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⊟Summary[edit | edit source]
- pan ID?: SAUPAN005394000
- symbol?: atpD
- synonym:
- description?: F0F1 ATP synthase subunit beta
- F0F1 ATP synthase subunit beta
- ATP synthase subunit beta
- ATP synthase F0F1 subunit beta
- FOF1-ATP synthase, subunit beta
- ATP synthase beta chain
- ATP synthase F1, beta subunit
- ATP synthase F1 sector beta subunit
- ATP synthase F1 subunit beta
- ATP synthase subunit beta, AtpB
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 5556044..5557456
- synteny block?: BlockID0041900
- occurrence?: in 100% of 34 strains
atpD : F0F1 ATP synthase subunit beta [1]
ATP synthases couple proton translocation across membranes to rotational energy, conformational change and, ultimately, ATP generation. The F0 portion is a multimeric membrane-embedded proton channel (ab2c10) while the F1 portion is a multimeric cytoplasmic structure (α3β3γδε) that binds ADP and phosphate. When necessary, this process can also be run in reverse to generate a proton gradient at the expense of ATP. AtpD encodes F1 subunit β, the catalytic component of the α3β3 trimer-of-heterodimers "pinwheel". Based on its rotational positioning, the β component of the αβ dimer can bind ADP+Pi substrates, condense substrates into ATP or release the ATP product.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_2043 (atpD)
08BA02176:
C248_2117 (atpD)
11819-97:
MS7_2119 (atpD)
6850:
RSAU_001941 (atpD)
71193:
ST398NM01_2145
ECT-R 2:
ECTR2_1959 (atpD)
ED133:
SAOV_2144c
ED98:
SAAV_2158 (atpD)
HO 5096 0412:
SAEMRSA15_20110 (atpD)
JH1:
SaurJH1_2177
JH9:
SaurJH9_2139
JKD6008:
SAA6008_02141 (atpB)
JKD6159:
SAA6159_02017 (atpB)
JSNZ:
JSNZ_002064 (atpD)
LGA251:
SARLGA251_19040 (atpD)
M013:
M013TW_2062
MRSA252:
SAR2191 (atpD)
MSHR1132:
SAMSHR1132_19260
MSSA476:
SAS2006
Mu3:
SAHV_2087 (atpD)
Mu50:
SAV2103 (atpD)
MW2:
MW2027 (atpD)
RF122:
SAB1987c (atpD)
ST398:
SAPIG2145 (atpD)
T0131:
SAT0131_02264
TCH60:
HMPREF0772_11088 (atpD)
TW20:
SATW20_22410 (atpD)
USA300_TCH1516:
USA300HOU_2093 (atpD)
VC40:
SAVC_09390
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MGIGRVTQVMGPVIDVRFEHNEVPKINNALVIDVPKEEGTIQLTLEVALQLGDDVVRTIA
N315 MGIGRVTQVMGPVIDVRFEHNEVPKINNALVIDVPKEEGTIQLTLEVALQLGDDVVRTIA
NCTC8325 MGIGRVTQVMGPVIDVRFEHNEVPKINNALVIDVPKEEGTIQLTLEVALQLGDDVVRTIA
Newman MGIGRVTQVMGPVIDVRFEHNEVPKINNALVIDVPKEEGTIQLTLEVALQLGDDVVRTIA
USA300_FPR3757 MGIGRVTQVMGPVIDVRFEHNEVPKINNALVIDVPKEEGTIQLTLEVALQLGDDVVRTIA
************************************************************
COL MDSTDGVQRGMDVKDTGKEISVPVGDETLGRVFNVLGETIDLKEEISDSVRRDPIHRQAP
N315 MDSTDGVQRGMDVKDTGKEISVPVGDETLGRVFNVLGETIDLKEEISDSVRRDPIHRQAP
NCTC8325 MDSTDGVQRGMDVKDTGKEISVPVGDETLGRVFNVLGETIDLKEEISDSVRRDPIHRQAP
Newman MDSTDGVQRGMDVKDTGKEISVPVGDETLGRVFNVLGETIDLKEEISDSVRRDPIHRQAP
USA300_FPR3757 MDSTDGVQRGMDVKDTGKEISVPVGDETLGRVFNVLGETIDLKEEISDSVRRDPIHRQAP
************************************************************
COL AFDELSTEVQILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGIS
N315 AFDELSTEVQILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGIS
NCTC8325 AFDELSTEVQILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGIS
Newman AFDELSTEVQILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGIS
USA300_FPR3757 AFDELSTEVQILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGIS
************************************************************
COL VFAGVGERTREGNDLYFEMSDSGVIKKTAMVFGQMNEPPGARMRVALSGLTMAEYFRDEQ
N315 VFAGVGERTREGNDLYFEMSDSGVIKKTAMVFGQMNEPPGARMRVALSGLTMAEYFRDEQ
NCTC8325 VFAGVGERTREGNDLYFEMSDSGVIKKTAMVFGQMNEPPGARMRVALSGLTMAEYFRDEQ
Newman VFAGVGERTREGNDLYFEMSDSGVIKKTAMVFGQMNEPPGARMRVALSGLTMAEYFRDEQ
USA300_FPR3757 VFAGVGERTREGNDLYFEMSDSGVIKKTAMVFGQMNEPPGARMRVALSGLTMAEYFRDEQ
************************************************************
COL GQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTTKGSVTSI
N315 GQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTTKGSVTSI
NCTC8325 GQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTTKGSVTSI
Newman GQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTTKGSVTSI
USA300_FPR3757 GQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTTKGSVTSI
************************************************************
COL QAVFVPADDYTDPAPATAFAHLDATTNLERKLTEMGIYPAVDPLASTSRALEPSIVGQEH
N315 QAVFVPADDYTDPAPATAFAHLDATTNLERKLTEMGIYPAVDPLASTSRALEPSIVGQEH
NCTC8325 QAVFVPADDYTDPAPATAFAHLDATTNLERKLTEMGIYPAVDPLASTSRALEPSIVGQEH
Newman QAVFVPADDYTDPAPATAFAHLDATTNLERKLTEMGIYPAVDPLASTSRALEPSIVGQEH
USA300_FPR3757 QAVFVPADDYTDPAPATAFAHLDATTNLERKLTEMGIYPAVDPLASTSRALEPSIVGQEH
************************************************************
COL YEVARDVQSTLQKYRELQDIIAILGMDELSDEDKQTVERARRIQFFLSQNFHVAEQFTGQ
N315 YEVARDVQSTLQKYRELQDIIAILGMDELSDEDKQTVERARRIQFFLSQNFHVAEQFTGQ
NCTC8325 YEVARDVQSTLQKYRELQDIIAILGMDELSDEDKQTVERARRIQFFLSQNFHVAEQFTGQ
Newman YEVARDVQSTLQKYRELQDIIAILGMDELSDEDKQTVERARRIQFFLSQNFHVAEQFTGQ
USA300_FPR3757 YEVARDVQSTLQKYRELQDIIAILGMDELSDEDKQTVERARRIQFFLSQNFHVAEQFTGQ
************************************************************
COL KGSYVPVKTTVANFKDILDGKYDHIPEDAFRLVGSMDDVIAKAKDMGVEV
N315 KGSYVPVKTTVANFKDILDGKYDHIPEDAFRLVGSMDDVIAKAKDMGVEV
NCTC8325 KGSYVPVKTTVANFKDILDGKYDHIPEDAFRLVGSMDDVIAKAKDMGVEV
Newman KGSYVPVKTTVANFKDILDGKYDHIPEDAFRLVGSMDDVIAKAKDMGVEV
USA300_FPR3757 KGSYVPVKTTVANFKDILDGKYDHIPEDAFRLVGSMDDVIAKAKDMGVEV
**************************************************
- ↑ G Deckers-Hebestreit, K Altendorf
The F0F1-type ATP synthases of bacteria: structure and function of the F0 complex.
Annu Rev Microbiol: 1996, 50;791-824
[PubMed:8905099] [WorldCat.org] [DOI] (P p)Martin Vestergaard, Sahar Roshanak, Hanne Ingmer
Targeting the ATP Synthase in Staphylococcus aureus Small Colony Variants, Streptococcus pyogenes and Pathogenic Fungi.
Antibiotics (Basel): 2021, 10(4);
[PubMed:33918382] [WorldCat.org] [DOI] (P e)