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FunGene: 08-OCT-2024
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: JSNZ_002340
- pan locus tag?: SAUPAN005889000
- symbol: JSNZ_002340
- pan gene symbol?: —
- synonym:
- product: GNAT family N-acetyltransferase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JSNZ_002340
- symbol: JSNZ_002340
- product: GNAT family N-acetyltransferase
- replicon: chromosome
- strand: -
- coordinates: 2338725..2339126
- length: 402
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq:
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361ATGGTTAAAGTGACATATGATATTCCGACTTGCGAGGATTATTGCGCATTAAGGATTAAC
GCAGGTATGAGTCCAAAGACGCACGAAGCAGCTGAAAAAGGATTACCTAATGCCTTATTT
ACAGTAACCTTGTATGATAAAGATCGGTTAATTGGTATGGGTAGAGTAATTGGCGATGGC
GGAACTGTTTTTCAAATTGTTGATATTGCAGTTTTGAAAAGTTACCAAGGTCAAGGTTAC
GGCAGTCTAATTATGGAGCATATTATGCAATATATTAAAGGTGTGGCTGTTGAGAGTACA
TACGTTAGTCTGATTGCAGACTACCCAGCGGATAAATTATATACAAAATTTGGATTTATA
CCTACCGAACCAGATTCAGGCGGTATGTATATCAAATACTAA60
120
180
240
300
360
402
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JSNZ_002340
- symbol: JSNZ_002340
- description: GNAT family N-acetyltransferase
- length: 133
- theoretical pI: 5.11288
- theoretical MW: 14663.9
- GRAVY: 0.0368421
⊟Function[edit | edit source]
- reaction: EC 2.3.1.-? ExPASy
- TIGRFAM: Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 30.4)
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 49.9)Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 48.9)Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 45.8)and 5 moreFR47; FR47-like protein (PF08445; HMM-score: 23.4)GNAT_acetyltr_2; GNAT acetyltransferase 2 (PF13718; HMM-score: 20.2)Acetyltransf_9; Acetyltransferase (GNAT) domain (PF13527; HMM-score: 16.4)IDM1_C; Increased DNA methylation 1, C-terminal (PF23209; HMM-score: 14.3)Acetyltransf_CG; GCN5-related N-acetyl-transferase (PF14542; HMM-score: 13.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9031
- Cytoplasmic Membrane Score: 0.0018
- Cell wall & surface Score: 0.0002
- Extracellular Score: 0.0949
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.011136
- TAT(Tat/SPI): 0.000188
- LIPO(Sec/SPII): 0.0012
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
- MVKVTYDIPTCEDYCALRINAGMSPKTHEAAEKGLPNALFTVTLYDKDRLIGMGRVIGDGGTVFQIVDIAVLKSYQGQGYGSLIMEHIMQYIKGVAVESTYVSLIADYPADKLYTKFGFIPTEPDSGGMYIKY
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- Operon-mapper [1] : JSNZ_002340 < JSNZ_002341 < JSNZ_002342
⊟Regulation[edit | edit source]
- regulator: Fur* (repression) regulon
Fur* (TF) important in Iron homeostasis; regulation predicted or transferred from N315 and NCTC 8325 in Wolfgramm et al. (https://doi.org/10.1101/2025.09.03.674026)
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
Bioinformatics: 2018, 34(23);4118-4120
[PubMed:29931111] [WorldCat.org] [DOI] (I p)