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⊟Summary[edit | edit source]
- pan ID?: SAUPAN006363000
- symbol?: arcB
- synonym:
- description?: ornithine carbamoyltransferase
- ornithine carbamoyltransferase
- Ornithine carbamoyltransferase, catabolic
- catabolic ornithine carbamoyltransferase
- putative ornithine carbamoyltransferase
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 6397911..6398921
- synteny block?: BlockID0050720
- occurrence?: in 100% of 34 strains
arcBc (arcBCONS) : constitutive arginine catabolism ornithine carbamoyltransferase [1]
• this version of ArcB is part of the core staphylococcal genome and is found in all strains. It is part of the arginine deiminase pathway that is actively transcribed only during aerobic growth. The "c" after "arcB" is to differentiate this version from the "a" version found in the Arginine Catabolic Metabolic Element (ACME) that sometimes accompanies the SCCmec element in MRSA, particularly the USA300 clade.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_2573 (arcB)
08BA02176:
C248_2702 (arcB)
11819-97:
MS7_2639
6850:
RSAU_002477 (arcB2)
71193:
ST398NM01_2684
ECT-R 2:
ECTR2_2488 (argF)
ED133:
SAOV_2683c
ED98:
SAAV_2703 (arcB2)
HO 5096 0412:
SAEMRSA15_25390 (arcB)
JH1:
SaurJH1_2714
JH9:
SaurJH9_2658
JKD6008:
SAA6008_02693 (arcB)
JKD6159:
SAA6159_02530 (arcB)
JSNZ:
JSNZ_002623 (argF)
LGA251:
SARLGA251_24060 (arcB)
M013:
M013TW_2615
MRSA252:
SAR2713 (arcB)
MSHR1132:
SAMSHR1132_24580
MSSA476:
SAS2520
Mu3:
SAHV_2618 (arcB)
Mu50:
SAV2634 (arcB)
MW2:
MW2555 (arcB)
RF122:
SAB2509c (arcB)
ST398:
SAPIG2684 (argF)
T0131:
SAT0131_02900 (alr2)
TCH60:
HMPREF0772_10554 (argF)
TW20:
SATW20_27720 (arcB)
USA300_TCH1516:
USA300HOU_2634 (arcB3)
VC40:
SAVC_12050
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MTEIQKPYDLKGRSLLKESDFTKAEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEK
N315 MTEIQKPYDLKGRSLLKESDFTKAEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEK
NCTC8325 MTEIQKPYDLKGRSLLKESDFTKAEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEK
Newman MTEIQKPYDLKGRSLLKESDFTKAEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEK
USA300_FPR3757 MTEIQKPYDLKGRSLLKESDFTKAEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEK
************************************************************
COL NSTRTRAAFTVASIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAV
N315 NSTRTRAAFTVASIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAV
NCTC8325 NSTRTRAAFTVASIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAV
Newman NSTRTRAAFTVASIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAV
USA300_FPR3757 NSTRTRAAFTVASIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAV
************************************************************
COL EDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEGINLTYVGDGRNNIAHSLMVA
N315 EDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEGINLTYVGDGRNNIAHSLMVA
NCTC8325 EDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEGINLTYVGDGRNNIAHSLMVA
Newman EDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEGINLTYVGDGRNNIAHSLMVA
USA300_FPR3757 EDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEGINLTYVGDGRNNIAHSLMVA
************************************************************
COL GAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVS
N315 GAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSIMITDNIAEAVENTDAIYTDVWVS
NCTC8325 GAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVS
Newman GAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVS
USA300_FPR3757 GAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVS
************************************:***********************
COL MGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAE
N315 MGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAE
NCTC8325 MGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAE
Newman MGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAE
USA300_FPR3757 MGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAE
************************************************************
COL MEVTDQIFRSEHSKVFDQAENRMHTIKAVMAATLGS
N315 MEVTDQIFRSEHSKVFDQAENRMHTIKAVMAATLGS
NCTC8325 MEVTDQIFRSEHSKVFDQAENRMHTIKAVMAATLGS
Newman MEVTDQIFRSEHSKVFDQAENRMHTIKAVMAATLGS
USA300_FPR3757 MEVTDQIFRSEHSKVFDQAENRMHTIKAVMAATLGS
************************************
- ↑ Julia Makhlin, Tzili Kofman, Ilya Borovok, Christian Kohler, Susanne Engelmann, Gerald Cohen, Yair Aharonowitz
Staphylococcus aureus ArcR controls expression of the arginine deiminase operon.
J Bacteriol: 2007, 189(16);5976-86
[PubMed:17557828] [WorldCat.org] [DOI] (P p)Zayda Lorena Corredor Rozo, Ricaurte Alejandro Márquez-Ortiz, Betsy Esperanza Castro, Natasha Vanegas Gómez, Javier Escobar-Pérez
Participation of the arcRACME protein in self-activation of the arc operon located in the arginine catabolism mobile element in pandemic clone USA300.
Mem Inst Oswaldo Cruz: 2017, 112(7);499-503
[PubMed:28591311] [WorldCat.org] [DOI] (I p)