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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS08140 [old locus tag: SAUSA300_1491 ]
  • pan locus tag?: SAUPAN004107000
  • symbol: SAUSA300_RS08140
  • pan gene symbol?: pepQ2
  • synonym:
  • product: peptidase M24 family protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_RS08140 [old locus tag: SAUSA300_1491 ]
  • symbol: SAUSA300_RS08140
  • product: peptidase M24 family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1645001..1646062
  • length: 1062
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAGCAGAATAACACAAGTGCATCGTATTTTAGAACAAAAACATTTAGATGCGATTATC
    ATTCTTTCGGATTACAATAGAAGATATTTATCAGGTTTTACTGGTACCAGTGGAGCACTT
    ATCATATCTAAAGATAAACAATATTTGATAACAGACTTTAGATATATTGATCAAGCAACT
    AAGCAGGCGCCAAATTATGAAATTATTAATCGTAAATCTACTATTATTGGTGAGATTAAA
    GAATTGCTACACCAAGAAAATTTTGAAAATGTAGGTTTTGAGGGGCATCATGTAAGTTAT
    GATACATACCTTGAATTAAATAAAAGCCGTATATCATTAATAAGCATTTCTAATACTGTA
    GATAAAATTAGAGACGTCAAAGATGCTGACGAAATTGCTTTAATTCAAAAAGCAGCTAAT
    ATTGTTGATGAAACATATGAATATATTTTAACTGTTGTAAAAGCAGGCATGACTGAAAAA
    GAATTAAAGGCAATATTAGAAAGCAAAATGCTAGAATTAGGAGCAGATGGACCATCATTC
    GATACGATTGTAGCATCTGGTCATAGAGGTGCATTACCACATGGTGTTGCAAGTGATAAA
    ATTATTGAAAAAGGCGACATGATTACATTAGATTTTGGCGCGTATTATAACGGCTATTGT
    TCAGATATTACTAGAACATTTGCTATTGGAGAACCAGATCCTAAACTGAAAGAAATATAT
    CAAATAGTACTTGAATCTCAAATGAAAGCAATTAATGAGATTAGACCTGGCATGACTGGT
    GCAGAAGCTGATGCCATTTCAAGAAACTATTTAGAGTCAAAAGGGTATGGAAAAGAATTT
    GGACATTCACTAGGACATGGTATTGGTTTAGAAATCCATGAAGGGCCAATGCTGGCTCGT
    ACGATACAAGATAAACTTCAAGTTAACAACTGTGTTACAGTAGAACCTGGTGTTTATATA
    GAAGGTTTGGGCGGTATAAGAATAGAAGATGATATTTTAATTACAGAAAATGGTTGTCAA
    GTCTTTACTAAATGCACAAAAGACCTTATAGTTTTAACATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1062

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAUSA300_RS08140 [old locus tag: SAUSA300_1491 ]
  • symbol: SAUSA300_RS08140
  • description: peptidase M24 family protein
  • length: 353
  • theoretical pI: 5.06349
  • theoretical MW: 39337.6
  • GRAVY: -0.207932

Function[edit | edit source]

  • reaction:
    EC 3.4.13.9?  ExPASy
    Xaa-Pro dipeptidase Hydrolysis of Xaa-|-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-|-Pro
  • TIGRFAM:
    Genetic information processing Protein fate Protein modification and repair methionine aminopeptidase, type I (TIGR00500; EC 3.4.11.18; HMM-score: 100.5)
    and 3 more
    ectoine utilization protein EutD (TIGR02993; EC 3.-.-.-; HMM-score: 64.2)
    Genetic information processing Protein fate Protein modification and repair methionine aminopeptidase, type II (TIGR00501; EC 3.4.11.18; HMM-score: 40.1)
    Unknown function General DNA-binding protein, 42 kDa (TIGR00495; HMM-score: 15.1)
  • TheSEED: see SAUSA300_1491
  • PFAM:
    no clan defined Peptidase_M24; Metallopeptidase family M24 (PF00557; HMM-score: 232)
    and 1 more
    AMP_N-like (CL0356) Creatinase_N; Creatinase/Prolidase N-terminal domain (PF01321; HMM-score: 86.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.016788
    • TAT(Tat/SPI): 0.017013
    • LIPO(Sec/SPII): 0.001153
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MSRITQVHRILEQKHLDAIIILSDYNRRYLSGFTGTSGALIISKDKQYLITDFRYIDQATKQAPNYEIINRKSTIIGEIKELLHQENFENVGFEGHHVSYDTYLELNKSRISLISISNTVDKIRDVKDADEIALIQKAANIVDETYEYILTVVKAGMTEKELKAILESKMLELGADGPSFDTIVASGHRGALPHGVASDKIIEKGDMITLDFGAYYNGYCSDITRTFAIGEPDPKLKEIYQIVLESQMKAINEIRPGMTGAEADAISRNYLESKGYGKEFGHSLGHGIGLEIHEGPMLARTIQDKLQVNNCVTVEPGVYIEGLGGIRIEDDILITENGCQVFTKCTKDLIVLT

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]