PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

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⊟Summary

• organism: Staphylococcus aureus COL
locus tag: SACOL_RS02470 [old locus tag: SACOL0488 ]
pan locus tag^?: SAUPAN002149000
symbol: SACOL_RS02470
pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SACOL_RS02470 [old locus tag: SACOL0488 ]
• symbol: SACOL_RS02470
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 489723..490046
• length: 324
• essential: unknown other strains

⊟Accession numbers

• Location: NC_002951 (489723..490046) NCBI
• BioCyc: SACOL_RS02470 BioCyc
• MicrobesOnline: see SACOL0488

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  
  ATGATGTTTAATCAAATTAATAATAAAAATGAATTAGAAGAATCATATGAATCTGAGAAA
  AAACGTATAGAGAATGAACTGCAAAATTTAAATGAACTTAGGCATAGAACTCGAAAAGAA
  AATGAACGTAGTTATGATGTTTTTCAATATTTGAAGCACGAAATGAATTATAGTGAAGAT
  GCCCAAAGGAAAATGACGAGAAATATAGAAGCGTATGAGCAAGAAATCAATGAGATAATT
  AGAAAGCAAGAATGGAAATTAGAAGAATATAAAGAAGACTTAAAAAAGTCTTATGAAAAG
  CAGTTAGATAAGCTAAGTGACTGA
  60
  120
  180
  240
  300
  324
  

⊟Protein

⊟General

• locus tag: SACOL_RS02470 [old locus tag: SACOL0488 ]
• symbol: SACOL_RS02470
• description: hypothetical protein
• length: 107
• theoretical pI: 4.94933
• theoretical MW: 13457.8
• GRAVY: -1.69252

⊟Function

• ⊞TIGRFAM:
  Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02169; HMM-score: 9)
  Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02169; HMM-score: 9)
  Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02168; HMM-score: 7.9)
  Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02168; HMM-score: 7.9)
  and 4 more
  Genetic information processing DNA metabolism Other MutS2 family protein (TIGR01069; HMM-score: 5.6)
  two transmembrane protein (TIGR04527; HMM-score: 5.6)
  Genetic information processing Transcription Degradation of RNA ribonuclease Y (TIGR03319; EC 3.1.-.-; HMM-score: 3.6)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion membrane fusion protein, HlyD family (TIGR01843; HMM-score: 3.1)
• TheSEED: see SACOL0488
• ⊞PFAM:
  no clan defined Cluap1; Clusterin-associated protein-1 (PF10234; HMM-score: 16.5)
  ISG65-75; Invariant surface glycoprotein (PF11727; HMM-score: 15.6)
  dUTPase (CL0153) Herpes_U55; Human herpesvirus U55 protein (PF06501; HMM-score: 14.1)
  and 15 more
  6PGD_C (CL0106) Octopine_DH; NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain (PF02317; HMM-score: 12.2)
  no clan defined KxDL; Uncharacterized conserved protein (PF10241; HMM-score: 12.1)
  OVT1; Major antigen, helical domain (PF24423; HMM-score: 12)
  YlqD; YlqD protein (PF11068; HMM-score: 11.3)
  PEP-utilisers_N; PEP-utilising enzyme, N-terminal (PF05524; HMM-score: 10.9)
  LTXXQ-like (CL0515) DUF4890; Domain of unknown function (DUF4890) (PF16231; HMM-score: 10.3)
  no clan defined Exonuc_VII_L; Exonuclease VII, large subunit (PF02601; HMM-score: 10.1)
  VBS-like (CL0705) HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1 (PF16515; HMM-score: 10)
  ATP_synthase (CL0255) V-ATPase_G_2; Vacuolar (H+)-ATPase G subunit (PF16999; HMM-score: 8.3)
  no clan defined Fib_alpha; Fibrinogen alpha/beta chain family (PF08702; HMM-score: 8.1)
  CREPT; Cell-cycle alteration and expression-elevated protein in tumour (PF16566; HMM-score: 8)
  UPF0242; Uncharacterised protein family (UPF0242) N-terminus (PF06785; HMM-score: 7.3)
  P-loop_NTPase (CL0023) SRPRB; Signal recognition particle receptor beta subunit (PF09439; HMM-score: 6.5)
  GT-B (CL0113) FUT8_N_cat; Alpha-(1,6)-fucosyltransferase N- and catalytic domains (PF19745; HMM-score: 6.5)
  no clan defined V_ATPase_I; V-type ATPase 116kDa subunit family (PF01496; HMM-score: 4.6)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• ⊞PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• ⊞DeepLocPro: Extracellular
  • Cytoplasmic Score: 0.349
  • Cytoplasmic Membrane Score: 0.0534
  • Cell wall & surface Score: 0.022
  • Extracellular Score: 0.5756
• LocateP:
• ⊞SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.005221
  • TAT(Tat/SPI): 0.000691
  • LIPO(Sec/SPII): 0.001015
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446894242 NCBI
• RefSeq: WP_000971498 NCBI
• UniProt: see SACOL0488

⊟Protein sequence

• MMFNQINNKNELEESYESEKKRIENELQNLNELRHRTRKENERSYDVFQYLKHEMNYSEDAQRKMTRNIEAYEQEINEIIRKQEWKLEEYKEDLKKSYEKQLDKLSD

⊟Experimental data

• experimentally validated: see SACOL0488
• protein localization: see SACOL0488
• quantitative data / protein copy number per cell: see SACOL0488
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊞Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊞Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications