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⊟Summary[edit | edit source]
- pan ID?: SAUPAN004444000
- symbol?: —
- synonym:
- description?: MFS transporter
- MFS transporter
- drug transporter
- MDR family MFS transporter
- multidrug resistance protein, putative
- multidrug resistance transporter protein B
- putative drug transporter
- multidrug resistance protein
- drug transporter, putative
- major facilitator superfamily protein
- major facilitator transporter
- MFS family major facilitator transporter
- multidrug resistance protein B
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 4692657..4693800
- synteny block?: BlockID0034420
- occurrence?: in 97% of 34 strains
tetracycline efflux MFS family transporter [1]
• this gene / gene-product does not have a proposed name, just a documented function as a tetracycline/doxycycline efflux system in USA300_FPR3757
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1717
08BA02176:
C248_1806
11819-97:
MS7_1765
6850:
RSAU_001616
71193:
ST398NM01_1812
ECT-R 2:
ECTR2_1599
ED133:
SAOV_1745
ED98:
SAAV_1770
HO 5096 0412:
SAEMRSA15_16670
JH1:
SaurJH1_1849
JH9:
SaurJH9_1814
JKD6008:
SAA6008_01731
JKD6159:
SAA6159_01682
LGA251:
SARLGA251_16490
M013:
M013TW_1775
MRSA252:
SAR1844
MSHR1132:
SAMSHR1132_16090
MSSA476:
SAS1685
Mu3:
SAHV_1747
Mu50:
SAV1761
MW2:
MW1702
RF122:
SAB1619c
ST398:
SAPIG1812
T0131:
—
TCH60:
HMPREF0772_11392
TW20:
SATW20_17490
USA300_TCH1516:
USA300HOU_1750
VC40:
SAVC_08005
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 | |
| JSNZ |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAGLVLMINSFGMVIGNLL
N315 MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAGLVLMINSFGMVIGNLL
NCTC8325 MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAGLVLMINSFGMVIGNLL
Newman MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAGLVLMINSFGMVIGNLL
USA300_FPR3757 MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAGLVLMINSFGMVIGNLL
************************************************************
COL GGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLVMLGFGGGMIIPAIYAMAG
N315 GGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLVMLGFGGGMIIPAIYAMAG
NCTC8325 GGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLVMLGFGGGMIIPAIYAMAG
Newman GGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLVMLGFGGGMIIPAIYAMAG
USA300_FPR3757 GGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLVMLGFGGGMIIPAIYAMAG
************************************************************
COL AVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYIFLANLIMYVVFALVAVTQFN
N315 AVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYIFLANLIMYVVFALVAVTQFN
NCTC8325 AVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYIFLANLIMYVVFALVAVTQFN
Newman AVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYIFLANLIMYVVFALVAVTQFN
USA300_FPR3757 AVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYIFLANLIMYVVFALVAVTQFN
************************************************************
COL IEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICWVAYIQWESTIASFTQSINISMA
N315 IEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICWVAYIQWESTIASFTQSINISMA
NCTC8325 IEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICWVAYIQWESTIASFTQSINISMA
Newman IEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICWVAYIQWESTIASFTQSINISMA
USA300_FPR3757 IEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICWVAYIQWESTIASFTQSINISMA
************************************************************
COL QYSVLWTINGIMILVAQPLIKPILYLLKGNLKKQMFVGIIIFMLSFFVTSFAENFTIFVV
N315 QYSVLWTINGIMILVAQPLIKPVLYLLKGNLKKQMFVGIIIFMLSFFVTSFAENFTIFVV
NCTC8325 QYSVLWTINGIMILVAQPLIKPILYLLKGNLKKQMFVGIIIFMLSFFVTSFAENFTIFVV
Newman QYSVLWTINGIMILVAQPLIKPILYLLKGNLKKQMFVGIIIFMLSFFVTSFAENFTIFVV
USA300_FPR3757 QYSVLWTINGIMILVAQPLIKPILYLLKGNLKKQMFVGIIIFMLSFFVTSFAENFTIFVV
**********************:*************************************
COL GMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQGFVNSAATVGKAFGPFLGGVLVDAFNM
N315 GMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQGFVNSAATVGKAFGPFLGGVLVDAFNM
NCTC8325 GMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQGFVNSAATVGKAFGPFLGGVLVDAFNM
Newman GMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQGFVNSAATVGKAFGPFLGGVLVDAFNM
USA300_FPR3757 GMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQGFVNSAATVGKAFGPFLGGVLVDAFNM
************************************************************
COL RMMFIGMMLLLVFALILLMVFKENNTQPKKIDA
N315 RMMFIGMMLLLVFALILLMVFKENNTQPKKIDA
NCTC8325 RMMFIGMMLLLVFALILLMVFKENNTQPKKIDA
Newman RMMFIGMMLLLVFALILLMVFKENNTQPKKIDA
USA300_FPR3757 RMMFIGMMLLLVFALILLMVFKENNTQPKKIDA
*********************************
- ↑ Daiyu Li, Yan Ge, Ning Wang, Yun Shi, Gang Guo, Quanming Zou, Qiang Liu
Identification and Characterization of a Novel Major Facilitator Superfamily Efflux Pump, SA09310, Mediating Tetracycline Resistance in Staphylococcus aureus.
Antimicrob Agents Chemother: 2023, 67(4);e0169622
[PubMed:36951566] [WorldCat.org] [DOI] (I p)