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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

organism: Staphylococcus aureus N315

locus tag: SA_RS02400 [old locus tag: SA0421 ]

pan locus tag^?: SAUPAN002177000

symbol: SA_RS02400

pan gene symbol^?: metP2

synonym:
product: ABC transporter permease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

type: CDS
locus tag: SA_RS02400 [old locus tag: SA0421 ]
symbol: SA_RS02400
product: ABC transporter permease
replicon: chromosome
strand: +
coordinates: 483071..483730
length: 660
essential: no DEG other strains

⊟Accession numbers[edit | edit source]

Location: NC_002745 (483071..483730) NCBI
BioCyc: SA_RS02400 BioCyc
MicrobesOnline: see SA0421

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

1
61
121
181
241
301
361
421
481
541
601
ATGTTTGGTTCTGATTTAGACAGTGCACAGTTATTACAAGCATTGTACGAAACGTTATAT
ATGGTATCTATTGCTTTATTTTTAGGAGCAGTGATTGGTATTCCATTAGGTGTCTTATTG
GTAATTACTCGAAAACAAGGCATATGGCCCAATATAGTGATACATCAAGTTTTAAATCCT
TTAATCAATATTTTAAGGTCACTACCATTTATTATTTTGTTAATTGCGATTGTGCCATTC
ACAAAATTAGTAGTAGGTACTTCAATTGGTACGACTGCTGCCATCGTGCCTTTAACTGTA
TATGTGGCACCTTACATTGCAAGACTTGTTGAAAACTCATTATTGGAAGTAGACGAGGGG
ATTATTGAAGCGGCGAAAGCGATGGGCGCTTCACCACTACAAATCATTAGATATTTTTTA
ATTCCTGAAGCGTTAGGTTCATTAGTATTAGCAATTACCACTGCGATTATTGGACTTATT
GGAAGTACGGCGATGGCAGGAGCTGTTGGCGGTGGTGGTATAGGAGACTTAGCTTTAGTG
TATGGTTATCAAAGATTTGATACGACGGTCATTATTATTACCGTTATTGTATTAGTCATT
ATTGTCCAAGTGATTCAAACGCTAGGGAATGTCCTAGCTAGATTCATACGTAGACATTAA
60
120
180
240
300
360
420
480
540
600
660

⊟Protein[edit | edit source]

⊟General[edit | edit source]

locus tag: SA_RS02400 [old locus tag: SA0421 ]
symbol: SA_RS02400
description: ABC transporter permease
length: 219
theoretical pI: 7.66251
theoretical MW: 23309.9
GRAVY: 1.15479

⊟Function[edit | edit source]

⊞TIGRFAM:
Metabolism Transport and binding proteins Anions phosphonate ABC transporter, permease protein PhnE (TIGR01097; HMM-score: 73.4)
and 11 more
choline ABC transporter, permease protein (TIGR03416; HMM-score: 38.3)
ectoine/hydroxyectoine ABC transporter, permease protein EhuD (TIGR03003; HMM-score: 33.2)
Metabolism Transport and binding proteins Anions phosphate ABC transporter, permease protein PstA (TIGR00974; HMM-score: 31.8)
Metabolism Transport and binding proteins Amino acids, peptides and amines amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family (TIGR01726; HMM-score: 22.7)
Metabolism Transport and binding proteins Anions phosphate ABC transporter, permease protein PstC (TIGR02138; HMM-score: 21.9)
ectoine/hydroxyectoine ABC transporter, permease protein EhuC (TIGR03004; HMM-score: 20.3)
NifC-like ABC-type porter (TIGR01581; HMM-score: 19)
2-aminoethylphosphonate ABC transporter, permease protein (TIGR03226; HMM-score: 18.4)
Metabolism Transport and binding proteins Cations and iron carrying compounds nickel ABC transporter, permease subunit NikB (TIGR02789; EC 3.6.3.24; HMM-score: 18.2)
Metabolism Transport and binding proteins Anions sulfate ABC transporter, permease protein CysT (TIGR02139; HMM-score: 16.6)
Metabolism Transport and binding proteins Anions molybdate ABC transporter, permease protein (TIGR02141; HMM-score: 14.8)
TheSEED: see SA0421
⊞PFAM:
BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 71.9)
and 1 more
FtsX; FtsX-like permease C-terminal (PF02687; HMM-score: 16.1)

⊟Structure, modifications & cofactors[edit | edit source]

domains:
modifications:
cofactors:
effectors:

⊟Localization[edit | edit source]

⊞
PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 5
⊞
DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 1
- Cell wall & surface Score: 0
- Extracellular Score: 0
LocateP:
⊞
SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001296
- TAT(Tat/SPI): 0.001172
- LIPO(Sec/SPII): 0.002057
predicted transmembrane helices (TMHMM): 5

⊟Accession numbers[edit | edit source]

GI: 446390139 NCBI
RefSeq: WP_000467994 NCBI
UniProt: see SA0421

⊟Protein sequence[edit | edit source]

MFGSDLDSAQLLQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGIWPNIVIHQVLNPLINILRSLPFIILLIAIVPFTKLVVGTSIGTTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGSTAMAGAVGGGGIGDLALVYGYQRFDTTVIIITVIVLVIIVQVIQTLGNVLARFIRRH

⊟Experimental data[edit | edit source]

experimentally validated: data available for COL, NCTC8325
protein localization: data available for COL
quantitative data / protein copy number per cell:
interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

regulator: CymR* see SA0421

⊟Transcription pattern[edit | edit source]

S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

Aureolib: no data available

⊟Protein stability[edit | edit source]

half-life: no data available

⊞Biological Material[edit | edit source]

⊞Other Information[edit | edit source]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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