From AureoWiki
Jump to navigation Jump to search

FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001348
  • pan locus tag?: SAUPAN003757000
  • symbol: JSNZ_001348
  • pan gene symbol?: umuC
  • synonym:
  • product: Y-family DNA polymerase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001348
  • symbol: JSNZ_001348
  • product: Y-family DNA polymerase
  • replicon: chromosome
  • strand: +
  • coordinates: 1362066..1363328
  • length: 1263
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    GTGTATAATTATCATTTATTAGAAGATAGGGATGTTCTATGTATTGACCAAAAAAGTTTT
    TTTGCGAGTGTTTCTTGTATTGAAAAGGGGCTAGATCCATTAGAAACAAAGTTAGCTGTT
    GTTGCAGATACTAAGCGTCAGGGTTCTGTAATATTGGCTGCGACACCTAAATTAAAAGAA
    TTAGGCATCAAGACAGGGTCGCGATTGTTTGAAATACCACATAGAAATGATATTTACATT
    ATCAATCCAAGTATGCGTAAATATCTTAATGTTTCAGTTGCTATTTCTAAGATTGCATTG
    CGTTATATTCCACCTGAAGATTTACACCAATATAGTATTGACGAATTTTTTATGGATGTT
    ACTGATAGCTATCATAGATTTAGTTCTACAGTACATGCATTTTGCGAAAGACTTAAACGT
    GAAATTTATGAAGAAACAGGCATTTATTGTACTGTGGGCATTGGTTCTAATATGTTATTA
    AGTAAAATTGCTATGGATGTTGAAGCGAAGCATAGTCAAAATGGTATAGCTGAATGGCGA
    TATCAAGATGTACCAACGAAATTATGGCCAATTCAGCCCTTGCGAGATTTTTGGGGTATT
    AATCGTCGAACAGAAGCCAAATTGAATAAAAGAGGAATTTTTACTATAGGAGATTTAGCG
    AAATATCCATATAAATTTTTAAAAAAAGAGTTCGGTATTTTAGGTGTTGATATGCATCTA
    CATGCGAATGGGATAGATCAGAGTAAAGTACGTGAAAAGCACAAGATCAGCAATCCATCG
    ATATGCAAAAGTCAAATATTAATGAGAGATTATCATTTTGATGAAGCAAAAGTAGTAATG
    CAAGAGTTAATTGAAGATGTTGCTAGCAGAGTTCGAGCAAGAAAAAAAGTGGCAAGAACG
    ATACATTTTGCCTTTGGCTATAGTGATGAAGGCGGTGTACATAAGCAATATACTTTGAAA
    GATCCAACAAACTTAGAAAAAGATATTTATAAAGTAGTAATGCATTTTGCAGATAAATTA
    TGTAATAAACAAGCACTATATCGTACGCTAAGTATATCTTTGAGTCAATTTATTAATGAG
    GATGAGCGACAGTTAAGTCTGTTTGAAGATGAATACCAACGCAAACGTGACGAATGCCTA
    GCTAAAACGATAGACCAATTACATTTGAAATACGGCAAAGGTATTGTGTCCAAAGCAGTA
    TCGTTTACAGAAGCAGGTACAAAACATGGTAGATTAGGTTTAATGGCTGGACATAAAATG
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1263

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001348
  • symbol: JSNZ_001348
  • description: Y-family DNA polymerase
  • length: 420
  • theoretical pI: 9.23261
  • theoretical MW: 48426.6
  • GRAVY: -0.393571

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    no clan defined IMS; impB/mucB/samB family (PF00817; HMM-score: 125.3)
    and 3 more
    IMS_C; impB/mucB/samB family C-terminal domain (PF11799; HMM-score: 66.1)
    HHH (CL0198) IMS_HHH; IMS family HHH motif (PF11798; HMM-score: 37.6)
    IMS_HHH_1; DNA polymerase-iota, thumb domain (PF21999; HMM-score: 32.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9792
    • Cytoplasmic Membrane Score: 0.011
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0096
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004875
    • TAT(Tat/SPI): 0.002363
    • LIPO(Sec/SPII): 0.013254
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MYNYHLLEDRDVLCIDQKSFFASVSCIEKGLDPLETKLAVVADTKRQGSVILAATPKLKELGIKTGSRLFEIPHRNDIYIINPSMRKYLNVSVAISKIALRYIPPEDLHQYSIDEFFMDVTDSYHRFSSTVHAFCERLKREIYEETGIYCTVGIGSNMLLSKIAMDVEAKHSQNGIAEWRYQDVPTKLWPIQPLRDFWGINRRTEAKLNKRGIFTIGDLAKYPYKFLKKEFGILGVDMHLHANGIDQSKVREKHKISNPSICKSQILMRDYHFDEAKVVMQELIEDVASRVRARKKVARTIHFAFGYSDEGGVHKQYTLKDPTNLEKDIYKVVMHFADKLCNKQALYRTLSISLSQFINEDERQLSLFEDEYQRKRDECLAKTIDQLHLKYGKGIVSKAVSFTEAGTKHGRLGLMAGHKM

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: LexA (repression) regulon
    LexA(TF)important in SOS response;  regulation predicted or transferred from N315 and NCTC 8325  [1]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

Retrieved from "http://fungenwikiserver.biologie.uni-greifswald.de/aureowiki/index.php?title=JSNZ_001348&oldid=106989"