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NCBI: 01-DEC-2025

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: EGJ38_001597 [new locus tag: EGJ38_RS07975 ]
  • pan locus tag?: SAUPAN004204000
  • symbol: EGJ38_001597
  • pan gene symbol?: —
  • synonym:
  • alternate name: JSNZ_001597
  • product: biotin-dependent carboxyltransferase family protein

⊟Additional information (user-provided)[edit | edit source]

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EGJ38_001597 [new locus tag: EGJ38_RS07975 ]
  • symbol: EGJ38_001597
  • product: biotin-dependent carboxyltransferase family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1632030..1633040
  • length: 1011
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq: MGT2423554 NCBI
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGTCAATTAAGATTTTACAACCAGGTCTCTTTTCAACGGTACAAGATCTAGGAAGAAAA
    GGTTATGAACATATTGGATTTTCAGGCGCAGGTGCCATGGATCAATTTAGTTTTAAGGTT
    GCGCAGTCATTAATTAACAATGATGGTCCAGCGATTGAATATACTTTGATTGGTCCTACC
    ATTCAATTTAATACGCAAAATACATTTGTTATAACCGGTGGTAGTGTTAATGCTTCGCTA
    AATAATAGAACTATATCAATGAATTCTGTCATATTAGTTGAGAAAGGTGACATTTTAAAA
    ATAGGTGCTATAACCAAAGGTGCACGCGGTTATCTTACTTTTGGTCATTCTATCAACGTA
    CCTCCTATTGCTGAAAGTTATGCAACACATACCCGAAGCAGTATAGGAGGATTCAAAGGT
    AGAAAGTTATTAGCTAATGATGTAATAACAGTGAAAATAAATAATGACTTTAAAGAAAAC
    ATTGGAAAGACTATTCATTTACAGGACGATTTATTGCCAGAAAATAATATTATACACATT
    CTTCAAGGACCTCAATTCGAGGCATTTTCTGAAGAGGCTAGAGCGAAAATTGTAAATCAT
    CCATATTTAATTACTGAACAATCAGACCGTATGGGCTATCGTTTGGAAGGTGACAGCGTT
    GCACCAATTAATCAAGCAGATATCATTTCTGAACCGGTTGCTCTTGGTAGTGTTCAAGTA
    CCAAATGATGGTCAACCTATTATTCTGCTTAATGATAAACAAACGATAGGTGGTTATACC
    AAAATTGCAACTGTATGCAAATTTGATCTGCCAAAGTTAGCACAGATGAAACCACAAGAT
    ACAATTCAATTTAAATGGATATCATTCCAAGAAGCTGTAGATAAGAATCGGGAACAAATG
    TCTCTGTTTAATGAAATTCTTAAGAGTCATCAAAAGACTCCAATTTTTGATACATCTAGC
    TTGCGACATACTTCGAAAAAATTAGCAACAATTTTAAAAGGGGATTTGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1011


⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EGJ38_001597 [new locus tag: EGJ38_RS07975 ]
  • symbol: EGJ38_001597
  • description: biotin-dependent carboxyltransferase family protein
  • length: 336
  • theoretical pI: 8.42031
  • theoretical MW: 36968
  • GRAVY: -0.201786

⊟Function[edit | edit source]

  • TIGRFAM:
    Unknown function General biotin-dependent carboxylase uncharacterized domain (TIGR00724; HMM-score: 270.2)
    and 1 more
    Metabolism Central intermediary metabolism Nitrogen metabolism urea carboxylase (TIGR02712; EC 6.3.4.6; HMM-score: 171.5)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    Cyclophil-like (CL0475) CT_A_B; Carboxyltransferase domain, subdomain A and B (PF02626; HMM-score: 273.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.759
    • Cytoplasmic Membrane Score: 0.2284
    • Cell wall & surface Score: 0.0008
    • Extracellular Score: 0.0117
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.017826
    • TAT(Tat/SPI): 0.001465
    • LIPO(Sec/SPII): 0.0016
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: MGT2423554 NCBI
  • UniProt:

⊟Additional information (user-provided)[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSIKILQPGLFSTVQDLGRKGYEHIGFSGAGAMDQFSFKVAQSLINNDGPAIEYTLIGPTIQFNTQNTFVITGGSVNASLNNRTISMNSVILVEKGDILKIGAITKGARGYLTFGHSINVPPIAESYATHTRSSIGGFKGRKLLANDVITVKINNDFKENIGKTIHLQDDLLPENNIIHILQGPQFEAFSEEARAKIVNHPYLITEQSDRMGYRLEGDSVAPINQADIISEPVALGSVQVPNDGQPIILLNDKQTIGGYTKIATVCKFDLPKLAQMKPQDTIQFKWISFQEAVDKNREQMSLFNEILKSHQKTPIFDTSSLRHTSKKLATILKGDL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CcpA regulon
    CcpA(TF)important in Carbon catabolism;  regulation predicted or transferred from N315 and NCTC 8325  [2]

⊟Additional information (user-provided)[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Other information (user-provided)[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)
  2. ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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