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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_2226 [new locus tag: SAUSA300_RS12295 ]
  • pan locus tag?: SAUPAN005736000
  • symbol: moaB
  • pan gene symbol?: moaB
  • synonym:
  • product: molybdenum cofactor biosynthesis protein B

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_2226 [new locus tag: SAUSA300_RS12295 ]
  • symbol: moaB
  • product: molybdenum cofactor biosynthesis protein B
  • replicon: chromosome
  • strand: -
  • coordinates: 2393905..2394411
  • length: 507
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGGGCGAACATCAAAACGTTAAATTGAATCGTACAGTTAAAGCAGCCGTACTAACGGTA
    TCAGATACTAGAGACTTTGATACAGATAAAGGTGGTCAATGCGTGCGCCAACTATTACAA
    GCAGATGACGTTGAAGTGAGTGACGCACATTATACAATTGTGAAAGATGAAAAAGTAGCC
    ATCACGACGCAGGTGAAGAAGTGGTTAGAAGAAGATATTGATGTCATCATTACGACTGGT
    GGAACAGGTATTGCACAACGTGATGTGACGATTGAAGCAGTAAAACCACTTTTAACTAAA
    GAGATAGATGGCTTTGGGGAATTGTTTAGATATTTGAGTTATGTTGAAGATGTTGGCACG
    CGTGCATTATTGTCTCGTGCTGTAGCAGGTACAGTTAATAATAAATTGATATTTTCGATT
    CCAGGATCAACAGGCGCAGTTAAATTAGCATTAGAAAAGCTCATTAAACCAGAATTAAAT
    CATCTGATTCATGAGCTTACAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    507

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_2226 [new locus tag: SAUSA300_RS12295 ]
  • symbol: MoaB
  • description: molybdenum cofactor biosynthesis protein B
  • length: 168
  • theoretical pI: 5.67966
  • theoretical MW: 18486
  • GRAVY: -0.119643

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Molybdopterin molybdenum cofactor biosynthesis protein B (TIGR02667; HMM-score: 159.4)
    and 2 more
    molybdenum cofactor synthesis domain (TIGR00177; HMM-score: 121.5)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair competence/damage-inducible protein CinA N-terminal domain (TIGR00200; HMM-score: 11.1)
  • TheSEED  :
    • Molybdenum cofactor biosynthesis protein MoaB
    Cofactors, Vitamins, Prosthetic Groups, Pigments Folate and pterines Molybdenum cofactor biosynthesis  Molybdenum cofactor biosynthesis protein MoaB
  • PFAM:
    no clan defined MoCF_biosynth; Probable molybdopterin binding domain (PF00994; HMM-score: 109.9)
    and 2 more
    AA_dh_N (CL0603) malic; Malic enzyme, N-terminal domain (PF00390; HMM-score: 12.6)
    TIM_barrel (CL0036) DHDPS; Dihydrodipicolinate synthetase family (PF00701; HMM-score: 11.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008014
    • TAT(Tat/SPI): 0.000619
    • LIPO(Sec/SPII): 0.001577
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIDGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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