Jump to navigation
Jump to search
FunGene: 08-OCT-2024
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: JSNZ_002275
- pan locus tag?: SAUPAN005785000
- symbol: JSNZ_002275
- pan gene symbol?: —
- synonym:
- product: DUF1641 domain-containing protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JSNZ_002275
- symbol: JSNZ_002275
- product: DUF1641 domain-containing protein
- replicon: chromosome
- strand: -
- coordinates: 2271043..2271516
- length: 474
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq:
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421ATGGCTGAGAGAATATCTTCTAAAATTAGACGCTTAGAAAAATCAGAAGAACAAATTAAG
TTAGAAAGTTTAAATGAAGTTACAGAGGCAATTGCAGCGAATAAAGATAGTATATTAAAA
GCAATCAAGCTTATTAAAACATTAGATGATGCAAAACTATTAGATGCTTTAAATGGTGCA
ATTCGAGGACGTCAAGTCATCATAAATAAATTTGCAGTTGAACTTAATAAAGATATTTAT
ACAGGGCTATTATCTAATATGGCTTCAATGGTGTTTTTATTAGGTGAACTCAATGTATCA
GATTTAAGCGACTTCCTAAATAAAGTTAATAAAGGATTACACGTTGCCAATCAAGCGAGT
CCAAATGCTAAGACAACTATAAGAAGTCTATTGGGCGTATTGAAAGATGACGACATGAAC
CGTAGTTTAACATATATGCTTAATATGCTAAAAGGTATGTCTCGAGAAGATTAA60
120
180
240
300
360
420
474
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JSNZ_002275
- symbol: JSNZ_002275
- description: DUF1641 domain-containing protein
- length: 157
- theoretical pI: 9.49505
- theoretical MW: 17464.2
- GRAVY: -0.158599
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: no clan defined DUF1641; Protein of unknown function (DUF1641) (PF07849; HMM-score: 43.9)and 2 moreRNase_H (CL0219) MGMT_N; Methylated DNA-protein cysteine methyltransferase, N-terminal (PF09153; HMM-score: 13.6)DUF362 (CL0471) Lar_N; Lactate racemase N-terminal domain (PF09861; HMM-score: 12.2)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0.2482
- Cytoplasmic Membrane Score: 0.6826
- Cell wall & surface Score: 0.0026
- Extracellular Score: 0.0666
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.0019
- TAT(Tat/SPI): 0.000231
- LIPO(Sec/SPII): 0.00018
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
- MAERISSKIRRLEKSEEQIKLESLNEVTEAIAANKDSILKAIKLIKTLDDAKLLDALNGAIRGRQVIINKFAVELNKDIYTGLLSNMASMVFLLGELNVSDLSDFLNKVNKGLHVANQASPNAKTTIRSLLGVLKDDDMNRSLTYMLNMLKGMSRED
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- Operon-mapper [1] : JSNZ_002275 < fdhF
⊟Regulation[edit | edit source]
- regulators: Fur* (repression) regulon, SigB (activation) regulon
Fur* (TF) important in Iron homeostasis; regulation predicted or transferred from N315 and NCTC 8325 in Wolfgramm et al. (https://doi.org/10.1101/2025.09.03.674026) SigB (sigma factor) controlling a large regulon involved in stress/starvation response and adaptation; regulation predicted or transferred from N315 and NCTC 8325 in Wolfgramm et al. (https://doi.org/10.1101/2025.09.03.674026) other strains
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
Bioinformatics: 2018, 34(23);4118-4120
[PubMed:29931111] [WorldCat.org] [DOI] (I p)