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NCBI: 03-AUG-2016
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus NCTC8325
- locus tag: SAOUHSC_01876
- pan locus tag?: SAUPAN004444000
- symbol: SAOUHSC_01876
- pan gene symbol?: —
- synonym:
- product: hypothetical protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SAOUHSC_01876
- symbol: SAOUHSC_01876
- product: hypothetical protein
- replicon: chromosome
- strand: -
- coordinates: 1791523..1792704
- length: 1182
- essential: no DEG other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3921765 NCBI
- RefSeq: YP_500379 NCBI
- BioCyc: G1I0R-1745 BioCyc
- MicrobesOnline: 1290293 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1141ATGAATATACCTAAATCAGTCTGGTGGCTAGTAATTGGCATGGCGTTAAATATTACTGGT
TCCAGTTTTTTGTGGCCTTTAAATACAATTTATATGAAACAAGAACTTGGAAAAAGTTTA
ACTGTTGCTGGTTTAGTGCTAATGATAAATTCATTTGGCATGGTTATTGGAAACTTATTA
GGTGGTTCACTATTTGATAAATTAGGTGGATACAAGACGATTTTAATTGGAACTTTCACT
TGTCTTTGTAGTACAACGCTACTTAATTTCTTTCACGGGTGGCCTTGGTATGCTGTATGG
CTTGTAATGTTAGGGTTTGGTGGCGGAATGATTATTCCTGCGATATACGCTATGGCTGGA
GCAGTGTGGCCAAATGGCGGAAGACAAACGTTTAATGCGATATACTTAGCGCAAAATATT
GGTGTGGCTGTCGGTGCTGCAATGGGCGGCTTTGTCGCAGAATTTAGCTTTAACTATATC
TTTTTAGCCAATCTTATTATGTATGTTGTGTTTGCGCTTGTCGCGGTAACGCAATTTAAT
ATTGAAATTAATGCGAAAGTTAAATATCCAACTCATTTAGATATTACTGGTAAAAAGAAT
AAAGCAAGATTTATTTCATTAGTACTAATTTGTGCAATGTTTGCAATTTGTTGGGTTGCA
TATATTCAATGGGAGTCTACAATCGCTTCATTTACACAATCTATTAATATTTCAATGGCA
CAATATAGTGTTTTATGGACAATTAACGGAATAATGATTTTAGTAGCACAACCATTAATT
AAACCGATTCTCTATCTGTTAAAAGGAAACTTAAAGAAGCAAATGTTTGTCGGCATCATC
ATTTTTATGTTGTCGTTCTTTGTCACGAGTTTTGCCGAAAACTTTACAATATTTGTTGTC
GGTATGATTATTTTAACTTTTGGAGAAATGTTTGTATGGCCAGCAGTTCCAACTATAGCC
AATCAGTTAGCGCCAGATGGTAAGCAAGGACAGTACCAAGGTTTTGTGAATTCAGCTGCT
ACAGTAGGAAAAGCATTTGGTCCATTTCTTGGTGGTGTATTAGTTGATGCGTTTAATATG
CGCATGATGTTTATCGGTATGATGCTACTACTTGTATTTGCATTAATATTATTAATGGTT
TTCAAGGAGAATAATACGCAACCTAAAAAAATAGATGCATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SAOUHSC_01876
- symbol: SAOUHSC_01876
- description: hypothetical protein
- length: 393
- theoretical pI: 9.75148
- theoretical MW: 43344.8
- GRAVY: 0.840204
⊟Function[edit | edit source]
- ⊞TIGRFAM: multidrug resistance protein (TIGR00880; HMM-score: 72.2)Transport and binding proteins Carbohydrates, organic alcohols, and acids D-galactonate transporter (TIGR00893; HMM-score: 69.8)and 8 more
- TheSEED :
- Multidrug resistance protein
- ⊞PFAM: MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 161)and 1 more
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAGLVLMINSFGMVIGNLLGGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLVMLGFGGGMIIPAIYAMAGAVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYIFLANLIMYVVFALVAVTQFNIEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICWVAYIQWESTIASFTQSINISMAQYSVLWTINGIMILVAQPLIKPILYLLKGNLKKQMFVGIIIFMLSFFVTSFAENFTIFVVGMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQGFVNSAATVGKAFGPFLGGVLVDAFNMRMMFIGMMLLLVFALILLMVFKENNTQPKKIDA
⊟Experimental data[edit | edit source]
- experimentally validated: PeptideAtlas [1] [2]
- protein localization: data available for COL
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- predicted SigA promoter [3] : leuS < S740 < SAOUHSC_01876
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: [3]
⊟Multi-gene expression profiles
Click on any data point to display a description of the corresponding condition!
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊞Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊞Other Information[edit | edit source]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Maren Depke, Stephan Michalik, Alexander Rabe, Kristin Surmann, Lars Brinkmann, Nico Jehmlich, Jörg Bernhardt, Michael Hecker, Bernd Wollscheid, Zhi Sun, Robert L Moritz, Uwe Völker, Frank Schmidt
A peptide resource for the analysis of Staphylococcus aureus in host-pathogen interaction studies.
Proteomics: 2015, 15(21);3648-61
[PubMed:26224020] [WorldCat.org] [DOI] (I p) - ↑ Stephan Michalik, Maren Depke, Annette Murr, Manuela Gesell Salazar, Ulrike Kusebauch, Zhi Sun, Tanja C Meyer, Kristin Surmann, Henrike Pförtner, Petra Hildebrandt, Stefan Weiss, Laura Marcela Palma Medina, Melanie Gutjahr, Elke Hammer, Dörte Becher, Thomas Pribyl, Sven Hammerschmidt, Eric W Deutsch, Samuel L Bader, Michael Hecker, Robert L Moritz, Ulrike Mäder, Uwe Völker, Frank Schmidt
A global Staphylococcus aureus proteome resource applied to the in vivo characterization of host-pathogen interactions.
Sci Rep: 2017, 7(1);9718
[PubMed:28887440] [WorldCat.org] [DOI] (I e) - ↑ Jump up to: 3.0 3.1 Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
PLoS Genet: 2016, 12(4);e1005962
[PubMed:27035918] [WorldCat.org] [DOI] (I e)