PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

FunGene: 08-OCT-2024

⊟Summary

• organism: Staphylococcus aureus JSNZ
• locus tag: JSNZ_001153
• pan locus tag^?: SAUPAN003454000
• symbol: JSNZ_001153
• pan gene symbol^?: divIB
• synonym:
• product: cell division protein FtsQ/DivIB

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: JSNZ_001153
• symbol: JSNZ_001153
• product: cell division protein FtsQ/DivIB
• replicon: chromosome
• strand: +
• coordinates: 1152797..1154116
• length: 1320
• essential: unknown other strains

⊟Accession numbers

• Gene ID:
• RefSeq:
• BioCyc:
• MicrobesOnline:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  1261
  
  ATGGATGATAAAACGAAGAACGATCAACAAGAATCAAATGAAGATAAAGATGAATTAGAA
  TTATTTACGAGGAATACATCTAAGAAAAGACGGCAAAGAAAAAGATCAAAGGCTACACAT
  TTTTCTAATCAAAATAAAGATGATACATCTCAACAAGCTGATTTTGATGAAGAAATTTAC
  TTGATAAATAAAGACTTCAAAAAAGAACAAGGCAATGATGAAAATAATGATTCTGCTTCT
  AGTCGTGCGAATAATAATAATATCGATGATTCTACAGACCCTAATATTGAAAATGAGGAT
  TATAGATATAATCAAGAAATTGACGACAAAAATGAATCGAATGGAATTGCAGTCGACAAC
  GAACAACCTCAATCAGCTCCTAAAGAACAAAATAGCGACTCGAATGATGAGGAAACAGTA
  ACGAAAAAAGAACGAAAAAGTAAAGTAACACAATTAAAGCCATTAACACTTGAAGAAAAG
  CGGAAGTTAAGACGTAAGCGACAAAAACGAATCCAATACAGTGTTATTACAATATTAGTA
  TTGTTGATTGCTGTTATATTAATTTACATGTTTTCACCACTTAGTAAAATTGCGCATGTA
  AATATAAATGGAAATAATCACGTTAGTACTTCAAAGATAAACAAAGTTTTAGGTGTTAAA
  AATGATTCAAGGATGTATACGTTTAGTAAAAAAAATGCTATTAATGATCTTGAAGAGGAT
  CCATTAATCAAAAGTGTTGAGATACACAAGCAATTACCAAACACATTAAACGTAGATATC
  ACAGAAAATGAAATTATTGCTTTAGTGAAATATAAAGGTAAATATTTACCTTTATTAGAA
  AATGGTAAATTGCTTAAAGGTTCAAATGATGTCAAAATTAATGATGCACCTGTCATGGAT
  GGTTTCAAAGGTACAAAAGAAGATGATATGATTAAGGCGTTATCTGAAATGACACCTGAA
  GTTAGACGATATATTGCCGAAGTGACATACGCCCCAAGTAAAAACAAACAAAGCAGAATT
  GAATTGTTTACGACAGATGGACTTCAAGTAATCGGTGATATTTCGACGATATCTAAGAAA
  ATGAAATATTATCCGCAGATGTCACAATCATTATCAAGGGATAGTTCGGGTAAACTAAAA
  ACACGAGGCTATATTGATTTATCAGTCGGTGCTTCATTTATCCCATACCGTGGAAACACG
  TCTAGTCAATCAGAAAGCGATAAAAATGTGACTAAATCATCTCAAGAGGAAAATCAAGCA
  AAAGAAGAATTACAAAGCGTTTTAAACAAAATTAACAAACAATCAAGTAAGAATAATTAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  1020
  1080
  1140
  1200
  1260
  1320
  

⊟Protein

⊟General

• locus tag: JSNZ_001153
• symbol: JSNZ_001153
• description: cell division protein FtsQ/DivIB
• length: 439
• theoretical pI: 8.86455
• theoretical MW: 50153.5
• GRAVY: -1.06469

⊟Function

• TIGRFAM:
  Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides LPS export ABC transporter permease LptF (TIGR04407; HMM-score: 11.6)
  Metabolism Transport and binding proteins Other LPS export ABC transporter permease LptF (TIGR04407; HMM-score: 11.6)
  and 2 more
  Cellular processes Cellular processes Cell division cell division protein ZipA (TIGR02205; HMM-score: 5.6)
  Metabolism Transport and binding proteins Cations and iron carrying compounds K+-dependent Na+/Ca+ exchanger (TIGR00927; HMM-score: 4.4)
• TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
• PFAM:
  POTRA (CL0191) POTRA_1; POTRA domain, FtsQ-type (PF08478; HMM-score: 68.8)
  and 6 more
  no clan defined FtsQ_DivIB_C; Cell division protein FtsQ/DivIB, C-terminal (PF03799; HMM-score: 49.4)
  POTRA (CL0191) POTRA; Surface antigen variable number repeat (PF07244; HMM-score: 16.4)
  BPD_transp_1 (CL0404) LptF_LptG; Lipopolysaccharide export system permease LptF/LptG (PF03739; HMM-score: 12.6)
  no clan defined T2SSF; Type II secretion system (T2SS), protein F (PF00482; HMM-score: 12.5)
  VSA (CL0656) RIFIN; Rifin (PF02009; HMM-score: 11.9)
  no clan defined DUF6480; Family of unknown function (DUF6480) (PF20088; HMM-score: 11.4)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cellwall
  • Cytoplasmic Score: 0.01
  • Cytoplasmic Membrane Score: 0.53
  • Cellwall Score: 8.75
  • Extracellular Score: 0.7
  • Internal Helix: 1
• DeepLocPro: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 0.994
  • Cell wall & surface Score: 0.0001
  • Extracellular Score: 0.0058
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.012397
  • TAT(Tat/SPI): 0.007825
  • LIPO(Sec/SPII): 0.005049
• predicted transmembrane helices (TMHMM): 1

⊟Accession numbers

• GI:
• RefSeq:
• UniProt:

⊟Protein sequence

• MDDKTKNDQQESNEDKDELELFTRNTSKKRRQRKRSKATHFSNQNKDDTSQQADFDEEIYLINKDFKKEQGNDENNDSASSRANNNNIDDSTDPNIENEDYRYNQEIDDKNESNGIAVDNEQPQSAPKEQNSDSNDEETVTKKERKSKVTQLKPLTLEEKRKLRRKRQKRIQYSVITILVLLIAVILIYMFSPLSKIAHVNINGNNHVSTSKINKVLGVKNDSRMYTFSKKNAINDLEEDPLIKSVEIHKQLPNTLNVDITENEIIALVKYKGKYLPLLENGKLLKGSNDVKINDAPVMDGFKGTKEDDMIKALSEMTPEVRRYIAEVTYAPSKNKQSRIELFTTDGLQVIGDISTISKKMKYYPQMSQSLSRDSSGKLKTRGYIDLSVGASFIPYRGNTSSQSESDKNVTKSSQEENQAKEELQSVLNKINKQSSKNN

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications