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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS12380 [old locus tag: SA2156 ]
  • pan locus tag?: SAUPAN005878000
  • symbol: SA_RS12380
  • pan gene symbol?: lctP2
  • synonym:
  • product: L-lactate permease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS12380 [old locus tag: SA2156 ]
  • symbol: SA_RS12380
  • product: L-lactate permease
  • replicon: chromosome
  • strand: -
  • coordinates: 2421937..2423535
  • length: 1599
  • essential: yes DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (2421937..2423535) NCBI
  • BioCyc: SA_RS12380 BioCyc
  • MicrobesOnline: see SA2156

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
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    ATGTTAGTAAATACGTTTAACCCATTTGATAATTTATTATTATCGTCTTTAATTGCAGCA
    ATACCGATTGTACTGTTTTTACTATGTTTAACTGTTTTTAAAATGAAAGGTATTTATGCA
    GCTATTACAACACTTGTTGTAACATTACTAATTGCAATACCATTTTTCAAATTGCCAGTT
    GGTATCGCTTCTGGTGCAGTAGTCGAAGGTTTCTTCCAAGGTATCATTCCGATTGGCTAT
    ATCGTTATGATGGCAGTATTGTTATACAAAATTACTGTTGAATCTGGACAATTTTTAACA
    ATTCAAGATAGTATTACAAATATTTCACAAGACCAACGTATTCAAGTTTTACTTATTGGA
    TTTGCATTCAACGCATTTTTAGAAGGTGCAGCAGGATTTGGTGTACCAATTGCAATTTGT
    GCACTTTTATTAACACAATTAGGATTTAATCCATTAAAAGCTGCGATGTTATGTTTAGTC
    GCAAATGCAGCGTCTGGTGCTTTTGGTGCGATTGGTATCCCTGTAGGTGTTGTAGAAACG
    TTGAAATTACCTGGAGATGTTTCAGTATTAGGTGTTTCTCAATCAGCAACTTTAACATTG
    GCAATCATAAATTTCATTATTCCATTCTTACTTATCTTTATTATTGATGGTTTTAGAGGT
    GTTAAAGAAACATTACCAGCAATTTTAGTAGTTTCAATCACTTATACACTTACTCAAGGA
    TTATTAACTGTATTCAGTGGACCTGAATTAGCAGATATTATTCCACCGTTATTAACAATG
    TTAGCATTAGCAGTATTTTCTAAAAAATTCCAACCAAAACACATTTATCGTGTTAATAAA
    GATGAAGAAATTGAACCTGCAAAAGCACATTCTGCAAAAGCAGTATTACATGCATGGAGC
    CCATTCATTGTATTAACAGTCATTGTAATGATTTGGAGTGCGCCATTCTTTAAAAACTTA
    TTCTTACCAAATGGTGCTTTATCATCATTAGTATTTAAATTCAACTTACCTGGAACAATC
    AGCGAAGTTACGCATAAACCATTAGTATTGACTTTAAATATTATTGGACAAACAGGTACA
    GCTATTTTATTAACTATTATTATTACAATTTTAATGTCTAAAAAGGTTAACTTTAAAGAT
    GCTGTTAGATTATTCGGCGTTACATTTAAAGAGTTGTGGTTACCAGTTCTTACAATTTGT
    TTCATCTTAGCAATCTCTAAAATCACAACTTATGGTGGTTTAAGTGCAGCAATGGGTCAA
    GGTATAGCTAAAGCAGGTAATGTCTTCCCAGTTCTATCACCAATCTTAGGTTGGATAGGT
    GTGTTTATGACAGGATCAGTTGTAAATAACAATTCATTATTTGCACCAATTCAAGCTTCT
    GTTGCACAACAAATTGGAACAAGTGGTTCACTTCTTGTATCTGCTAATACAGTTGGTGGT
    GTAGCGGCAAAATTGATTTCACCACAATCAATTGCAATTGCAACTGCAGCAGTAAAACAA
    GTTGGTAAGGAATCAGAATTATTAAAAATGACATTGAAATACAGTGTATGTTTACTAATA
    TTCATCTGTATTTGGACTTTCATCTTGTCATTATTATAA
    60
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⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS12380 [old locus tag: SA2156 ]
  • symbol: SA_RS12380
  • description: L-lactate permease
  • length: 532
  • theoretical pI: 9.63197
  • theoretical MW: 56683.9
  • GRAVY: 1.02575

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids transporter, lactate permease (LctP) family (TIGR00795; HMM-score: 529.2)
  • TheSEED: see SA2156
  • PFAM:
    IT (CL0182) Lactate_perm; L-lactate permease (PF02652; HMM-score: 534.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 13
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002225
    • TAT(Tat/SPI): 0.000303
    • LIPO(Sec/SPII): 0.002796
  • predicted transmembrane helices (TMHMM): 13

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MLVNTFNPFDNLLLSSLIAAIPIVLFLLCLTVFKMKGIYAAITTLVVTLLIAIPFFKLPVGIASGAVVEGFFQGIIPIGYIVMMAVLLYKITVESGQFLTIQDSITNISQDQRIQVLLIGFAFNAFLEGAAGFGVPIAICALLLTQLGFNPLKAAMLCLVANAASGAFGAIGIPVGVVETLKLPGDVSVLGVSQSATLTLAIINFIIPFLLIFIIDGFRGVKETLPAILVVSITYTLTQGLLTVFSGPELADIIPPLLTMLALAVFSKKFQPKHIYRVNKDEEIEPAKAHSAKAVLHAWSPFIVLTVIVMIWSAPFFKNLFLPNGALSSLVFKFNLPGTISEVTHKPLVLTLNIIGQTGTAILLTIIITILMSKKVNFKDAVRLFGVTFKELWLPVLTICFILAISKITTYGGLSAAMGQGIAKAGNVFPVLSPILGWIGVFMTGSVVNNNSLFAPIQASVAQQIGTSGSLLVSANTVGGVAAKLISPQSIAIATAAVKQVGKESELLKMTLKYSVCLLIFICIWTFILSLL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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