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⊟Summary[edit | edit source]
- pan ID?: SAUPAN005785000
- symbol?: —
- synonym:
- description?: DUF1641 domain-containing protein
- strand?: -
- coordinates?: 5870376..5870849
- synteny block?: BlockID0045300
- occurrence?: in 100% of 34 strains
forE (yrhD, forE2) : formate oxidoreductase essential subunit [1]
Firmicutes are able to oxidize formate to carbon dioxide and reduce CO2 to bioavailable formate using an atypical molybdopterin-, iron-sulfur cluster- and menaquinone- dependent enzyme. These enzymes are characterized by a catalytic subunit which binds the formyl substrate and an essential subunit that shuttles electrons to or from the menaquinone cofactor. Bacillus encodes two pairs of these recently-discovered enzymes named forCE and forCE2. Staphylococci only contain one version and, unfortunately, they are orthologues of forCE2. Therefore staphylococcal forC and forE are orthologues of Bacillus forC2 and forE2 genes.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_2247 (yrhD)
08BA02176:
C248_2350
11819-97:
MS7_2325
6850:
RSAU_002145
71193:
ST398NM01_2359
ECT-R 2:
ECTR2_2167
ED133:
SAOV_2348c
ED98:
SAAV_2370
HO 5096 0412:
SAEMRSA15_22060
JH1:
SaurJH1_2375
JH9:
SaurJH9_2332
JKD6008:
SAA6008_02343
JKD6159:
SAA6159_02212
JSNZ:
JSNZ_002275
LGA251:
SARLGA251_20910
M013:
M013TW_2265
MRSA252:
SAR2392
MSHR1132:
SAMSHR1132_21330
MSSA476:
SAS2200
Mu3:
SAHV_2292
Mu50:
SAV2308
MW2:
MW2228
RF122:
SAB2185c
ST398:
SAPIG2359
T0131:
SAT0131_02487 (uvrC)
TCH60:
HMPREF0772_10887
TW20:
SATW20_24390
USA300_TCH1516:
USA300HOU_2290
VC40:
SAVC_10400
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MAERISSKIRRLEKSEEQIKLESLNEVTEAIAANKDSILKAIKLIKTLDDAKLLDALNGA
N315 MAERISSKIRRLEKSEEQIKLESLNEVTEAIAANKDSILKAIKLIKTLDDAKLLDALNGA
NCTC8325 MAERISSKIRRLEKSEEQIKLESLNEVTEAIAANKDSILKAIKLIKTLDDAKLLDALNGA
Newman MAERISSKIRRLEKSEEQIKLESLNEVTEAIAANKDSILKAIKLIKTLDDAKLLDALNGA
USA300_FPR3757 MAERISSKIRRLEKSEEQIKLESLNEVTEAIAANKDSILKAIKLIKTLDDAKLLDALNGA
************************************************************
COL IRGRQVIINKFAVELNKDIYTGLLSNMASMVFLLGELNVSDLSDFLNKVNKGLHVANQAS
N315 IRGRQVIINKFAVELNKDIYTGLLSNMASMVFLLGELNVSDLSDFLNKVNKGLHVANQAS
NCTC8325 IRGRQVIINKFAVELNKDIYTGLLSNMASMVFLLGELNVSDLSDFLNKVNKGLHVANQAS
Newman IRGRQVIINKFAVELNKDIYTGLLSNMASMVFLLGELNVSDLSDFLNKVNKGLHVANQAS
USA300_FPR3757 IRGRQVIINKFAVELNKDIYTGLLSNMASMVFLLGELNVSDLSDFLNKVNKGLHVANQAS
************************************************************
COL PNAKTTIRSLLGVLKDDDMNRSLTYMLNMLKGMSREE
N315 PNAKTTIRSLLGVLKDDDMNRSLTYMLNMLKGMSREE
NCTC8325 PNAKTTIRSLLGVLKDDDMNRSLTYMLNMLKGMSREE
Newman PNAKTTIRSLLGVLKDDDMNRSLTYMLNMLKGMSREE
USA300_FPR3757 PNAKTTIRSLLGVLKDDDMNRSLTYMLNMLKGMSREE
*************************************
- ↑ Rodrigo Arias-Cartín, Alexandre Uzel, Farida Seduk, Guillaume Gerbaud, Fabien Pierrel, Marianne Broc, Régine Lebrun, Bruno Guigliarelli, Axel Magalon, Stéphane Grimaldi, Anne Walburger
Identification and characterization of a noncanonical menaquinone-linked formate dehydrogenase.
J Biol Chem: 2022, 298(2);101384
[PubMed:34748728] [WorldCat.org] [DOI] (I p)