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⊟Summary[edit | edit source]
- pan ID?: SAUPAN002177000
- symbol?: metP2
- synonym:
- description?: ABC transporter permease
- ABC transporter permease
- methionine ABC transporter permease
- methionine uptake ABC transporter, permease
- D-methionine transport system permease protein metI
- ABC transporter ATP-binding protein
- binding--dependent transport system inner membrane component family protein
- binding-protein-dependent transport system inner membrane protein
- metal ion ABC superfamily ATP binding cassette transporter, membrane protein
- Methionine ABC transporter permease protein
- putative transport system membrane protein
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 2681462..2682121
- synteny block?: BlockID0014780
- occurrence?: in 97% of 34 strains
gmpB (metP2) : glycylmethionine import permease [1]
• Staphylococcus aureus produces two highly-similar methionine import-like ABC transporters with different substrate specificities. This version is specific for glycylmethionine dipeptides. The other version transports methionine.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0438
08BA02176:
C248_0512
11819-97:
MS7_0436
6850:
RSAU_000395
71193:
ST398NM01_0528
ECT-R 2:
ECTR2_396
ED133:
SAOV_0480
ED98:
SAAV_0405
HO 5096 0412:
SAEMRSA15_03880
JH1:
SaurJH1_0497
JH9:
SaurJH9_0484
JKD6008:
SAA6008_00466
JKD6159:
SAA6159_00412
JSNZ:
JSNZ_000395
LGA251:
SARLGA251_03960
M013:
M013TW_0427
MRSA252:
SAR0462
MSHR1132:
SAMSHR1132_04070
MSSA476:
SAS0420
Mu3:
SAHV_0460
Mu50:
SAV0463
MW2:
MW0417
RF122:
SAB0412
ST398:
SAPIG0528
T0131:
SAT0131_00502
TCH60:
HMPREF0772_10060 (metI)
TW20:
SATW20_05310
USA300_TCH1516:
—
VC40:
SAVC_01900
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MFGSDLDSAQLLQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGIWPNIVIHQVLNP
N315 MFGSDLDSAQLLQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGIWPNIVIHQVLNP
NCTC8325 MFGSDLDSAQLLQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGIWPNIVIHQVLNP
Newman MFGSDLDSAQLLQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGIWPNIVIHQVLNP
USA300_FPR3757 MFGSDLDSAQLLQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGIWPNIVIHQVLNP
************************************************************
COL LINILRSLPFIILLIAIVPFTKLVVGTSIGTTAAIVPLTVYVAPYIARLVENSLLEVDEG
N315 LINILRSLPFIILLIAIVPFTKLVVGTSIGTTAAIVPLTVYVAPYIARLVENSLLEVDEG
NCTC8325 LINILRSLPFIILLIAIVPFTKLVVGTSIGTTAAIVPLTVYVAPYIARLVENSLLEVDEG
Newman LINILRSLPFIILLIAIVPFTKLVVGTSIGTTAAIVPLTVYVAPYIARLVENSLLEVDEG
USA300_FPR3757 LINILRSLPFIILLIAIVPFTKLVVGTSIGTTAAIVPLTVYVAPYIARLVENSLLEVDEG
************************************************************
COL IIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGSTAMAGAVGGGGIGDLALV
N315 IIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGSTAMAGAVGGGGIGDLALV
NCTC8325 IIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGSTAMAGAVGGGGIGDLALV
Newman IIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGSTAMAGAVGGGGIGDLALV
USA300_FPR3757 IIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGSTAMAGAVGGGGIGDLALV
************************************************************
COL YGYQRFDTTVIIITVIVLVIIVQVIQTLGNVLARFIRRH
N315 YGYQRFDTTVIIITVIVLVIIVQVIQTLGNVLARFIRRH
NCTC8325 YGYQRFDTTVIIITVIVLVIIVQVIQTLGNVLARFIRRH
Newman YGYQRFDTTVIIITVIVLVIIVQVIQTLGNVLARFIRRH
USA300_FPR3757 YGYQRFDTTVIIITVIVLVIIVQVIQTLGNVLARFIRRH
***************************************
- ↑ Wade A Williams, Rong-gaung Zhang, Min Zhou, Grazyna Joachimiak, Piotr Gornicki, Dominique Missiakas, Andrzej Joachimiak
The membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus binds the dipeptide GlyMet via side chain interactions.
Biochemistry: 2004, 43(51);16193-202
[PubMed:15610013] [WorldCat.org] [DOI] (P p)