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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS07100 [old locus tag: SA1252 ]
  • pan locus tag?: SAUPAN003844000
  • symbol: SA_RS07100
  • pan gene symbol?: —
  • synonym:
  • product: N-acetyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS07100 [old locus tag: SA1252 ]
  • symbol: SA_RS07100
  • product: N-acetyltransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 1426688..1427197
  • length: 510
  • essential: yes [1] DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (1426688..1427197) NCBI
  • BioCyc: SA_RS07100 BioCyc
  • MicrobesOnline: see SA1252

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGATCCGTCTAGGTAAAATGTCAGATTTAGATCAAATCTTAAATCTAGTAGAAGAAGCA
    AAAGAATTAATGAAAGAACACGACAACGAGCAATGGGACGATCAGTACCCACTTTTAGAA
    CATTTTGAAGAAGATATTGCTAAAGATTATTTGTACGTATTAGAGGAAAATGACAAAATT
    TATGGCTTTATTGTTGTCGACCAAGACCAAGCAGAATGGTATGATGACATTGACTGGCCA
    GTAAATAGAGAAGGCGCCTTTGTTATTCATCGATTAACTGGTTCGAAAGAATATAAAGGA
    GCTGCTACAGAATTATTCAATTATGTTATTGATGTAGTTAAAGCACGTGGTGCAGAAGTT
    ATTTTAACGGACACCTTTGCGTTAAACAAACCTGCACAAGGTTTATTTGCGAAATTTGGA
    TTTCATAAGGTCGGTGAACAATTAATGGAATATCCGCCATATGATAAAGGTGAACCATTT
    TATGCATATTATAAAAATTTAAAAGAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    510

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS07100 [old locus tag: SA1252 ]
  • symbol: SA_RS07100
  • description: N-acetyltransferase
  • length: 169
  • theoretical pI: 4.24871
  • theoretical MW: 19846.2
  • GRAVY: -0.540237

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 24.2)
  • TheSEED: see SA1252
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 42.7)
    Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 40.9)
    and 6 more
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 27.5)
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 21.4)
    Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 18.9)
    Acetyltransf_8; Acetyltransferase (GNAT) domain (PF13523; HMM-score: 15)
    FR47; FR47-like protein (PF08445; HMM-score: 13.7)
    no clan defined DUF5071; Domain of unknown function (DUF5071) (PF16804; HMM-score: 10.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001472
    • TAT(Tat/SPI): 0.000162
    • LIPO(Sec/SPII): 0.000177
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIRLGKMSDLDQILNLVEEAKELMKEHDNEQWDDQYPLLEHFEEDIAKDYLYVLEENDKIYGFIVVDQDQAEWYDDIDWPVNREGAFVIHRLTGSKEYKGAATELFNYVIDVVKARGAEVILTDTFALNKPAQGLFAKFGFHKVGEQLMEYPPYDKGEPFYAYYKNLKE

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ R Allyn Forsyth, Robert J Haselbeck, Kari L Ohlsen, Robert T Yamamoto, Howard Xu, John D Trawick, Daniel Wall, Liangsu Wang, Vickie Brown-Driver, Jamie M Froelich, Kedar G C, Paula King, Melissa McCarthy, Cheryl Malone, Brian Misiner, David Robbins, Zehui Tan, Zhan-yang Zhu Zy, Grant Carr, Deborah A Mosca, Carlos Zamudio, J Gordon Foulkes, Judith W Zyskind
    A genome-wide strategy for the identification of essential genes in Staphylococcus aureus.
    Mol Microbiol: 2002, 43(6);1387-400
    [PubMed:11952893] [WorldCat.org] [DOI] (P p)

⊟Relevant publications[edit | edit source]

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