PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

FunGene: 08-OCT-2024

⊟Summary

• organism: Staphylococcus aureus JSNZ
• locus tag: JSNZ_001744
• pan locus tag^?: SAUPAN004432000
• symbol: JSNZ_001744
• pan gene symbol^?: —
• synonym:
• product: polysaccharide biosynthesis C-terminal domain-containing protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: JSNZ_001744
• symbol: JSNZ_001744
• product: polysaccharide biosynthesis C-terminal domain-containing protein
• replicon: chromosome
• strand: -
• coordinates: 1790315..1791976
• length: 1662
• essential: unknown other strains

⊟Accession numbers

• Gene ID:
• RefSeq:
• BioCyc:
• MicrobesOnline:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  1261
  1321
  1381
  1441
  1501
  1561
  1621
  
  ATGAGTGAAAGTAAAGAAATGGTGCGTGGAACCTTTTTAATTACCATTAGTATATTAATT
  ACCAAGGTATTGGGCGTACTTTTTATCATTCCATTCAACTATTTAATTGGTGGACAAGAA
  AATATGGCGCCGTTCACATACGCTTATGCACCATATAATATTGCAATTGCAGTTGCGACA
  GCAGGTGTACCATTAGCAGCTTCGAAATATGTTGCGAAATATAATGCTATTGGGGCATAT
  AAAGTCAGTCAGAAATTTTATAAATCGAGTTTTATTGTAATGAGTATTACCGGTGTTTTA
  GGTTTCTTGGTACTGTATTTCCTAGCACCTTATATTTCTGAATTAACATTAGCTAGAAAC
  GTTCATGATAAAAACGGTTGGTCAGTCGATGATATTACTTGGATTATAAGAATCATTAGT
  ATGGTTGTTATCTTTATTCCTGTATTAGCGACATGGAGAGGTATATTCCAAGGTTATAAA
  TATATGGGGCCAACAGCAGTGTCAGAAGTAACTGAGCAAATTGCACGCGTGATTTTCATA
  TTAATCGGAAGTTATTTAGTACTAAATGTCTTTGATGGCTCTATTTTATTAGCCAATGGT
  ATTGCTACTTTTGCAGCAGCAGTTGGTGCGATTATTGGTATATTCACACTCTGGTATTAC
  TGGAGAAAGCGTAAGCATAATATTGATCGTATGGTCGAATCTGATTACACAGATATAGAT
  GTGTCATATGGCAAGATGTATAAAGAAATTATTGCTTATAGTATTCCGTTCGTTATTGTA
  AGTTTGAATTATCCATTATTTAACTTAGTAGATCAATTTACACATAACGGTGCTTTATCT
  TTAGTTGGTATACCTTCACAGTTACAAGATATATTCTTTAATATGCTAAATATGTCAACT
  AATAAAATTGTAATGATTCCGACATCATTAAGTGCTGGTTTTGCAGTGAGTTTAATTCCT
  TTTATTACAAAAACATTTGCAGAAGGTCGCTTACATGAAATGCATCATCAAATTAGAACA
  TCTATTGGTGTATTAATGTTTATAACTGTTCCAGCTAGTATTGGAATTATGGCCTTGGCA
  CAACCATTATTCACAGTTTTCTATGGTTACGATCCAATTGTTTTAGGTCATGACCCTAAC
  CATGATGGTAGTCGCTTATTATTCTATTATGCGCCTGTAGCAATACTAATTTCACTATTA
  AGTGTAACGGCATCAATGTTACAAGGTATAGATAAACAGAAATTAACAGTTTATGTTATT
  TTAGCTTCTGTAGTTATCAAGTTAGCGTTAAACTATCCATTAATTATGTTATTCCATACA
  CCTGGTGCAATTTTAAGTACTAGTATCGCATTATTATTTGCAATTGGATGTAATTTCTAT
  ATTCTTAAAAAATATGCGAAGTTTAAATTCAGCTATAGTTGGATTCATTTTGCAAAAATA
  TTCTTGTATTCATTTATTATGATGCTAGGTGTAGAATTAGTATTCATCCTTGCAAATCTA
  TTCTTAGAACCTACTAAACTTGGTTACTTAATCATTATTATTTTAGGTGTTACAGTAGGT
  ATTCTAATTTACGGTACAATCACAATTAAAACGCGTCTTGCGGACGAATTCTTAGGTGAA
  ATTCCTGAAAAATTAAGACGTAGAGTTAGGTTTTTACGATGA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  1020
  1080
  1140
  1200
  1260
  1320
  1380
  1440
  1500
  1560
  1620
  1662
  

⊟Protein

⊟General

• locus tag: JSNZ_001744
• symbol: JSNZ_001744
• description: polysaccharide biosynthesis C-terminal domain-containing protein
• length: 553
• theoretical pI: 9.70447
• theoretical MW: 61957.4
• GRAVY: 0.721157

⊟Function

• TIGRFAM:
  Cellular processes Cellular processes Sporulation and germination stage V sporulation protein B (TIGR02900; HMM-score: 120.8)
  and 2 more
  Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan murein biosynthesis integral membrane protein MurJ (TIGR01695; HMM-score: 41.5)
  Metabolism Transport and binding proteins Other MATE efflux family protein (TIGR00797; HMM-score: 22.3)
• TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
• PFAM:
  MviN_MATE (CL0222) Polysacc_synt; Polysaccharide biosynthesis protein (PF01943; HMM-score: 83.1)
  and 5 more
  MatE; MatE (PF01554; HMM-score: 40.7)
  MurJ; Lipid II flippase MurJ (PF03023; HMM-score: 34.4)
  BPD_transp_1 (CL0404) FtsX; FtsX-like permease C-terminal (PF02687; HMM-score: 14.9)
  no clan defined Phage_holin_10; Bacteriophage holin Pam3 gp28 family (PF23987; HMM-score: 13.8)
  Kinocilin; Kinocilin protein (PF15033; HMM-score: 6.9)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 14
• DeepLocPro: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 0.9999
  • Cell wall & surface Score: 0
  • Extracellular Score: 0
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.043737
  • TAT(Tat/SPI): 0.000861
  • LIPO(Sec/SPII): 0.002372
• predicted transmembrane helices (TMHMM): 14

⊟Accession numbers

• GI:
• RefSeq:
• UniProt:

⊟Protein sequence

• MSESKEMVRGTFLITISILITKVLGVLFIIPFNYLIGGQENMAPFTYAYAPYNIAIAVATAGVPLAASKYVAKYNAIGAYKVSQKFYKSSFIVMSITGVLGFLVLYFLAPYISELTLARNVHDKNGWSVDDITWIIRIISMVVIFIPVLATWRGIFQGYKYMGPTAVSEVTEQIARVIFILIGSYLVLNVFDGSILLANGIATFAAAVGAIIGIFTLWYYWRKRKHNIDRMVESDYTDIDVSYGKMYKEIIAYSIPFVIVSLNYPLFNLVDQFTHNGALSLVGIPSQLQDIFFNMLNMSTNKIVMIPTSLSAGFAVSLIPFITKTFAEGRLHEMHHQIRTSIGVLMFITVPASIGIMALAQPLFTVFYGYDPIVLGHDPNHDGSRLLFYYAPVAILISLLSVTASMLQGIDKQKLTVYVILASVVIKLALNYPLIMLFHTPGAILSTSIALLFAIGCNFYILKKYAKFKFSYSWIHFAKIFLYSFIMMLGVELVFILANLFLEPTKLGYLIIIILGVTVGILIYGTITIKTRLADEFLGEIPEKLRRRVRFLR

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications