OST3 / OST6 family, transporter family (PF04756; HMM-score: 8.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 6
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0.0002
- Cytoplasmic Membrane Score: 0.9994
- Cell wall & surface Score: 0
- Extracellular Score: 0.0004
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.002069
- TAT(Tat/SPI): 0.000164
- LIPO(Sec/SPII): 0.006048
- predicted transmembrane helices (TMHMM): 6
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
- MNDYVQALLMILLTVVLYYFAKRLQQKYPNPFLNPALIASLGIIFVLLIFGISYNGYMKGGSWINHILNATVVCLAYPLYKNREKIKDNVSIIFASVLTGVMLNFMLVFLTLKAFGYSKDVIVTLLPRSITAAVGIEVSHELGGTDTMTVLFIITTGLIGSILGSMLLRFGRFESSIAKGLTYGNASHAFGTAKALEMDIESGAFSSIGMILTAVISSVLIPVLILLFY
⊟Experimental data[edit | edit source]
- experimentally validated: data available for NCTC8325
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- Operon-mapper [1] : JSNZ_002518 < JSNZ_002519 < cidA
⊟Regulation[edit | edit source]
- regulator: SigB (activation) regulon
SigB (sigma factor) controlling a large regulon involved in stress/starvation response and adaptation; regulation predicted or transferred from N315 and NCTC 8325 in Wolfgramm et al. (https://doi.org/10.1101/2025.09.03.674026) other strains
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
Bioinformatics: 2018, 34(23);4118-4120
[PubMed:29931111] [WorldCat.org] [DOI] (I p)