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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS07990 [old locus tag: SA1415 ]
  • pan locus tag?: SAUPAN004173000
  • symbol: SA_RS07990
  • pan gene symbol?: holA
  • synonym:
  • product: DNA polymerase III subunit delta

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS07990 [old locus tag: SA1415 ]
  • symbol: SA_RS07990
  • product: DNA polymerase III subunit delta
  • replicon: chromosome
  • strand: -
  • coordinates: 1621306..1622280
  • length: 975
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (1621306..1622280) NCBI
  • BioCyc: SA_RS07990 BioCyc
  • MicrobesOnline: see SA1415

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAGCGACAATATTGTAGCTATTTATGGAGATGTGCCTGAATTGGTTGAAAAACAAAGT
    GCAGAAATCATATCACAATTTTTGAAAAGTGATAGAGATGACTTTAACTTTGTGAAATAT
    AATTTATACGAAAAAGAGATTGCACCAATTGTTGAAGAAACATTAACATTGCCTTTCTTT
    TCAGATAAAAAAGCAATTTTGGTTAAAAATGCATATATATTTACAGGTGAAAAAGCGCCA
    AAAGATATGGCTCATAATGTAGATCAATTAATAGAATTTATTGAAAAATATGATGGCGAA
    AATTTGATTGTCTTTGAGATATATCAAAATAAACTTGATGAAAGAAAAAAGTTAACTAAA
    ACTCTAAAAAAGCATGCAAGGCTTAAAAAAATAGAGCAAATGTCTGAAGAAGAAATAAAA
    AAATGGATTCAAAGTAAATTAAATGAGAATTTCAAAGATATCAAAAGAGATGCATTAGAT
    TTATTTATTGAGTTGACAGGTATTAACTTTAATATTGTCTCACAAGAGATAGAAAAGTTG
    ATTTTATTTTTAGGCGATAGACCAACAATTAATAAGCAGGATGTTAACCAAATTATTAAT
    AGAAGTTTAGAGCAAAATGTATTTTTACTGACTGAATACATTCAGAAAAGAAAGAAAGAA
    CAAGCAATTCATTTAGTAAAAGATTTAATAACTATGAAAGAAGAACCAATTAAATTACTT
    GCACTAATTACAAGTAATTACCGATTATTTTATCAATGTAAGATTCTGAGTCAAAAAGGA
    TATAGTGGACAGCAAATTGCTAAAACAATAGGAGTGCATCCATACAGAGTAAAATTAGCG
    TTAGGACAAGTAAGACATTATCAACTTGATGAATTATTGAATATTGTAGATGCTTGTGCG
    GAAACTGATTATAAACTTAAATCATCATATATGGATAAACAGTTAATACTGGAATTATTC
    ATTCTATCTTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    975

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS07990 [old locus tag: SA1415 ]
  • symbol: SA_RS07990
  • description: DNA polymerase III subunit delta
  • length: 324
  • theoretical pI: 7.06335
  • theoretical MW: 37948.8
  • GRAVY: -0.311111

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA polymerase III, delta subunit (TIGR01128; EC 2.7.7.7; HMM-score: 296.2)
    and 1 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA polymerase III, subunit gamma and tau (TIGR02397; EC 2.7.7.7; HMM-score: 14.9)
  • TheSEED: see SA1415
  • ⊞PFAM:
    post-AAA (CL0604) DNA_pol3_delta_C; DNA polymerase III delta subunit, C-terminal domain (PF21694; HMM-score: 149.8)
    P-loop_NTPase (CL0023) DNA_pol3_delta; DNA polymerase III, delta subunit (PF06144; HMM-score: 120.5)
    and 9 more
    MmeI_HD-like (CL0884) YtxK_like; YtxK N-terminal helical domain (PF21106; HMM-score: 17.8)
    no clan defined DUF2018; Domain of unknown function (DUF2018) (PF09442; HMM-score: 15.5)
    DisA-linker; DisA bacterial checkpoint controller linker region (PF10635; HMM-score: 13.3)
    KNTase_C (CL0291) YgxA-like_sub_bind; YgxA-like substrate binding domain (PF22339; HMM-score: 13.3)
    no clan defined DUF3781; Protein of unknown function (DUF3781) (PF12636; HMM-score: 12.5)
    DUF7529; Family of unknown function (DUF7529) (PF24373; HMM-score: 12.4)
    P-loop_NTPase (CL0023) Sigma54_activ_2; Sigma-54 interaction domain (PF14532; HMM-score: 11.9)
    Helicase_C; Helicase conserved C-terminal domain (PF00271; HMM-score: 11.1)
    no clan defined DUF3819; CCR4-Not complex, Not1 subunit, domain of unknown function DUF3819 (PF12842; HMM-score: 11.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9693
    • Cytoplasmic Membrane Score: 0.0235
    • Cell wall & surface Score: 0.0038
    • Extracellular Score: 0.0034
  • LocateP:
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001644
    • TAT(Tat/SPI): 0.000165
    • LIPO(Sec/SPII): 0.0003
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYEKEIAPIVEETLTLPFFSDKKAILVKNAYIFTGEKAPKDMAHNVDQLIEFIEKYDGENLIVFEIYQNKLDERKKLTKTLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALDLFIELTGINFNIVSQEIEKLILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRKKEQAIHLVKDLITMKEEPIKLLALITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYRVKLALGQVRHYQLDELLNIVDACAETDYKLKSSYMDKQLILELFILSL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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