PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 10-JUN-2013

⊟Summary

• organism: Staphylococcus aureus USA300_FPR3757
• locus tag: SAUSA300_0896 [new locus tag: SAUSA300_RS04830 ]
• pan locus tag^?: SAUPAN003156000
• symbol: oppC
• pan gene symbol^?: opp4C
• synonym:
• product: oligopeptide ABC transporter permease

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SAUSA300_0896 [new locus tag: SAUSA300_RS04830 ]
• symbol: oppC
• product: oligopeptide ABC transporter permease
• replicon: chromosome
• strand: +
• coordinates: 984763..985644
• length: 882
• essential: unknown other strains

⊟Accession numbers

• Gene ID: 3914976 NCBI
• RefSeq: YP_493596 NCBI
• BioCyc: see SAUSA300_RS04830
• MicrobesOnline: 1292411 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  
  ATGCAAAATAAGTCAAAATCGCCTTTTAAAATTGCATTTTCTAAATTTATTCATAATAAA
  ATTGCAATGTTATCGGTTATTTTTTTATTAATCATAACTATTGTATCAATTATAGCGCCA
  TTAATAGCTCCTTTTCCAGTGAACCAACAAGATTTATTAAATATAAAAGGTGAAATGACA
  GCACAAAACATTCTTGGTACAGACTCTGGTGGTAGGGATAACTTTAGTCGTTTGTTATAT
  GCAGGTCGTATTTCATTATCCATTGGAATTACATCTACAATAGGAATGCTTTTGATTGGA
  ATTACAGTTGGAGTGATTTCTGGTTATTTTGGAGGTATTGTTGATACATTATTAATGAGA
  ATAACCGAATTTGTTATGTTATTTCCATTTTTAATATTTGCAATTGTATTAAATGCTGCA
  CTTGGAGATAAAATTAAAAATCCTTATGGATCTGCCATAATTCTTGTTCTAGTTATTATC
  GTATTAAGTTGGGGAGGTATTGCAAGACTTGTTCGTGGTAAAGTACTTCAAGAAAAAGAA
  AATGAATACTTTTTGGCAGCAAAATCAATTGGTACACCCACATATAAAATTATTTTGAAA
  CATCTTTTGCCGAATATATTAAGTGTAGTTATCGTACAAGCAACATTGTTATTTGCCGGT
  ATGATTGTAGTGGAATCAGGATTGAGCTTTTTAGGATTCGGAATTAGTAAAGCAATACCA
  TCTTGGGGTAATATGTTGAGTGATGCTCAAGAAGGGGATGTTATAAGTGGTAAACCGTGG
  ATATGGATGCCACCTGCTATAATGATTACATTAACTATATTAAGTATAAACTTTGTAGGG
  GAAGGGATTAAAGATGCTTTTAATCCTAGAGGTAGACGTTAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  882
  

⊟Protein

⊟General

• locus tag: SAUSA300_0896 [new locus tag: SAUSA300_RS04830 ]
• symbol: OppC
• description: oligopeptide ABC transporter permease
• length: 293
• theoretical pI: 10.4056
• theoretical MW: 31819.9
• GRAVY: 0.722526

⊟Function

• TIGRFAM:
  Metabolism Transport and binding proteins Cations and iron carrying compounds nickel ABC transporter, permease subunit NikC (TIGR02790; EC 3.6.3.24; HMM-score: 202.1)
  and 3 more
  Metabolism Transport and binding proteins Cations and iron carrying compounds nickel ABC transporter, permease subunit NikB (TIGR02789; EC 3.6.3.24; HMM-score: 22.3)
  Metabolism Transport and binding proteins Anions sulfate ABC transporter, permease protein CysT (TIGR02139; HMM-score: 19)
  Metabolism Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, permease protein (TIGR03262; HMM-score: 14.5)
• TheSEED  :
  • Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1)
  Membrane Transport ABC transporters ABC transporter oligopeptide (TC 3.A.1.5.1)  Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1)
• PFAM:
  BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 107.7)
  and 1 more
  no clan defined OppC_N; N-terminal TM domain of oligopeptide transport permease C (PF12911; HMM-score: 41.8)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 6
• LocateP: Multi-transmembrane
  • Prediction by SwissProt Classification: Membrane
  • Pathway Prediction: Sec-(SPI)
  • Intracellular possibility: 0.17
  • Signal peptide possibility: 0
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.184731
  • TAT(Tat/SPI): 0.00093
  • LIPO(Sec/SPII): 0.004192
• predicted transmembrane helices (TMHMM): 6

⊟Accession numbers

• GI: 87159930 NCBI
• RefSeq: YP_493596 NCBI
• UniProt: A0A0H2XDX4 UniProt

⊟Protein sequence

• MQNKSKSPFKIAFSKFIHNKIAMLSVIFLLIITIVSIIAPLIAPFPVNQQDLLNIKGEMTAQNILGTDSGGRDNFSRLLYAGRISLSIGITSTIGMLLIGITVGVISGYFGGIVDTLLMRITEFVMLFPFLIFAIVLNAALGDKIKNPYGSAIILVLVIIVLSWGGIARLVRGKVLQEKENEYFLAAKSIGTPTYKIILKHLLPNILSVVIVQATLLFAGMIVVESGLSFLGFGISKAIPSWGNMLSDAQEGDVISGKPWIWMPPAIMITLTILSINFVGEGIKDAFNPRGRR

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: oppA > oppF > oppD > oppB > oppC

⊟Regulation

• regulator: CodY (repression) regulon

  CodY

  (TF)

  important in Amino acid metabolism; RegPrecise    transcription unit transferred from N315 data RegPrecise

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications