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FunGene: 08-OCT-2024
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: JSNZ_002159
- pan locus tag?: SAUPAN005585000
- symbol: lacG
- pan gene symbol?: lacG
- synonym:
- product: 6-phospho-beta-galactosidase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JSNZ_002159
- symbol: lacG
- product: 6-phospho-beta-galactosidase
- replicon: chromosome
- strand: -
- coordinates: 2177445..2178857
- length: 1413
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq:
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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1381ATGACTAAAACATTACCTGAAGATTTTATTTTTGGTGGAGCAACAGCAGCATATCAAGCA
GAAGGTGCGACAAATACGGATGGTAAAGGTCGTGTAGCATGGGATACGTATTTGGAAGAA
AACTATTGGTACACTGCAGAACCAGCGAGTGATTTTTATAACAGATATCCAGTGGATTTA
GAATTAAGTGAAAAATTCGGTGTTAATGGTATCCGTATTTCAATTGCATGGTCACGTATC
TTCCCAAATGGATATGGCGAAGTTAACCCTAAAGGTGTTGAGTATTACCATAAGTTATTT
GCAGAGTGTCATAAACGTCATGTTGAACCATTTGTAACATTGCATCATTTTGATACACCA
GAAGTGTTACACAAAGATGGCGATTTTCTAAATCGTAAAACGATTGACTACTTTGTAGAT
TATGCTGAATATTGTTTTAAAGAGTTCCCAGAAGTAAAATATTGGACTACATTCAATGAA
ATTGGACCTATTGGTGATGGTCAATATTTAGTAGGTAAATTCCCTCCAGGTATTAAATAT
GATTTTGAAAAAGTTTTCCAATCACATCACAATATGATGGTTGCTCATGCAAGAGCAGTA
AAATTATTTAAAGATGGCGGCTATCAAGGAGAAATTGGTGTTGTACACGCATTGCCAACA
AAATATCCGTTCGATCCATCAAATCCTGAAGATGTTCGTGCAGCAGAATTAGAAGATATC
ATCCATAATAAATTCATCTTAGATGCAACATATTTAGGTAAGTATTCTCGTGAAACGATG
GAAGGTGTGCAACATATCTTATCTGTTAATGGCGGTAAATTAAACATTACAGATGAAGAT
TATGCCATTTTAGATGCAGCCAAAGATTTAAACGACTTCTTAGGTATCAATTACTACATG
AGTGATTGGATGAGAGGTTACGATGGAGAATCTGAAATCACGCATAATGCGACAGGTGAT
AAAGGCGGTTCTAAATACCAACTTAAAGGTGTCGGACAACGTGAATTTGATGTCGACGTA
CCTCGCACAGACTGGGACTGGATGATCTATCCTCAAGGTTTATATGATCAAATCATGCGT
GTTGTTAAAGATTATCCTAACTATCATAAGATTTATATCACTGAAAATGGTTTAGGATAT
AAAGATGAATTTATTGAATCTGAAAAAACAGTTCATGATGATGCACGTATTGATTATGTA
AGACAACATTTAAACGTTATTGCAGATGCTATTAAAGATGGTGCAAATGTTAAAGGTTAC
TTTATTTGGTCATTAATGGATGTGTTCTCTTGGTCAAATGGTTATGAAAAACGATATGGT
TTATTCTATGTCGATTTTGAGACTCAAGAACGCTATCCTAAGAAAAGTGCTTATTGGTAC
AAAGAGTTAGCCGAAACAAAAGAAATTAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JSNZ_002159
- symbol: LacG
- description: 6-phospho-beta-galactosidase
- length: 470
- theoretical pI: 4.91432
- theoretical MW: 54564.6
- GRAVY: -0.594468
⊟Function[edit | edit source]
- reaction: EC 3.2.1.85? ExPASy6-phospho-beta-galactosidase A 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol
- TIGRFAM: Energy metabolism Biosynthesis and degradation of polysaccharides 6-phospho-beta-galactosidase (TIGR01233; EC 3.2.1.85; HMM-score: 865.6)and 1 morebeta-galactosidase (TIGR03356; HMM-score: 391.7)
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: TIM_barrel (CL0036) Glyco_hydro_1; Glycosyl hydrolase family 1 (PF00232; HMM-score: 585)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9486
- Cytoplasmic Membrane Score: 0.0002
- Cell wall & surface Score: 0.0003
- Extracellular Score: 0.0508
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.093604
- TAT(Tat/SPI): 0.025265
- LIPO(Sec/SPII): 0.018078
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
- MTKTLPEDFIFGGATAAYQAEGATNTDGKGRVAWDTYLEENYWYTAEPASDFYNRYPVDLELSEKFGVNGIRISIAWSRIFPNGYGEVNPKGVEYYHKLFAECHKRHVEPFVTLHHFDTPEVLHKDGDFLNRKTIDYFVDYAEYCFKEFPEVKYWTTFNEIGPIGDGQYLVGKFPPGIKYDFEKVFQSHHNMMVAHARAVKLFKDGGYQGEIGVVHALPTKYPFDPSNPEDVRAAELEDIIHNKFILDATYLGKYSRETMEGVQHILSVNGGKLNITDEDYAILDAAKDLNDFLGINYYMSDWMRGYDGESEITHNATGDKGGSKYQLKGVGQREFDVDVPRTDWDWMIYPQGLYDQIMRVVKDYPNYHKIYITENGLGYKDEFIESEKTVHDDARIDYVRQHLNVIADAIKDGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERYPKKSAYWYKELAETKEIK
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- Operon-mapper [1] : lacG < JSNZ_002160 < JSNZ_002161 < lacD < lacC < lacB < lacA
⊟Regulation[edit | edit source]
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
Bioinformatics: 2018, 34(23);4118-4120
[PubMed:29931111] [WorldCat.org] [DOI] (I p) - ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
Curr Res Microb Sci: 2025, 9;100489
[PubMed:41146725] [WorldCat.org] [DOI] (I e)