PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus USA300_FPR3757
• locus tag: SAUSA300_RS07770 [old locus tag: SAUSA300_1424 ]
• pan locus tag^?: SAUPAN001438000
• symbol: SAUSA300_RS07770
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SAUSA300_RS07770 [old locus tag: SAUSA300_1424 ]
• symbol: SAUSA300_RS07770
• product: hypothetical protein
• replicon: chromosome
• strand: -
• coordinates: 1583418..1583975
• length: 558
• essential: unknown other strains

⊟Accession numbers

• Location: NC_007793 (1583418..1583975) NCBI
• BioCyc: SAUSA300_RS07770 BioCyc
• MicrobesOnline: see SAUSA300_1424

⊟Phenotype

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⊟DNA sequence

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  ATGAAAGCAAAAGTATTAAATAAAACTAAAGTGATTACAGGAAAAGTAAGAGCATCATAT
  GCACATATTTTTGAACCTCACAGTATGCAAGAAGGGCAAGAATCAAAGTATTCAATCAGT
  TTAATCATTCCTAAATCAGATACAAGTACGATAAAAGCCATTGAACAAGCTATAGAAGCT
  GCTAAAGAAGAAGGAAAAGTTAGTAAGTTTGGAGGCAAAGTTCCTGCAAATCTGAAACTT
  CCATTACGTGATGGAGATACTGAAAGAGAAGATGATGTCAATTATCAAGACGCTTATTTT
  ATTAACGCATCAAGCAAACAAGCACCTGGTATTATTGACCAAAACAAAATTAGATTAACG
  GATTCTGGAACTGTTGTAAGTGGTGATTATATTAGAGCTTCAATTAATCTATTTCCTTTC
  AACACAAATGGTAATAAGGGTATCGCAGTTGGATTGAACAACATTCAACTTGTAGAAAAA
  GGCGAACCTCTTGGCGGTGCAAGTGCAGCAGAAGATGATTTCGATGAATTAGACACTGAT
  GATGAGGATTTCTTATAA
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⊟Protein

⊟General

• locus tag: SAUSA300_RS07770 [old locus tag: SAUSA300_1424 ]
• symbol: SAUSA300_RS07770
• description: hypothetical protein
• length: 185
• theoretical pI: 4.6081
• theoretical MW: 20123.3
• GRAVY: -0.500541

⊟Function

• TIGRFAM:
  Genetic information processing Protein fate Protein and peptide secretion and trafficking putative PEP-CTERM system histidine kinase (TIGR02916; EC 2.7.13.3; HMM-score: 10)
  Signal transduction Signal transduction Two-component systems putative PEP-CTERM system histidine kinase (TIGR02916; EC 2.7.13.3; HMM-score: 10)
• TheSEED: see SAUSA300_1424
• PFAM:
  no clan defined DUF2815; Protein of unknown function (DUF2815) (PF10991; HMM-score: 232.5)
  and 1 more
  DUF320; Small secreted domain (DUF320) (PF03777; HMM-score: 12.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 1.78
  • Cytoplasmic Membrane Score: 8.16
  • Cellwall Score: 0.06
  • Extracellular Score: 0.01
  • Internal Helices: 0
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.008561
  • TAT(Tat/SPI): 0.000309
  • LIPO(Sec/SPII): 0.001356
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446567702 NCBI
• RefSeq: WP_000645048 NCBI
• UniProt: see SAUSA300_1424

⊟Protein sequence

• MKAKVLNKTKVITGKVRASYAHIFEPHSMQEGQESKYSISLIIPKSDTSTIKAIEQAIEAAKEEGKVSKFGGKVPANLKLPLRDGDTEREDDVNYQDAYFINASSKQAPGIIDQNKIRLTDSGTVVSGDYIRASINLFPFNTNGNKGIAVGLNNIQLVEKGEPLGGASAAEDDFDELDTDDEDFL

⊟Experimental data

• experimentally validated: data available for NCTC8325
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications