⊟Summary[edit | edit source]

PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 26-AUG-2013

⊟Summary

• organism: Staphylococcus aureus N315
locus tag: SA0406 [new locus tag: SA_RS02320 ]
pan locus tag^?: SAUPAN002146000
symbol: SA0406
pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA0406 [new locus tag: SA_RS02320 ]
• symbol: SA0406
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 465491..466816
• length: 1326
• essential: no DEG other strains

⊟Accession numbers

• Gene ID: 1123190 NCBI
• RefSeq: NP_373657 NCBI
• BioCyc: see SA_RS02320
• MicrobesOnline: 102683 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  1261
  1321
  
  ATGAAAGATAAATACAAAATAGATCCAGGGATTATTAAAAATAATACAGAGGAAACTACA
  GCTATTTCTAAAATCAGCTACGAAGTTGAAAATGCGAATTTATATGGAGCTGATAGTGAA
  GATATAACAAGACAAATAGAATATTTGAAAGCCAAAAAAAAATTCCCTTCTAATCTTGAA
  TATGTTGATAGTTACACTGATTCTCTTAATGGAGTAACAACTTCTGCTTTTTTAAATAAA
  GATACAGGCAAAGTAACTCTTGGGATGACTGGGACTAATATACAAGGCGAAGCCTTTAAA
  AAGTTAAAAGAAGGTGAATTTTCAAGACAAAATGTTACCAATGCTTTGGAAACAGTTAAA
  GATGGATATGCAGATCTTAAAATATTATATTCTCCTGCATCTGATCAAAACTATAGATAT
  GCGAATACACAAGAATTTATAAATAAAATAAAAAGTAAGTATGACATTGATTTTATTACT
  GGTCATTCACTAGGTGGAAGAGATGCGGTAGTTCTTGGAATGAGTAATGGTATTCCGAAC
  ATTGTGGTTTATAATCCAGCTCCTATTTCTATAAATAGTTTGAATCCTAATTCCCCAGAT
  GGAAAACGATTGTTAGAGTTATATAAAAATTATAAAGGTAATATTACTAGGTTTGTTGCA
  GAAAATGATGCATTGACAGAAAATCTGAAGAAATATAAGCATTATGTTTTTTTCGGTAAT
  GATAAAGTCTTTAAAAATGGTAAAGGTCATGAAATGGAAGGCTTTCTGACCGAAGAAGAA
  CAAAAAGCTATAAAAAAAGAACTTAAAAAACTACAAGGTTATGCAGAAGAAAATAATAAG
  TCATTTGTAAAGAATTCAAATAATGCTATCTCTAAATTAGCTAGTATAGAATTACTTAGA
  GCAAATATGATGACTACAAATGGAGGAGGATTATCTTCTTCGCAGCAAAAAGTTTTAGAA
  AGTTTAACAGCTTTAACAATTGCGCAGTCATTCAGTCAACTGATAGACGATGAAATTAAT
  CAAATCAAAAAAATGTATAATGAAAAGAAAAAGGAATTTGGAAAAAATTGGGAAGACGCT
  CAAAAAGCTGGAAAAGCTGTAGGTGAAGATTTGAGTGTAAATGGAGTTCTCAATGCTTTA
  GATGAAGGTCAAGTGAATGAAAGTAGTATGGTAAGAGAACCTGAACAAATGATATCTGCA
  AAAGAAAGACAACTTTCAACGATAGGGTCTTCTGTATCAAATTATATTATGAGAGTTAGA
  CTCAGTATTAATGAAATCGTTGATAAAGATCAAGTGCTTGCATCACAAATAGGTGGATTA
  CTATGA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  1020
  1080
  1140
  1200
  1260
  1320
  1326
  

⊟Protein

⊟General

• locus tag: SA0406 [new locus tag: SA_RS02320 ]
• symbol: SA0406
• description: hypothetical protein
• length: 441
• theoretical pI: 6.84039
• theoretical MW: 49149.1
• GRAVY: -0.593878

⊟Function

• TIGRFAM:
• TheSEED  :
  • FIG01107856: hypothetical protein
• ⊞⊞PFAM:
  AB_hydrolase (CL0028) Lipase_3; Lipase (class 3) (PF01764; HMM-score: 14.1)
  BD-FAE; BD-FAE (PF20434; HMM-score: 13.9)
  UPF0227; Uncharacterised protein family (UPF0227) (PF05728; HMM-score: 12.7)
  and 1 more
  RXXXE-like (CL0797) DUF5677; Family of unknown function (DUF5677) (PF18928; HMM-score: 7.2)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• ⊞⊞PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helices: 0
• ⊞⊞DeepLocPro: Extracellular
  • Cytoplasmic Score: 0.0003
  • Cytoplasmic Membrane Score: 0.0001
  • Cell wall & surface Score: 0.0005
  • Extracellular Score: 0.9991
• ⊞⊞LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular possibility: 1
  • Signal peptide possibility: -1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• ⊞⊞SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.013876
  • TAT(Tat/SPI): 0.000785
  • LIPO(Sec/SPII): 0.002522
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 15926124 NCBI
• RefSeq: NP_373657 NCBI
• UniProt: A0A0H3JSY1 UniProt

⊟Protein sequence

• MKDKYKIDPGIIKNNTEETTAISKISYEVENANLYGADSEDITRQIEYLKAKKKFPSNLEYVDSYTDSLNGVTTSAFLNKDTGKVTLGMTGTNIQGEAFKKLKEGEFSRQNVTNALETVKDGYADLKILYSPASDQNYRYANTQEFINKIKSKYDIDFITGHSLGGRDAVVLGMSNGIPNIVVYNPAPISINSLNPNSPDGKRLLELYKNYKGNITRFVAENDALTENLKKYKHYVFFGNDKVFKNGKGHEMEGFLTEEEQKAIKKELKKLQGYAEENNKSFVKNSNNAISKLASIELLRANMMTTNGGGLSSSQQKVLESLTALTIAQSFSQLIDDEINQIKKMYNEKKKEFGKNWEDAQKAGKAVGEDLSVNGVLNALDEGQVNESSMVREPEQMISAKERQLSTIGSSVSNYIMRVRLSINEIVDKDQVLASQIGGLL

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell: data available for COL
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: lpl9 > SA0406 > SA0407 > SA0408

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊞Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊞Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications