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NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1469 [new locus tag: SA_RS08275 ]
  • pan locus tag?: SAUPAN004249000
  • symbol: SA1469
  • pan gene symbol?: thrR
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA1469 [new locus tag: SA_RS08275 ]
  • symbol: SA1469
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1677944..1678402
  • length: 459
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGATGGACAATAAAGATTATAAAAAGTTTTATTTAATTAGAGAAGATGTCTTGCCTGAA
    TCCGTGGTTAAAACATTGAAGATTAAAGATGCCTTAAAAAGTGATCCGACATTGTCCATT
    TATGATGCCGTTAAACAGTTTGATCTATCTAGAAGTGCTTTTTATAAATATAGAGAAACG
    ATATTTCCAGTAGACGATAAAATGCTTGACCATCGAGAATTTACATTAATTTTATATGTA
    ACTGATATTGTGGGTATGTTGGCACGTGTACTAGATGTTATATCAAAGTTAGAACTATCT
    GTATTAACGATTCATCAAAGTATTCCAATGGAAGAAAAAGCAACAATAACATTATCACTG
    AATGCTAAATCTAAAGAAACTTCAGTAGAAGATGTTATTGGTGCTTTGAGAAATTTAGAT
    TATGTATCAAAAGTAGAATTAATTAGTATGAGTATGTAA
    60
    120
    180
    240
    300
    360
    420
    459

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA1469 [new locus tag: SA_RS08275 ]
  • symbol: SA1469
  • description: hypothetical protein
  • length: 152
  • theoretical pI: 5.3108
  • theoretical MW: 17474.3
  • GRAVY: -0.0151316

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Amino acid biosynthesis Aspartate family aspartate kinase (TIGR00657; EC 2.7.2.4; HMM-score: 13.1)
  • TheSEED  :
    • ACT domain-containing protein
  • ⊞PFAM:
    ACT (CL0070) ACT_4; ACT domain (PF13291; HMM-score: 24.9)
    ACT; ACT domain (PF01842; HMM-score: 21.5)
    and 5 more
    bHLH-TF_ACT-like_plant; Plant bHLH transcription factor, ACT-like domain (PF22754; HMM-score: 19)
    ACT_5; ACT domain (PF13710; HMM-score: 14.9)
    no clan defined DUF5896; Family of unknown function (DUF5896) (PF19248; HMM-score: 14.2)
    ACT (CL0070) ACT_AHAS_ss; AHAS small subunit-like ACT domain (PF22629; HMM-score: 13.3)
    HTH (CL0123) HTH_7; Helix-turn-helix domain of resolvase (PF02796; HMM-score: 12)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.7601
    • Cytoplasmic Membrane Score: 0.0444
    • Cell wall & surface Score: 0.0005
    • Extracellular Score: 0.195
  • ⊞LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002306
    • TAT(Tat/SPI): 0.000148
    • LIPO(Sec/SPII): 0.000539
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MMDNKDYKKFYLIREDVLPESVVKTLKIKDALKSDPTLSIYDAVKQFDLSRSAFYKYRETIFPVDDKMLDHREFTLILYVTDIVGMLARVLDVISKLELSVLTIHQSIPMEEKATITLSLNAKSKETSVEDVIGALRNLDYVSKVELISMSM

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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