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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002064
  • pan locus tag?: SAUPAN005394000
  • symbol: atpD
  • pan gene symbol?: atpD
  • synonym:
  • product: F0F1 ATP synthase subunit beta

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002064
  • symbol: atpD
  • product: F0F1 ATP synthase subunit beta
  • replicon: chromosome
  • strand: -
  • coordinates: 2077098..2078510
  • length: 1413
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGGAATTGGCCGTGTAACTCAAGTTATGGGTCCTGTAATTGATGTTCGATTTGAACAT
    AACGAAGTTCCTAAAATTAATAACGCCTTGGTTATTGATGTGCCTAAAGAAGAAGGTACA
    ATACAACTAACATTAGAAGTTGCGCTGCAATTAGGTGACGACGTTGTTCGTACAATTGCG
    ATGGATTCAACTGATGGTGTCCAAAGAGGCATGGATGTAAAAGATACAGGCAAAGAAATT
    AGTGTACCTGTTGGTGACGAAACATTAGGTCGTGTATTTAATGTACTAGGTGAAACAATT
    GACCTTAAAGAAGAAATTAGTGATTCTGTTCGCCGCGATCCTATCCATCGTCAAGCACCA
    GCATTCGATGAACTTTCAACAGAAGTTCAAATTTTAGAAACAGGTATTAAAGTAGTAGAT
    TTACTAGCACCTTATATTAAAGGTGGTAAAATCGGATTGTTCGGTGGTGCCGGTGTAGGT
    AAAACAGTATTAATCCAAGAATTAATTAACAACATCGCTCAAGAGCACGGTGGTATTTCT
    GTATTCGCCGGTGTAGGTGAACGTACTCGTGAAGGTAACGATTTATACTTCGAAATGAGT
    GACAGTGGTGTAATTAAGAAAACAGCCATGGTATTCGGGCAAATGAATGAGCCACCTGGT
    GCACGTATGCGTGTTGCATTATCTGGTTTAACAATGGCTGAATATTTCCGTGACGAACAA
    GGTCAAGACGTATTATTATTCATCGATAACATTTTCAGATTTACACAAGCTGGTTCTGAG
    GTATCTGCATTATTAGGTCGTATGCCTTCTGCAGTAGGTTACCAACCAACACTTGCTACT
    GAAATGGGACAATTACAAGAACGTATTACGTCTACAACAAAAGGATCAGTTACTTCTATT
    CAAGCGGTATTCGTACCTGCCGATGACTATACTGACCCAGCGCCTGCGACAGCGTTTGCC
    CATTTAGATGCAACTACTAACTTAGAACGTAAATTAACTGAAATGGGTATTTATCCAGCC
    GTGGATCCATTAGCGTCTACATCAAGAGCATTGGAACCATCAATTGTAGGTCAAGAACAT
    TATGAAGTAGCTCGTGATGTACAATCAACACTTCAAAAATACCGTGAATTGCAAGATATC
    ATTGCTATCTTAGGTATGGACGAATTATCTGATGAAGATAAACAAACAGTTGAACGCGCA
    CGTAGAATTCAATTCTTCTTATCTCAAAACTTCCACGTAGCGGAACAATTTACTGGTCAA
    AAAGGTTCTTATGTACCTGTTAAGACAACAGTTGCAAACTTTAAAGATATCTTAGATGGT
    AAATATGACCATATTCCAGAAGATGCATTCCGTTTAGTTGGTAGCATGGATGATGTTATT
    GCAAAAGCTAAAGATATGGGTGTTGAAGTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1413

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_002064
  • symbol: AtpD
  • description: F0F1 ATP synthase subunit beta
  • length: 470
  • theoretical pI: 4.42228
  • theoretical MW: 51399.9
  • GRAVY: -0.161915

⊟Function[edit | edit source]

  • reaction:
    EC 7.1.2.2?  ExPASy
    non-specified enzyme name
  • TIGRFAM:
    Metabolism Energy metabolism ATP-proton motive force interconversion ATP synthase F1, beta subunit (TIGR01039; EC 3.6.3.14; HMM-score: 844.9)
    and 16 more
    alternate F1F0 ATPase, F1 subunit beta (TIGR03305; EC 3.6.3.-; HMM-score: 586.7)
    Metabolism Energy metabolism ATP-proton motive force interconversion ATPase, FliI/YscN family (TIGR01026; EC 3.6.3.14; HMM-score: 234.1)
    Cellular processes Cellular processes Pathogenesis type III secretion apparatus H+-transporting two-sector ATPase (TIGR02546; EC 3.6.3.14; HMM-score: 233.1)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type III secretion apparatus H+-transporting two-sector ATPase (TIGR02546; EC 3.6.3.14; HMM-score: 233.1)
    Cellular processes Cellular processes Chemotaxis and motility flagellar protein export ATPase FliI (TIGR03496; EC 3.6.3.14; HMM-score: 229.2)
    flagellar protein export ATPase FliI (TIGR03498; EC 3.6.3.14; HMM-score: 226.1)
    Cellular processes Cellular processes Chemotaxis and motility flagellar protein export ATPase FliI (TIGR03497; EC 3.6.3.14; HMM-score: 216)
    Metabolism Energy metabolism ATP-proton motive force interconversion ATP synthase archaeal, B subunit (TIGR01041; EC 3.6.3.14; HMM-score: 143.4)
    Metabolism Energy metabolism ATP-proton motive force interconversion ATP synthase archaeal, A subunit (TIGR01043; EC 3.6.3.14; HMM-score: 134.6)
    alternate F1F0 ATPase, F1 subunit alpha (TIGR03324; EC 3.6.3.-; HMM-score: 133.2)
    Metabolism Energy metabolism ATP-proton motive force interconversion ATP synthase F1, alpha subunit (TIGR00962; EC 3.6.3.14; HMM-score: 132.4)
    Metabolism Transport and binding proteins Cations and iron carrying compounds V-type ATPase, A subunit (TIGR01042; EC 3.6.3.14; HMM-score: 121.4)
    Metabolism Transport and binding proteins Cations and iron carrying compounds V-type ATPase, B subunit (TIGR01040; EC 3.6.3.14; HMM-score: 103)
    Genetic information processing Transcription Transcription factors transcription termination factor Rho (TIGR00767; EC 3.6.4.-; HMM-score: 41.1)
    Genetic information processing Protein synthesis Translation factors ribosome small subunit-dependent GTPase A (TIGR00157; EC 3.6.-.-; HMM-score: 13)
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase Rlu family protein, TIGR01621 (TIGR01621; EC 5.4.99.-; HMM-score: 11.9)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    P-loop_NTPase (CL0023) ATP-synt_ab; ATP synthase alpha/beta family, nucleotide-binding domain (PF00006; HMM-score: 248.3)
    and 18 more
    ALR_C-like (CL0866) ATP-synt_ab_N; ATP synthase alpha/beta family, beta-barrel domain (PF02874; HMM-score: 70.3)
    no clan defined ATP-synt_VA_C; C-terminal domain of V and A type ATP synthase (PF22919; HMM-score: 64.3)
    P-loop_NTPase (CL0023) RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 23.5)
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 17.5)
    ATPase_2; ATPase domain predominantly from Archaea (PF01637; HMM-score: 17.4)
    AAA_16; AAA ATPase domain (PF13191; HMM-score: 16.3)
    ABC_tran; ABC transporter (PF00005; HMM-score: 15.7)
    NB-ARC; NB-ARC domain (PF00931; HMM-score: 15.2)
    AAA_22; AAA domain (PF13401; HMM-score: 15)
    no clan defined T3SS_ATPase_C; T3SS EscN ATPase C-terminal domain (PF18269; HMM-score: 14.8)
    P-loop_NTPase (CL0023) NACHT; NACHT domain (PF05729; HMM-score: 14)
    AAA_19; AAA domain (PF13245; HMM-score: 13.9)
    AAA_14; AAA domain (PF13173; HMM-score: 13.2)
    RNA_helicase; RNA helicase (PF00910; HMM-score: 13.1)
    AAA_25; AAA domain (PF13481; HMM-score: 12.6)
    TrwB_AAD_bind; Type IV secretion-system coupling protein DNA-binding domain (PF10412; HMM-score: 12.3)
    AAA_7; P-loop containing dynein motor region (PF12775; HMM-score: 12.3)
    ATPase; KaiC (PF06745; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.4735
    • Cytoplasmic Membrane Score: 0.4054
    • Cell wall & surface Score: 0.0007
    • Extracellular Score: 0.1204
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003037
    • TAT(Tat/SPI): 0.000134
    • LIPO(Sec/SPII): 0.000342
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MGIGRVTQVMGPVIDVRFEHNEVPKINNALVIDVPKEEGTIQLTLEVALQLGDDVVRTIAMDSTDGVQRGMDVKDTGKEISVPVGDETLGRVFNVLGETIDLKEEISDSVRRDPIHRQAPAFDELSTEVQILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYFEMSDSGVIKKTAMVFGQMNEPPGARMRVALSGLTMAEYFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTTKGSVTSIQAVFVPADDYTDPAPATAFAHLDATTNLERKLTEMGIYPAVDPLASTSRALEPSIVGQEHYEVARDVQSTLQKYRELQDIIAILGMDELSDEDKQTVERARRIQFFLSQNFHVAEQFTGQKGSYVPVKTTVANFKDILDGKYDHIPEDAFRLVGSMDDVIAKAKDMGVEV

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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