PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS11110 [old locus tag: SA1934 ]
• pan locus tag^?: SAUPAN005428000
• symbol: SA_RS11110
• pan gene symbol^?: —
• synonym:
• product: ATP-grasp domain-containing protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS11110 [old locus tag: SA1934 ]
• symbol: SA_RS11110
• product: ATP-grasp domain-containing protein
• replicon: chromosome
• strand: -
• coordinates: 2183672..2184865
• length: 1194
• essential: no DEG other strains

⊟Accession numbers

• Location: NC_002745 (2183672..2184865) NCBI
• BioCyc: SA_RS11110 BioCyc
• MicrobesOnline: see SA1934

⊟Phenotype

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⊟DNA sequence

• 1
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  1141
  
  ATGACAAATAATGGTAATGAGCCGAACTTAACGTTAAGTGATTTATATGACAAAGATGTT
  GTCTATACGTCAAGACCTTCGTATATATCGAATCCATGGTTGAAACCGGACGAACATCAA
  TCTAATTTTTTAACTGGTAGGGAGTTATTAATAGCAAATCAATTACCTGTTATTGTTCAC
  GAAGCTAGTGCGACAGACAAATTGCATCAGCTATTTCAAGTTATTGGTAAGGAAGTACCG
  AACTCAATTTTTACATTTAACAATCAGCAATCTTACGAAAACTTGATCAAACAATTGGCA
  CATAAGGAAAATAAAAAGATTTATTTTCAATATATTCATGATGAAACAATCTTGAATCAG
  CAATATTATGCATTAGATAAAACGTTATTTGTTGCTTTAAATAATAAAGCAAGAATACCT
  GAATGGACAAATGGGAAGTTTTTACCAAAAAGAAAAGTTGTAAAAATTGAGCAATTCGAA
  AACGAGATTAAGAATTGGGAATTCCCGTTAGTAATTAAGCCGGGAGATGATCTTCCGACA
  GCAGGTGGCTATGGCGTTATGATTTGTTATCATGATGCAGATTTACAAAAAGCGATAACG
  CGTATTAAAGAGGCAACTGCTGAAACGAATTCGCTTATTATCGAACAGAAGATTGAAGAA
  AAAGCGAATTATTGCGTTCAGTTTGCATACTCGGAATCGCTAGGCATTCAATATCTTGGT
  GCGGCAACGCAATTAACGGATAAGTACGGATTTTATAACGGAAATGAAAATACTACTAAT
  GTACCAGAGCACGTTATAGAAGCAGGTAGACAAATTATGGAAAACGGTGTGAATCAAGGA
  TTCTTTGGTGTAGCTGGTTTTGACCTACTCGTCGATGAGGATGATAACGTTTATGCGATT
  GATTTAAACTTTAGACAAAATGGTTCAACGAGCATGTTATTACTTGCTAACGAGTTGAAT
  TCAGGATATCAAAAGTTTTATAGTTATCATTCAAAAGGTGATAACACACATTTCTTCAAT
  ACGATTTTGAAATATGTCAAAGAAGGTAGTTTATACCCGTTATCTTATTATGATGGTGAT
  TGGTACGGTGAAGATAAAGTTAAATCAAGGTTTGGCTGTATTTGGCATGGTGATTCAAAA
  GAAACAGTACTGGAGAATGAACGCGCATTTTTAGCTGAACTTGAACACTATTAG
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  1194
  

⊟Protein

⊟General

• locus tag: SA_RS11110 [old locus tag: SA1934 ]
• symbol: SA_RS11110
• description: ATP-grasp domain-containing protein
• length: 397
• theoretical pI: 4.91145
• theoretical MW: 45629.7
• GRAVY: -0.527456

⊟Function

• TIGRFAM:
  Metabolism Fatty acid and phospholipid metabolism Biosynthesis acetyl-CoA carboxylase, biotin carboxylase subunit (TIGR00514; EC 6.3.4.14; HMM-score: 11.1)
  UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing (TIGR03568; EC 3.1.4.-,5.1.3.-; HMM-score: 9.8)
• TheSEED: see SA1934
• PFAM:
  ATP-grasp (CL0179) ATP-grasp_4; ATP-grasp domain (PF13535; HMM-score: 18.9)
  ATP-grasp_3; ATP-grasp domain (PF02655; HMM-score: 18.4)
  and 4 more
  no clan defined DUF3182; Protein of unknown function (DUF3182) (PF11379; HMM-score: 14.9)
  Peptidase_CA (CL0125) Peptidase_C101; Peptidase family C101 (PF16218; HMM-score: 14.9)
  Bet_v_1_like (CL0209) START_2; START-like superfamily domain (PF19569; HMM-score: 13.8)
  ATP-grasp (CL0179) CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain (PF02786; HMM-score: 13.5)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.7285
  • Cytoplasmic Membrane Score: 0.0406
  • Cell wall & surface Score: 0.0022
  • Extracellular Score: 0.2287
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.004537
  • TAT(Tat/SPI): 0.000646
  • LIPO(Sec/SPII): 0.000764
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446105862 NCBI
• RefSeq: WP_000183717 NCBI
• UniProt: see SA1934

⊟Protein sequence

• MTNNGNEPNLTLSDLYDKDVVYTSRPSYISNPWLKPDEHQSNFLTGRELLIANQLPVIVHEASATDKLHQLFQVIGKEVPNSIFTFNNQQSYENLIKQLAHKENKKIYFQYIHDETILNQQYYALDKTLFVALNNKARIPEWTNGKFLPKRKVVKIEQFENEIKNWEFPLVIKPGDDLPTAGGYGVMICYHDADLQKAITRIKEATAETNSLIIEQKIEEKANYCVQFAYSESLGIQYLGAATQLTDKYGFYNGNENTTNVPEHVIEAGRQIMENGVNQGFFGVAGFDLLVDEDDNVYAIDLNFRQNGSTSMLLLANELNSGYQKFYSYHSKGDNTHFFNTILKYVKEGSLYPLSYYDGDWYGEDKVKSRFGCIWHGDSKETVLENERAFLAELEHY

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell: data available for COL
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator: CodY see SA1934

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications