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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_0347 [new locus tag: SAUSA300_RS01840 ]
  • pan locus tag?: SAUPAN001888000
  • symbol: tatC
  • pan gene symbol?: tatC
  • synonym:
  • product: Sec-independent protein translocase TatC

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_0347 [new locus tag: SAUSA300_RS01840 ]
  • symbol: tatC
  • product: Sec-independent protein translocase TatC
  • replicon: chromosome
  • strand: -
  • coordinates: 399889..400545
  • length: 657
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    TTGTCGTTCGTCATTACGGTCATCGTCGTATATGTTTCATCATTTTGGTGGATGACACCA
    TTCATAACGTATATTACCCGTGCACATGTGTCCTTACATGCATTTTCATTCACAGAAATG
    ATACAAATATACGTGATGATTATATTTTTCATCGCGTTTTGTTTCATTTCACCAGTCATG
    TTTTATCAATTGTGGGCATTCATTGCACCTGGATTACATAATAATGAACGTCAATTTATT
    TATAAATATAGTTTTTTCAGCGTGTTATTATTCTGTGCTGGCGTCGCTTTTGCATTTTAT
    GTTGGCTTTCCAATGATCATTCAATTCGCGTTAAAATTATCATTAACTTTAAACATTTCG
    CCTGTCATTGGCTTTAAAGCATATTTGATTGAACTCATACGTTGGTTATTCACATTTGGT
    CTTCTATTTCAATTACCAATATTATTTATGGGTCTTGCAAAATTCGGTCTTATAGATACC
    ACATCATTGAAACATTATCGTAAATATATTTATTTCGCTTGCTTTGTATTAGCAAGTATC
    ATTGCACCACCCGATTTAACATTAAATATATTACTCACATTGCCACTCATATTGCTCTTT
    GAGTTCAGTATGTTCATCGTTAAGTTCACATGCCGAGGCAAACCGCCAACACATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    657

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_0347 [new locus tag: SAUSA300_RS01840 ]
  • symbol: TatC
  • description: Sec-independent protein translocase TatC
  • length: 218
  • theoretical pI: 9.48042
  • theoretical MW: 25382.6
  • GRAVY: 1.09633

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking twin arginine-targeting protein translocase TatC (TIGR00945; HMM-score: 148.9)
    Sec-independent protein translocase TatC (TIGR01912; HMM-score: 120)
  • TheSEED  :
    • Twin-arginine translocation protein TatC
    Membrane Transport Protein translocation across cytoplasmic membrane Twin-arginine translocation system  Twin-arginine translocation protein TatC
  • PFAM:
    no clan defined TatC; Sec-independent protein translocase protein (TatC) (PF00902; HMM-score: 138)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 7
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004316
    • TAT(Tat/SPI): 0.000272
    • LIPO(Sec/SPII): 0.043409
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSFVITVIVVYVSSFWWMTPFITYITRAHVSLHAFSFTEMIQIYVMIIFFIAFCFISPVMFYQLWAFIAPGLHNNERQFIYKYSFFSVLLFCAGVAFAFYVGFPMIIQFALKLSLTLNISPVIGFKAYLIELIRWLFTFGLLFQLPILFMGLAKFGLIDTTSLKHYRKYIYFACFVLASIIAPPDLTLNILLTLPLILLFEFSMFIVKFTCRGKPPTH

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: Fur* (repression) regulon
    Fur*(TF)important in Iron homeostasis; RegPrecise    transcription unit transferred from N315 data RegPrecise 

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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