Jump to navigation
Jump to search
FunGene: 08-OCT-2024
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: JSNZ_002405
- pan locus tag?: SAUPAN005978000
- symbol: gtxA
- pan gene symbol?: —
- synonym:
- product: flippase GtxA
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JSNZ_002405
- symbol: gtxA
- product: flippase GtxA
- replicon: chromosome
- strand: -
- coordinates: 2402729..2403115
- length: 387
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq:
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361ATGAAACTAACACAAACGCATGCTGAAATTTTAAAATTTATCATTGTTGGCGGTATTAAT
ACGTTGAATTATTATGTTGTCTATTTATTGCTGTTAAAATTATTTCACATTGAATATATG
ATTAGTCATATTACCGGATTTATAGTTGCTTTTGTGATTTCTTATTATTTGAATTGTTAT
TTTGTTTACAGAGTAAAACCTACTTGGAGAAAATTTATTAGTTTTCCAATTACGCAGCTT
GTCAACGCAAGCTTACAAACAGTTTTATTATATGTTTTTGTATCCTGGCTAAATTTGCCA
GCGGAAATTGCGCCATTTGCAGGTTTAGTGATTACGATACCCATCACATTTGTATTATCT
AAATGGATTTTAAAAGATAGTAATTAA60
120
180
240
300
360
387
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JSNZ_002405
- symbol: GtxA
- description: flippase GtxA
- length: 128
- theoretical pI: 9.70953
- theoretical MW: 14870.8
- GRAVY: 0.88125
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: no clan defined GtrA_DPMS_TM; GtrA/DPMS, transmembrane domain (PF04138; HMM-score: 94.4)and 3 moreMNHE; Na+/H+ ion antiporter subunit (PF01899; HMM-score: 10.8)DUF4229; Protein of unknown function (DUF4229) (PF14012; HMM-score: 9.6)Syndecan; Syndecan domain (PF01034; HMM-score: 8.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 4
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0.9999
- Cell wall & surface Score: 0
- Extracellular Score: 0.0001
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.000654
- TAT(Tat/SPI): 0.000089
- LIPO(Sec/SPII): 0.01395
- predicted transmembrane helices (TMHMM): 4
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
- MKLTQTHAEILKFIIVGGINTLNYYVVYLLLLKLFHIEYMISHITGFIVAFVISYYLNCYFVYRVKPTWRKFISFPITQLVNASLQTVLLYVFVSWLNLPAEIAPFAGLVITIPITFVLSKWILKDSN
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization: data available for COL
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: SigB (activation) regulon
SigB (sigma factor) controlling a large regulon involved in stress/starvation response and adaptation; regulation predicted or transferred from N315 and NCTC 8325 in Wolfgramm et al. (https://doi.org/10.1101/2025.09.03.674026) other strains
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]