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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001247
  • pan locus tag?: SAUPAN003576000
  • symbol: JSNZ_001247
  • pan gene symbol?: rnjB
  • synonym:
  • product: ribonuclease J

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001247
  • symbol: JSNZ_001247
  • product: ribonuclease J
  • replicon: chromosome
  • strand: +
  • coordinates: 1259018..1260691
  • length: 1674
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    TTGAGTTTAATAAAGAAAAAGAATAAAGATATTCGCATTATACCATTAGGCGGTGTTGGC
    GAAATTGCTAAAAATATGTATATCGTTGAAGTAGACGATGAAATGTTTATGTTAGATGCT
    GGACTTATGTTTCCAGAAGACGAAATGCTAGGTATTGATATTGTTATACCAGACATTTCA
    TACGTACTTGAAAATAAAGATAAATTGAAGGGTATATTCCTTACACACGGACATGAGCAT
    GCGATTGGTGCAGTGAGTTATGTTTTAGAACAATTAGATGCACCAGTATATGGATCTAAA
    TTGACAATAGCGTTAATTAAAGAAAATATGAAAGCCCGTAATATTGATAAAAAAGTTCGC
    TACTACACAGTTAATAATGATTCAATTATGAGATTCAAAAACGTGAATATTAGTTTCTTT
    AATACGACACACAGTATTCCTGATAGTCTAGGTGTTTGTATTCATACTTCATATGGTGCC
    ATTGTGTATACAGGTGAATTTAAGTTTGACCAAAGTTTACATGGACATTATGCACCAGAT
    ATTAAACGTATGGCAGAGATTGGTGAAGAAGGCGTATTTGTCTTAATCAGTGATTCTACT
    GAGGCAGAGAAACCTGGATATAATACTCCGGAAAATGTGATTGAACATCATATGTATGAC
    GCTTTTGCAAAAGTGCGAGGTCGCTTGATTGTTTCATGTTATGCTTCGAACTTTATACGT
    ATACAGCAAGTTTTAAATATTGCTAGCAAGCTAAATCGTAAAGTGTCATTTTTAGGAAGA
    TCACTTGAAAGTTCATTTAATATTGCTCGTAAAATGGGGTATTTCGACATTCCTAAAGAT
    TTGCTAATTCCTATAACAGAAGTTGATAATTATCCTAAAAATGAAGTGATAATTATAGCT
    ACTGGTATGCAAGGAGAACCTGTAGAAGCCTTAAGTCAAATGGCGCAACATAAGCATAAA
    ATTATGAATATCGAAGAAGGCGATTCTGTATTTTTAGCAATTACGGCTTCTGCAAATATG
    GAAGTTATCATTGCGAATACATTAAATGAGCTTGTACGTGCTGGCGCACATATTATTCCA
    AATAACAAGAAGATTCATGCTTCAAGTCATGGTTGCATGGAAGAATTAAAAATGATGATT
    AATATTATGAAACCTGAATACTTTATTCCTGTACAAGGTGAATTTAAAATGCAGATAGCA
    CATGCGAAGCTAGCAGCTGAAGCAGGTGTTGCACCAGAAAAGATTTTCCTTGTGGAAAAA
    GGAGATGTCATTAATTACAACGGTAAAGATATGATATTAAATGAAAAGGTAAATTCAGGA
    AATATTTTAATAGATGGTATTGGTATTGGGGATGTAGGAAATATCGTGTTGAGAGACCGT
    CATCTTTTAGCAGAAGATGGTATCTTTATTGCTGTAGTAACGTTAGATCCTAAAAATAGA
    CGTATAGCTGCGGGACCTGAAATTCAATCTCGTGGGTTTGTATATGTACGTGAAAGTGAA
    GACTTATTACGTGAAGCAGAAGAGAAGGTACGTGAAATAGTAGAGGCTGGTTTACAAGAA
    AAACGCATAGAATGGTCTGAAATTAAGCAAAATATGCGTGATCAAATTAGTAAACTATTA
    TTCGAAAGTACAAAACGTCGTCCTATGATTATTCCAGTAATTTCTGAAATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1674

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001247
  • symbol: JSNZ_001247
  • description: ribonuclease J
  • length: 557
  • theoretical pI: 6.10952
  • theoretical MW: 62603.1
  • GRAVY: -0.0983842

⊟Function[edit | edit source]

  • reaction:
    EC 3.1.-.-?  ExPASy
  • TIGRFAM:
    Genetic information processing Transcription Degradation of RNA beta-CASP ribonuclease, RNase J family (TIGR00649; EC 3.1.-.-; HMM-score: 606)
    and 2 more
    arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein (TIGR03675; HMM-score: 26.3)
    Cellular processes Cellular processes Detoxification hydroxyacylglutathione hydrolase (TIGR03413; EC 3.1.2.6; HMM-score: 16.9)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    no clan defined RNase_J_b_CASP; Ribonuclease J, beta-CASP domain (PF22505; HMM-score: 118.4)
    RNase_J_C; Ribonuclease J C-terminal domain (PF17770; HMM-score: 111.7)
    and 5 more
    RMMBL_DRMBL (CL0398) RMMBL; Zn-dependent metallo-hydrolase RNA specificity domain (PF07521; HMM-score: 48.4)
    Metallo-HOrase (CL0381) Lactamase_B; Metallo-beta-lactamase superfamily (PF00753; HMM-score: 28.5)
    Lactamase_B_2; Beta-lactamase superfamily domain (PF12706; HMM-score: 24.8)
    ATP_synthase (CL0255) vATP-synt_E; ATP synthase (E/31 kDa) subunit (PF01991; HMM-score: 15.2)
    HTH (CL0123) HTH_10; HTH DNA binding domain (PF04967; HMM-score: 13.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8421
    • Cytoplasmic Membrane Score: 0.09
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0676
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001198
    • TAT(Tat/SPI): 0.000054
    • LIPO(Sec/SPII): 0.000176
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSLIKKKNKDIRIIPLGGVGEIAKNMYIVEVDDEMFMLDAGLMFPEDEMLGIDIVIPDISYVLENKDKLKGIFLTHGHEHAIGAVSYVLEQLDAPVYGSKLTIALIKENMKARNIDKKVRYYTVNNDSIMRFKNVNISFFNTTHSIPDSLGVCIHTSYGAIVYTGEFKFDQSLHGHYAPDIKRMAEIGEEGVFVLISDSTEAEKPGYNTPENVIEHHMYDAFAKVRGRLIVSCYASNFIRIQQVLNIASKLNRKVSFLGRSLESSFNIARKMGYFDIPKDLLIPITEVDNYPKNEVIIIATGMQGEPVEALSQMAQHKHKIMNIEEGDSVFLAITASANMEVIIANTLNELVRAGAHIIPNNKKIHASSHGCMEELKMMINIMKPEYFIPVQGEFKMQIAHAKLAAEAGVAPEKIFLVEKGDVINYNGKDMILNEKVNSGNILIDGIGIGDVGNIVLRDRHLLAEDGIFIAVVTLDPKNRRIAAGPEIQSRGFVYVRESEDLLREAEEKVREIVEAGLQEKRIEWSEIKQNMRDQISKLLFESTKRRPMIIPVISEI

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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