PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

FunGene: 08-OCT-2024

⊟Summary

• organism: Staphylococcus aureus JSNZ
• locus tag: JSNZ_000753
• pan locus tag^?: SAUPAN002713000
• symbol: JSNZ_000753
• pan gene symbol^?: est
• synonym:
• product: alpha/beta hydrolase

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: JSNZ_000753
• symbol: JSNZ_000753
• product: alpha/beta hydrolase
• replicon: chromosome
• strand: +
• coordinates: 791912..792652
• length: 741
• essential: unknown other strains

⊟Accession numbers

• Gene ID:
• RefSeq:
• BioCyc:
• MicrobesOnline:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  
  ATGCAGATAAAATTACCAAAACCTTTCTTTTTTGAGGAAGGTAAACGTGCCGTGTTATTA
  CTACATGGTTTTACAGGCAATTCGTCTGATGTTCGTCAATTAGGTCGATTTTTACAAAAG
  AAAGGTTATACATCATATGCACCGCAATATGAAGGCCACGCGGCACCACCAGAGGAAATA
  CTGAAATCTAGTCCTTTCGTTTGGTTTAAAGATGCGTTAGATGGTTATGATTATCTTGTT
  GAACAAGGTTATGATGAAATTGTTGTTGCTGGTCTATCATTAGGTGGGGATTTTGCTTTA
  AAATTAAGCTTAAATAGAGATGTAAAGGGTATTGTAACGATGTGTGCTCCTATGGGTGGC
  AAAACTGAAGGTGCCATTTATGAAGGCTTTTTAGAATATGCACGCAATTTTAAAAAGTAT
  GAGGGTAAAGATCAAGAAACGATTGACAACGAAATGCATCATTTTAAACCAACTGAAACT
  TTAAAAGAATTAAGTGAAGCATTAGATACGATTAAAGATCAAGTTGATGAGGTGTTTGAC
  CCAATTTTAGTGATTCAAGCAGAAAACGACAATATGATTGATCCACAATCCGCAAATTAT
  ATATATGAACATGTAGACTCTGACGATAAAAATATCAAGTGGTACAGTGAATCTGGACAT
  GTTATTACGATTGATAAAGAAAAAGAACAAGTATTTGAAGATATTTATCAATTTTTAGAG
  TCATTAGATTGGTCAGAATAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  741
  

⊟Protein

⊟General

• locus tag: JSNZ_000753
• symbol: JSNZ_000753
• description: alpha/beta hydrolase
• length: 246
• theoretical pI: 4.33302
• theoretical MW: 28164.3
• GRAVY: -0.515447

⊟Function

• TIGRFAM:
  Plasmodium subtelomeric family (TIGR01607; HMM-score: 28.7)
  Metabolism Fatty acid and phospholipid metabolism Biosynthesis poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit (TIGR01836; HMM-score: 24.3)
  and 3 more
  Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (TIGR03695; EC 4.2.99.20; HMM-score: 22.5)
  Metabolism Energy metabolism Other 3-oxoadipate enol-lactonase (TIGR02427; EC 3.1.1.24; HMM-score: 20.1)
  Metabolism Energy metabolism Photosynthesis putative magnesium chelatase accessory protein (TIGR03056; HMM-score: 10.9)
• TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
• PFAM:
  AB_hydrolase (CL0028) Hydrolase_4; Serine aminopeptidase, S33 (PF12146; HMM-score: 75.1)
  and 13 more
  Abhydrolase_1; alpha/beta hydrolase fold (PF00561; HMM-score: 40.3)
  DLH; Dienelactone hydrolase family (PF01738; HMM-score: 34.5)
  Abhydrolase_6; Alpha/beta hydrolase family (PF12697; HMM-score: 29.7)
  Peptidase_S9; Prolyl oligopeptidase family (PF00326; HMM-score: 26.5)
  ABHD18; Alpha/beta hydrolase domain containing 18 (PF09752; HMM-score: 19.2)
  Abhydrolase_3; alpha/beta hydrolase fold (PF07859; HMM-score: 16.2)
  FSH1; Serine hydrolase (FSH1) (PF03959; HMM-score: 15.6)
  UPF0227; Uncharacterised protein family (UPF0227) (PF05728; HMM-score: 15.6)
  Abhydrolase_11; Alpha/beta hydrolase domain (PF20408; HMM-score: 15.3)
  Chlorophyllase; Chlorophyllase (PF07224; HMM-score: 15.1)
  LisH (CL0561) LisH; LisH (PF08513; HMM-score: 13.9)
  no clan defined DUF4611; Domain of unknown function (DUF4611) (PF15387; HMM-score: 13.2)
  AB_hydrolase (CL0028) PGAP1; PGAP1-like alpha/beta domain (PF07819; HMM-score: 12.2)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.8856
  • Cytoplasmic Membrane Score: 0.0896
  • Cell wall & surface Score: 0.0014
  • Extracellular Score: 0.0234
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.014187
  • TAT(Tat/SPI): 0.008702
  • LIPO(Sec/SPII): 0.004092
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq:
• UniProt:

⊟Protein sequence

• MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPQYEGHAAPPEEILKSSPFVWFKDALDGYDYLVEQGYDEIVVAGLSLGGDFALKLSLNRDVKGIVTMCAPMGGKTEGAIYEGFLEYARNFKKYEGKDQETIDNEMHHFKPTETLKELSEALDTIKDQVDEVFDPILVIQAENDNMIDPQSANYIYEHVDSDDKNIKWYSESGHVITIDKEKEQVFEDIYQFLESLDWSE

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell: data available for COL
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: data available for COL

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications