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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_1844 [new locus tag: SAUSA300_RS10070 ]
  • pan locus tag?: SAUPAN004843000
  • symbol: SAUSA300_1844
  • pan gene symbol?: bcp
  • synonym:
  • product: bacterioferritin comigratory protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_1844 [new locus tag: SAUSA300_RS10070 ]
  • symbol: SAUSA300_1844
  • product: bacterioferritin comigratory protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2004963..2005418
  • length: 456
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGTTGCAAAAAGGAGAACAATTTCCAATATTTAAATTAGAAAATCAAGACGGAACTGTC
    ATTACAAATGATACATTAAAAGGTAAAAAGGCGATTATATATTTTTATCCTAGAGATAAT
    ACACCTACTTGTACCACAGAAGCTTGTGACTTTAGAGACAATTTAGAAATGTTCAATGAT
    TTAGATGTTGCAGTATATGGTATAAGCGGTGATTCAAAGAAAAAACACCAAAATTTTATT
    GAGAAACACGGATTGAATTTCGATTTATTAGTAGATGAAGATTTTAAATTAGCTAAAGAA
    ACTGGCGTATATCAGTTAAAAAAATCATTTGGCAAAGAAAGTATGGGCATTGTAAGAACG
    ACTTTTATAATAGATGAACAAGGTAAAGTATTAGATGTTATCGAGAAGGTTAAGGTTAAA
    ACACAAATAGAAGAACTTAAAAACATTTTGGGGTGA
    60
    120
    180
    240
    300
    360
    420
    456

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_1844 [new locus tag: SAUSA300_RS10070 ]
  • symbol: SAUSA300_1844
  • description: bacterioferritin comigratory protein
  • length: 151
  • theoretical pI: 5.33808
  • theoretical MW: 17259.7
  • GRAVY: -0.450331

⊟Function[edit | edit source]

  • reaction:
    EC 1.11.1.-?  ExPASy
  • TIGRFAM:
    Cellular processes Cellular processes Detoxification peroxiredoxin (TIGR03137; EC 1.11.1.15; HMM-score: 60.6)
    Cellular processes Cellular processes Adaptations to atypical conditions peroxiredoxin (TIGR03137; EC 1.11.1.15; HMM-score: 60.6)
  • TheSEED  :
    • Thiol peroxidase, Bcp-type (EC 1.11.1.24)
    Sulfur Metabolism Sulfur Metabolism - no subcategory Thioredoxin-disulfide reductase  Thiol peroxidase, Bcp-type (EC 1.11.1.15)
  • PFAM:
    Thioredoxin (CL0172) AhpC-TSA; AhpC/TSA family (PF00578; HMM-score: 122.2)
    and 3 more
    Redoxin; Redoxin (PF08534; HMM-score: 80.6)
    AhpC-TSA_2; AhpC/TSA antioxidant enzyme (PF13911; HMM-score: 20)
    SCO1-SenC; SCO1/SenC (PF02630; HMM-score: 19.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.11
    • Cytoplasmic Membrane Score: 0.93
    • Cellwall Score: 8.19
    • Extracellular Score: 0.77
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.050865
    • TAT(Tat/SPI): 0.001169
    • LIPO(Sec/SPII): 0.003208
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MLQKGEQFPIFKLENQDGTVITNDTLKGKKAIIYFYPRDNTPTCTTEACDFRDNLEMFNDLDVAVYGISGDSKKKHQNFIEKHGLNFDLLVDEDFKLAKETGVYQLKKSFGKESMGIVRTTFIIDEQGKVLDVIEKVKVKTQIEELKNILG

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: PerR* (repression) regulon
    PerR*(TF)important in Oxidative stress response; RegPrecise 

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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