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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS05630 [old locus tag: SAUSA300_1045 ]
  • pan locus tag?: SAUPAN003385000
  • symbol: SAUSA300_RS05630
  • pan gene symbol?: uvrC
  • synonym:
  • product: excinuclease ABC subunit C

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_RS05630 [old locus tag: SAUSA300_1045 ]
  • symbol: SAUSA300_RS05630
  • product: excinuclease ABC subunit C
  • replicon: chromosome
  • strand: +
  • coordinates: 1142688..1144469
  • length: 1782
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGA
    TGCTATTTAATGAAAGATCGTAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTA
    AGAAATCGATTGCGATCATATTTTACGGGTGCTCATGATGCTAAAACAACGAGACTGGTT
    GGTGAAATACGTCGCTTTGAGTTTATTGTCACGTCAAGTGAAACAGAATCACTTTTACTG
    GAATTGAATCTGATTAAACAATATCAACCAAGATATAATATATTATTAAAGGATGATAAA
    AGTTATCCATTTATTAAAATTACGAAGGAGAAATATCCTAGACTACTAGTGACGAGAACT
    GTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGAATGCATATTCTGCTCAAGAA
    ACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
    TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTG
    AGTAAATACGCACAAATGACGAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACA
    ATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTGAATCACTTGATTTTGAACGG
    GCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTGACAAACAAACAAAAAATT
    ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGATGGATG
    TGTATCCAAGTTTTCTTTATACGACAAGGTAATATGATAAAGCGAGATACAACGATGATT
    CCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTATTGGACAATTTTATAGCTTA
    AACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGGATAAAGAAATGATT
    CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGATATGGTT
    GACCTAGCTGCACATAACGCTAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGT
    GATGAGTCCAGAACGATTAAAGCTATTGAAGAACTTGGAACACAAATGGGAATTCAAACA
    CCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCA
    ATGGTTACATTTGTCGACGGTAAACCAGATAAGAAAAATTATAGAAAGTATAAAATCAAA
    ACGGTTAAAGGTCCAGATGATTACAAATCAATGAGAGAAGTAGTAAGACGACGATATTCT
    CGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAATAGTAGATGGTGGTAAAGGA
    CATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
    GGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAA
    ATTGTACCACTGAAGAAAAATAGCCAGGCATTTTATTTGTTGCACCGTATCCAAGATGAG
    GTTCACAGATTCGCAATCACATTTCATAGACAAACACGTCAAAAGACAGGCTTGAAATCA
    ATACTTGATGATATAGATGGTATCGGTAACAAACGTAAAACATTATTATTGCGTTCATTC
    GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCT
    GAAAACGTCGCAAAGAACCTACATGAACAATTGCATAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1782

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_RS05630 [old locus tag: SAUSA300_1045 ]
  • symbol: SAUSA300_RS05630
  • description: excinuclease ABC subunit C
  • length: 593
  • theoretical pI: 9.78595
  • theoretical MW: 68670.9
  • GRAVY: -0.577234

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit C (TIGR00194; EC 3.1.25.-; HMM-score: 660.4)
    and 1 more
    group I intron endonuclease (TIGR01453; HMM-score: 13.5)
  • TheSEED: see SAUSA300_1045
  • PFAM:
    RNase_H (CL0219) UvrC_RNaseH_dom; UvrC RNAse H endonuclease domain (PF08459; HMM-score: 185.6)
    and 8 more
    UvrC_RNaseH; UvrC Ribonuclease H-like domain (PF22920; HMM-score: 90.3)
    GIY-YIG (CL0418) GIY-YIG; GIY-YIG catalytic domain (PF01541; HMM-score: 44.4)
    AAA_lid (CL0671) UVR; UvrB/uvrC motif (PF02151; HMM-score: 39.6)
    HHH (CL0198) HHH_5; Helix-hairpin-helix domain (PF14520; HMM-score: 23.3)
    GIY-YIG (CL0418) GIY_YIG_2; GIY-YIG catalytic domain (PF20815; HMM-score: 17.4)
    no clan defined MciZ; Mother cell inhibitor of FtsZ (PF13072; HMM-score: 15.4)
    HHH (CL0198) HHH_2; Helix-hairpin-helix motif (PF12826; HMM-score: 14.7)
    GIY-YIG (CL0418) GIY_YIG_domain; GIY-YIG domain-containing protein (PF19239; HMM-score: 12.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9611
    • Cytoplasmic Membrane Score: 0.0275
    • Cell wall & surface Score: 0.0023
    • Extracellular Score: 0.009
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00368
    • TAT(Tat/SPI): 0.000393
    • LIPO(Sec/SPII): 0.001302
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLLELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDKLCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKIMSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMIQSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSAMVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVAGLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSFGSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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