PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS13485 [old locus tag: SA2354 ]
• pan locus tag^?: SAUPAN006232000
• symbol: SA_RS13485
• pan gene symbol^?: oatA
• synonym:
• product: O-acetyltransferase OatA

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS13485 [old locus tag: SA2354 ]
• symbol: SA_RS13485
• product: O-acetyltransferase OatA
• replicon: chromosome
• strand: -
• coordinates: 2645038..2646849
• length: 1812
• essential: no DEG other strains

⊟Accession numbers

• Location: NC_002745 (2645038..2646849) NCBI
• BioCyc: SA_RS13485 BioCyc
• MicrobesOnline: see SA2354

⊟Phenotype

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⊟DNA sequence

• 1
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  1801
  
  ATGGATACAAAAGACTTTAAACGTTTAGAAAAAATGTATTCCCCGCGATACTTACCCGGA
  TTAGATGGATTGAGGGCATTCGCAGTTATAGGAATCATTATTTATCACTTGAATGCACAA
  TGGTTAAGTGGGGGCTTTTTAGGAGTAGATACATTCTTCGTTATTTCAGGTTATTTAATA
  ACAAGTTTGTTGATAAGTGAGTATTATCGGACGCAAAAAATCGATTTGCTAGAGTTTTGG
  AAGCGACGATTGAAACGACTCATTCCGGCAGTGTTATTTTTAATCTGTGTCGTGCTTACG
  TTCACACTGATATTTAAACCGGAATTGATTATACAAATGAAACGAGATGCTATTGCAGCT
  ATATTCTATGTTTCAAACTGGTGGTACATTTCACAGAATGTAGATTATTTTAACCAATTT
  GCTATTGAACCACTCAAACATTTATGGTCTTTAGCCATTGAAGAACAATTTTACTTGCTT
  TTCCCATTGGTTATCACGTTCTTATTACATAGATTTAAACCGAGAAATATTATTCAAACG
  CTATTTATTGTATCGTTGATTTCTTTAGGACTTATGATAGTGATTCATTTCATCACTGGA
  GATAATTCACGTGTGTATTTTGGGACAGATACACGACTGCAAACTTTATTGCTTGGTTGT
  ATATTAGCATTTATTTGGCCTCCGTTTGCTTTGAAAAAAGATATTTCTAAAAAGATTGTC
  GTATCATTAGATATTATAGGGATATCTGGTTTTGCGGTTCTAATGACTTTGTTCTTTATA
  GTTGGCGACCAAGATCAATGGATCTATAATGGAGGATTTTACATTATATCATTTGCAACT
  TTATTCATTATTGCAATTGCGGTACATCCTTCTAGTTTATTTGCTAAATTTTTAAGTATG
  AAACCTTTACTAATTATAGGTAAACGATCATATAGCTTATATTTATGGCATTATCCTATC
  ATTGTTTTTGTGAACAGTTATTACGTACAAGGACAAATACCGGTATACGTTTATATTATA
  GAAATTTTGTTAACAGCGTTAATGGCTGAAATTTCGTATCGCTTTATTGAAACACCTATA
  CGTAAAAAAGGATTTAAAGCTTTTGCATTTTTACCTAAAAAGAAGGGGCAATTTGCTAGA
  ACAGTGTTAGTTATCCTATTATTGGTTCCGTCTATCGTTGTGCTCAGTGGACAGTTTGAT
  GCACTTGGCAAACAACATGAAGCCGAGAAGAAAGAGAAGAAGACGGAATTTAAAACAACG
  AAGAAAAAAGTCGTTAAAAAAGATAAGCAAGAGGATAAGCAGACAGCGAATAGCAAAGAG
  GATATTAAAAAGTCATCACCACTATTAATTGGTGACTCGGTCATGGTGGATATTGGTAAT
  GTCTTTACTAAGAAAATACCAAATGCACAAATTGATGGTAAAGTTGGACGGCAACTCGTT
  GATGCTACACCAATTGTGAAATCGCAATATAAAGACTATGCTAAAAAAGGTCAAAAAGTT
  GTAGTAGAGCTTGGTACAAATGGGGCATTTACGAAAGATCAATTAAATGAACTATTGGAT
  AGTTTTGGAAAAGCAGACATATATTTAGTTTCTATTAGAGTACCTAGAGATTATGAAGGT
  AGAATAAATAAATTAATTTATGAGGCAGCTGAAAAGCGCTCTAATGTACATCTAGTCGAT
  TGGTATAAAGCTTCTGCAGGTCATCCGGAATACTTTGCATATGACGGTATTCACTTAGAA
  TATGCAGGTAGTAAAGCGCTGACTGATTTGATTGTAAAAACGATGGAAACACATGCTACA
  AATAAGAAATAA
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  1812
  

⊟Protein

⊟General

• locus tag: SA_RS13485 [old locus tag: SA2354 ]
• symbol: SA_RS13485
• description: O-acetyltransferase OatA
• length: 603
• theoretical pI: 10.0029
• theoretical MW: 69098.1
• GRAVY: 0.222554

⊟Function

• reaction:
  EC 2.3.1.-?  ExPASy
• TIGRFAM:
  Cellular processes Cellular processes Sporulation and germination stage III sporulation protein AF (TIGR02896; HMM-score: 5.1)
• TheSEED: see SA2354
• PFAM:
  Acyl_transf_3 (CL0316) Acyl_transf_3; Acyltransferase family (PF01757; HMM-score: 93.7)
  and 2 more
  SGNH_hydrolase (CL0264) Lipase_GDSL_2; GDSL-like Lipase/Acylhydrolase family (PF13472; HMM-score: 16.9)
  no clan defined DisA-linker; DisA bacterial checkpoint controller linker region (PF10635; HMM-score: 12.5)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 11
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.002962
  • TAT(Tat/SPI): 0.000138
  • LIPO(Sec/SPII): 0.001129
• predicted transmembrane helices (TMHMM): 11

⊟Accession numbers

• GI: 446301966 NCBI
• RefSeq: WP_000379821 NCBI
• UniProt: see SA2354

⊟Protein sequence

• MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSGGFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFTLIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLLFPLVITFLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLLGCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYIISFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIPVYVYIIEILLTALMAEISYRFIETPIRKKGFKAFAFLPKKKGQFARTVLVILLLVPSIVVLSGQFDALGKQHEAEKKEKKTEFKTTKKKVVKKDKQEDKQTANSKEDIKKSSPLLIGDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNGAFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASAGHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications