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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS08640 [old locus tag: SA1535 ]
  • pan locus tag?: SAUPAN004365000
  • symbol: SA_RS08640
  • pan gene symbol?: tpx
  • synonym:
  • product: 2-Cys peroxiredoxin

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS08640 [old locus tag: SA1535 ]
  • symbol: SA_RS08640
  • product: 2-Cys peroxiredoxin
  • replicon: chromosome
  • strand: -
  • coordinates: 1754240..1754734
  • length: 495
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (1754240..1754734) NCBI
  • BioCyc: SA_RS08640 BioCyc
  • MicrobesOnline: see SA1535

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGACTGAAATAACATTCAAAGGTGGACCAATCCACTTAAAAGGTCAACAAATTAATGAA
    GGTGATTTTGCACCTGATTTTACAGTGTTAGATAATGACTTAAATCAAGTAACATTAGCA
    GATTATGCTGGTAAAAAGAAATTAATTAGTGTGGTACCATCAATTGATACAGGTGTTTGT
    GATCAGCAGACTCGCAAATTCAACTCTGAAGCTTCTAAAGAAGAGGGGATTGTGCTTACA
    ATTTCAGCAGACTTACCATTCGCACAAAAAAGATGGTGCGCTTCAGCAGGTTTAGACAAT
    GTCATTACATTAAGTGACCACCGTGACTTATCATTTGGTGAAAACTATGGCGTTGTTATG
    GAAGAACTTCGCTTATTAGCTCGTGCAGTATTTGTATTAGATGTAGATAATAAAGTTGTT
    TATAAAGAAATCGTTAGTGAAGGTACTGATTTCCCAGATTTTGATGCTGCTTTAGCTGCA
    TACAAAAATATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    495

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS08640 [old locus tag: SA1535 ]
  • symbol: SA_RS08640
  • description: 2-Cys peroxiredoxin
  • length: 164
  • theoretical pI: 4.34422
  • theoretical MW: 18047.3
  • GRAVY: -0.119512

⊟Function[edit | edit source]

  • reaction:
    EC 1.11.1.15?  ExPASy
    Peroxiredoxin 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH
  • TIGRFAM:
    Cellular processes Cellular processes Detoxification peroxiredoxin (TIGR03137; EC 1.11.1.15; HMM-score: 24.9)
    Cellular processes Cellular processes Adaptations to atypical conditions peroxiredoxin (TIGR03137; EC 1.11.1.15; HMM-score: 24.9)
  • TheSEED: see SA1535
  • PFAM:
    Thioredoxin (CL0172) Redoxin; Redoxin (PF08534; HMM-score: 88.8)
    and 1 more
    AhpC-TSA; AhpC/TSA family (PF00578; HMM-score: 63.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003082
    • TAT(Tat/SPI): 0.000174
    • LIPO(Sec/SPII): 0.000481
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTEITFKGGPIHLKGQQINEGDFAPDFTVLDNDLNQVTLADYAGKKKLISVVPSIDTGVCDQQTRKFNSEASKEEGIVLTISADLPFAQKRWCASAGLDNVITLSDHRDLSFGENYGVVMEELRLLARAVFVLDVDNKVVYKEIVSEGTDFPDFDAALAAYKNI

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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