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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

organism: Staphylococcus aureus USA300_FPR3757
locus tag: SAUSA300_RS12780 [old locus tag: SAUSA300_2313 ]
pan locus tag^?: SAUPAN005878000
symbol: SAUSA300_RS12780
pan gene symbol^?: lctP2
synonym:
product: L-lactate permease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

type: CDS
locus tag: SAUSA300_RS12780 [old locus tag: SAUSA300_2313 ]
symbol: SAUSA300_RS12780
product: L-lactate permease
replicon: chromosome
strand: -
coordinates: 2485913..2487511
length: 1599
essential: unknown other strains

⊟Accession numbers[edit | edit source]

Location: NC_007793 (2485913..2487511) NCBI
BioCyc: SAUSA300_RS12780 BioCyc
MicrobesOnline: see SAUSA300_2313

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

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ATGTTAGTAAATACGTTTAACCCATTTGATAATTTATTATTATCGTCTTTAATTGCAGCA
ATACCGATTGTACTGTTTTTACTATGTTTAACTGTTTTTAAAATGAAAGGTATTTATGCA
GCTATTACAACACTTGTTGTAACATTACTAATTGCAATACCATTTTTCAAATTGCCAGTT
GGTATCGCTTCTGGTGCAGTAGTCGAAGGTTTCTTCCAAGGTATCATTCCGATTGGCTAT
ATCGTTATGATGGCAGTATTGTTATACAAAATTACTGTTGAATCTGGACAATTTTTAACA
ATTCAAGATAGTATTACAAATATTTCACAAGACCAACGTATTCAAGTTTTACTTATTGGA
TTTGCATTCAACGCATTTTTAGAAGGTGCAGCAGGATTTGGTGTACCAATTGCAATTTGT
GCACTTTTATTAACACAATTAGGATTTAATCCATTAAAAGCTGCGATGTTATGTTTAGTC
GCAAATGCAGCGTCTGGTGCTTTTGGTGCGATTGGTATCCCTGTAGGTGTTGTAGAAACG
TTGAAATTACCTGGAGATGTTTCAGTATTAGGTGTTTCTCAATCAGCAACTTTAACATTG
GCAATCATAAATTTCATTATTCCATTCTTACTTATCTTTATTATTGATGGTTTTAGAGGT
GTTAAAGAAACATTACCAGCAATTTTAGTAGTTTCAATCACTTATACATTTACTCAAGGA
TTATTAACTGTATTCAGTGGACCTGAATTAGCAGATATTATTCCACCGTTATTAACAATG
TTAGCATTAGCAGTATTTTCTAAAAAATTCCAACCAAAACACATTTATCGTGTTAATAAA
GATGAAGAAATTGAACCTGCAAAAGCACATTCTGCAAAAGCAGTATTACATGCATGGAGC
CCATTCATTGTATTAACAGTCATTGTAATGATTTGGAGTGCGCCATTCTTTAAAAACTTA
TTCTTACCAAATGGTGCTTTATCATCATTAGTATTTAAATTCAACTTACCTGGAACAATC
AGCGAAGTTACGCATAAACCATTAGTATTGACTTTAAATATTATTGGACAAACAGGTACA
GCTATTTTATTAACTATTATTATTACAATTTTAATGTCTAAAAAGGTTAACTTTAAAGAT
GCAGGTAGATTATTCGGCGTTACATTTAAAGAGTTGTGGTTACCAGTTCTTACAATTTGT
TTCATCTTAGCAATTTCTAAAATCACAACTTATGGTGGTTTAAGTGCAGCAATGGGTCAA
GGTATTGCTAAAGCAGGTAATGTCTTCCCAGTTCTATCACCAATTTTAGGTTGGATAGGT
GTGTTTATGACAGGATCAGTTGTAAATAACAACTCATTATTTGCACCAATTCAAGCTTCT
GTTGCACAACAAATTGGAACAAGTGGTTCACTTCTTGTATCTGCTAATACAGTTGGTGGT
GTAGCGGCAAAATTGATTTCACCACAATCAATTGCAATTGCAACTGCAGCAGTAAAACAA
GTTGGTAAGGAATCAGAATTATTAAAAATGACATTGAAATACAGTGTATGTTTACTAATA
TTCATCTGTATTTGGACTTTCATCTTGTCATTATTATAA
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⊟Protein[edit | edit source]

⊟General[edit | edit source]

locus tag: SAUSA300_RS12780 [old locus tag: SAUSA300_2313 ]
symbol: SAUSA300_RS12780
description: L-lactate permease
length: 532
theoretical pI: 9.63197
theoretical MW: 56675.8
GRAVY: 1.01523

⊟Function[edit | edit source]

TIGRFAM:
Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids transporter, lactate permease (LctP) family (TIGR00795; HMM-score: 525.7)
TheSEED: see SAUSA300_2313
PFAM:
IT (CL0182) Lactate_perm; L-lactate permease (PF02652; HMM-score: 533.7)

⊟Structure, modifications & cofactors[edit | edit source]

domains:
modifications:
cofactors:
effectors:

⊟Localization[edit | edit source]

PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 13
LocateP:
SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.002225
- TAT(Tat/SPI): 0.000303
- LIPO(Sec/SPII): 0.002796
predicted transmembrane helices (TMHMM): 13

⊟Accession numbers[edit | edit source]

GI: 446883596 NCBI
RefSeq: WP_000960852 NCBI
UniProt: see SAUSA300_2313

⊟Protein sequence[edit | edit source]

MLVNTFNPFDNLLLSSLIAAIPIVLFLLCLTVFKMKGIYAAITTLVVTLLIAIPFFKLPVGIASGAVVEGFFQGIIPIGYIVMMAVLLYKITVESGQFLTIQDSITNISQDQRIQVLLIGFAFNAFLEGAAGFGVPIAICALLLTQLGFNPLKAAMLCLVANAASGAFGAIGIPVGVVETLKLPGDVSVLGVSQSATLTLAIINFIIPFLLIFIIDGFRGVKETLPAILVVSITYTFTQGLLTVFSGPELADIIPPLLTMLALAVFSKKFQPKHIYRVNKDEEIEPAKAHSAKAVLHAWSPFIVLTVIVMIWSAPFFKNLFLPNGALSSLVFKFNLPGTISEVTHKPLVLTLNIIGQTGTAILLTIIITILMSKKVNFKDAGRLFGVTFKELWLPVLTICFILAISKITTYGGLSAAMGQGIAKAGNVFPVLSPILGWIGVFMTGSVVNNNSLFAPIQASVAQQIGTSGSLLVSANTVGGVAAKLISPQSIAIATAAVKQVGKESELLKMTLKYSVCLLIFICIWTFILSLL

⊟Experimental data[edit | edit source]

experimentally validated: data available for COL, NCTC8325
protein localization: data available for COL
quantitative data / protein copy number per cell:
interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

regulator: Rex see SAUSA300_2313

⊟Transcription pattern[edit | edit source]

S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

Aureolib: no data available

⊟Protein stability[edit | edit source]

half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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