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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS12855 [old locus tag: SACOL2449 ]
  • pan locus tag?: SAUPAN005996000
  • symbol: SACOL_RS12855
  • pan gene symbol?: —
  • synonym:
  • product: MFS transporter

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS12855 [old locus tag: SACOL2449 ]
  • symbol: SACOL_RS12855
  • product: MFS transporter
  • replicon: chromosome
  • strand: -
  • coordinates: 2508363..2509763
  • length: 1401
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (2508363..2509763) NCBI
  • BioCyc: SACOL_RS12855 BioCyc
  • MicrobesOnline: see SACOL2449

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGACACATCAAAACAATTTAGAGGTGACAACCGATTGCTTTTGGGTATCGTTTTAGGG
    GTTATTACCTTTTGGCTATTCGCGCAGTCACTTGTTAATCTTGTTGTCCCATTACAATCA
    ACATATAGTAGTGACGTTGGAACGATAAATATCGCTGTTAGCTTATCTGCCTTATTTGCT
    GGTTTGTTTATCGTAGGTGCTGGTGATGTTGCTGATAAATTTGGTCGCGTCAAAATTACT
    TATGTAGGATTGATATTAAATGTTGTAGGTTCATTACTCATCATCATTACACCTTTGCCA
    GCATTTTTAATTATAGGTAGAATAATTCAAGGTTTGTCTGCAGCATGTATTATGCCATCA
    ACACTTGCTATTATTAACGAATATTATATTGGTACAAGAAGACAACGTGCCTTAAGCTAT
    TGGTCTATTGGTTCTTGGGGTGGTAGTGGTATTTGTACGTTGTTTGGTGGCTTAATGGCT
    ACATATATAGGTTGGCGTTCAATATTTGTTGTTTCAATTCTATTAACATTATTAGCAATG
    TACTTAATCAAACATGCACCTGAGACTAAAGCAGAACCAATCAAAGGTATGAAAGCAGAA
    GCTAAAAAGTTTGACGTTATTGGTTTAGTCATTTTAGTAGTGACGATGTTAAGTTTAAAT
    GTAATCATCACACAGACGTCTCATTTTGGTTTAGTTTCACCGTTAATTCTAGCTTTAATT
    GTTGTGTTTATCTGTTCATTAGTTGGTTTTGTATATTACGAAAATAAAATAAAGCATCCA
    CTTGTTGATTTTTCAATTTTTAAAAATAGAGGATACAGTGGTGCAACTATTTCAAACTTC
    TTATTAAATGGTGTAGCAGGTGGTGCACTTATCGTTATTAACACGTATTATCAACAACAA
    TTAGGATTTAATTCTTCGCAAACGGGTTATATTTCATTAACGTATTTAATAACAGTGTTG
    TCAATGATTCGTGTAGGTGAAAAGATTTTATCTCAACATGGTCCGAAGCGCCCACTATTA
    CTAGGAAGTGGCTTTACAGTGATTGGGTTAATCTTATTGTCGTTAACATTTTTACCAGAA
    GTGTGGTATATCATATCTAGTATAGTTGGATATTTATTGTTTGGTACTGGTTTAGGATTA
    TATGCTACACCATCAACTGATACAGCAGTTGCTAGTGCGCCAGATGATAAGTCGGGTGTT
    GCTTCAGGTGTGTATAAAATGGCGTCATCATTAGGAAATGCATTTGGAGTAGCAGTATCT
    GGTACGGTTTATACTGTGTTAGCAGCTAATTTAAATTTGAACTTAGGTGGTTTCACAGGT
    ATGATGTTTAATGCCTTGCTAGCAATTGTTGCATTTTTAGTCATTTTACTATTAGTTCCT
    AAAAATCAAACGAATTTGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1401

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS12855 [old locus tag: SACOL2449 ]
  • symbol: SACOL_RS12855
  • description: MFS transporter
  • length: 466
  • theoretical pI: 9.74613
  • theoretical MW: 49854.8
  • GRAVY: 0.845708

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Cellular processes Cellular processes Toxin production and resistance drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family (TIGR00711; HMM-score: 124.9)
    Metabolism Transport and binding proteins Other drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family (TIGR00711; HMM-score: 124.9)
    and 9 more
    multidrug resistance protein (TIGR00880; HMM-score: 61.1)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids MFS transporter, aromatic acid:H+ symporter (AAHS) family (TIGR00895; HMM-score: 47.2)
    drug resistance transporter, Bcr/CflA subfamily (TIGR00710; HMM-score: 43.4)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-galactonate transporter (TIGR00893; HMM-score: 31.4)
    Metabolism Transport and binding proteins Anions Na(+)-dependent inorganic phosphate cotransporter (TIGR00894; HMM-score: 30.4)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids MFS transporter, sialate:H+ symporter (SHS) family (TIGR00891; HMM-score: 27.4)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids phosphoglycerate transporter family protein (TIGR00881; HMM-score: 23.8)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids oxalate/formate antiporter family transporter (TIGR00890; HMM-score: 20.3)
    Metabolism Transport and binding proteins Cations and iron carrying compounds cation transport protein (TIGR00898; HMM-score: 17.1)
  • TheSEED: see SACOL2449
  • PFAM:
    MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 158.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 14
  • ⊞DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9987
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0013
  • LocateP:
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.066585
    • TAT(Tat/SPI): 0.002994
    • LIPO(Sec/SPII): 0.021327
  • predicted transmembrane helices (TMHMM): 14

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MDTSKQFRGDNRLLLGIVLGVITFWLFAQSLVNLVVPLQSTYSSDVGTINIAVSLSALFAGLFIVGAGDVADKFGRVKITYVGLILNVVGSLLIIITPLPAFLIIGRIIQGLSAACIMPSTLAIINEYYIGTRRQRALSYWSIGSWGGSGICTLFGGLMATYIGWRSIFVVSILLTLLAMYLIKHAPETKAEPIKGMKAEAKKFDVIGLVILVVTMLSLNVIITQTSHFGLVSPLILALIVVFICSLVGFVYYENKIKHPLVDFSIFKNRGYSGATISNFLLNGVAGGALIVINTYYQQQLGFNSSQTGYISLTYLITVLSMIRVGEKILSQHGPKRPLLLGSGFTVIGLILLSLTFLPEVWYIISSIVGYLLFGTGLGLYATPSTDTAVASAPDDKSGVASGVYKMASSLGNAFGVAVSGTVYTVLAANLNLNLGGFTGMMFNALLAIVAFLVILLLVPKNQTNL

⊟Experimental data[edit | edit source]

  • experimentally validated: see SACOL2449
  • protein localization: see SACOL2449
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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