Jump to navigation
Jump to search
⊟Summary[edit | edit source]
- pan ID?: SAUPAN006362000
- symbol?: arcD
- synonym:
- description?: arginine-ornithine antiporter
- arginine-ornithine antiporter
- arginine/ornithine antiporter
- arginine/oirnithine antiporter
- arginine/oirnithine antiporter ArcD
- APC family amino acid-polyamine-organocation transporter
- APC family arginine/ornithine antiporter
- Arginine/ornithine antiporter ArcD
- arginine/ornithine APC family amino acid-polyamine-organocation transporter, antiporter
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 6396384..6397814
- synteny block?: BlockID0050710
- occurrence?: in 100% of 34 strains
arcDc (arcDCONS) : constitutive arginine catabolism arginine/ornithine antiporter [1]
• this version of ArcD is part of the core staphylococcal genome and is found in all strains. It is part of the arginine deiminase pathway that is actively transcribed only during aerobic growth. The "c" after "arcD" is to differentiate this version from the "a" version found in the Arginine Catabolic Metabolic Element (ACME) that sometimes accompanies the SCCmec element in MRSA, particularly the USA300 clade.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_2572 (arcD)
08BA02176:
C248_2701 (arcD)
11819-97:
MS7_2638 (arcD)
6850:
RSAU_002476 (arcD)
71193:
ST398NM01_2683
ECT-R 2:
ECTR2_2487
ED133:
SAOV_2682c
ED98:
SAAV_2702 (arcD)
HO 5096 0412:
SAEMRSA15_25380 (arcD)
JH1:
SaurJH1_2713
JH9:
SaurJH9_2657
JKD6008:
SAA6008_02692 (arcD)
JKD6159:
SAA6159_02529 (arcD)
JSNZ:
JSNZ_002622 (arcD)
LGA251:
SARLGA251_24050 (arcD)
M013:
M013TW_2614
MRSA252:
SAR2712 (arcD)
MSHR1132:
SAMSHR1132_24570
MSSA476:
SAS2519
Mu3:
SAHV_2617 (arcD)
Mu50:
SAV2633 (arcD)
MW2:
MW2554 (arcD)
RF122:
SAB2508c (arcD)
ST398:
SAPIG2683
T0131:
SAT0131_02899 (hipO)
TCH60:
HMPREF0772_10555 (arcD)
TW20:
SATW20_27710 (arcD)
USA300_TCH1516:
USA300HOU_2633 (arcD3)
VC40:
SAVC_12045
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MNESGDNKLSKSSLIGLVIGSMIGGGAFNIMSDMGGKAGGLAIIIGWIITAIGMISLAFV
N315 MNESGDNKLSKSSLIGLVIGSMIGGGAFNIMSDMGGKAGGLAIIIGWIITAIGMISLAFV
NCTC8325 MNESGDNKLSKSSLIGLVIGSMIGGGAFNIMSDMGGKAGGLAIIIGWIITAIGMISLAFV
Newman MNESGDNKLSKSSLIGLVIGSMIGGGAFNIMSDMGGKAGGLAIIIGWIITAIGMISLAFV
USA300_FPR3757 MNESGDNKLSKSSLIGLVIGSMIGGGAFNIMSDMGGKAGGLAIIIGWIITAIGMISLAFV
************************************************************
COL FQNLTNERPELDGGIYSYAQAGFGDFVGFISAWGYWFSAFLGNVAYATLLMSAVGNFFPI
N315 FQNLTNERPELDGGIYSYAQAGFGDFVGFISAWGYWFSAFLGNVAYATLLMSAVGNFFPI
NCTC8325 FQNLTNERPELDGGIYSYAQAGFGDFVGFISAWGYWFSAFLGNVAYATLLMSAVGNFFPI
Newman FQNLTNERPELDGGIYSYAQAGFGDFVGFISAWGYWFSAFLGNVAYATLLMSAVGNFFPI
USA300_FPR3757 FQNLTNERPELDGGIYSYAQAGFGDFVGFISAWGYWFSAFLGNVAYATLLMSAVGNFFPI
************************************************************
COL FKGGNTLPSVIVASLLLWGVHFLILKGVETAAFINSIVTVAKLIPILLVIICMIIAFNFD
N315 FKGGNTLPSIIVASLLLWGVHFLILKGVETAAFINSIVTVAKLIPILLVIICMIIAFNFD
NCTC8325 FKGGNTLPSVIVASLLLWGVHFLILKGVETAAFINSIVTVAKLIPILLVIICMIIAFNFD
Newman FKGGNTLPSVIVASLLLWGVHFLILKGVETAAFINSIVTVAKLIPILLVIICMIIAFNFD
USA300_FPR3757 FKGGNTLPSVIVASLLLWGVHFLILKGVETAAFINSIVTVAKLIPILLVIICMIIAFNFD
*********:**************************************************
COL TFKTGFFSMTSEGVLPFSWASTMSQVKSTMLVTVWVFIGIEGAVIFSSRAKNKKDVGSAT
N315 TFKTGFFGMTSEGVLPFSWASTMSQVKSTMLVTVWVFIGIEGAVIFSSRAKNKKDVGSAT
NCTC8325 TFKTGFFSMTSEGVLPFSWASTMSQVKSTMLVTVWVFIGIEGAVIFSSRAKNKKDVGSAT
Newman TFKTGFFSMTSEGVLPFSWASTMSQVKSTMLVTVWVFIGIEGAVIFSSRAKNKKDVGSAT
USA300_FPR3757 TFKTGFFSMTSEGVLPFSWASTMSQVKSTMLVTVWVFIGIEGAVIFSSRAKNKKDVGSAT
*******.****************************************************
COL VIGLISVLIIYFLLTVLAQGVILQNHISQLDSPSMAQVLATIVGGWGSTLVNIGLIISVL
N315 VIGLISVLIIYFLLTVLAQGVILQNHISQLDSPSMAQVLATIVGGWGSTLVNIGLIISVL
NCTC8325 VIGLISVLIIYFLLTVLAQGVILQNHISQLDSPSMAQVLATIVGGWGSTLVNIGLIISVL
Newman VIGLISVLIIYFLLTVLAQGVILQNHISQLDSPSMAQVLATIVGGWGSTLVNIGLIISVL
USA300_FPR3757 VIGLISVLIIYFLLTVLAQGVILQNHISQLDSPSMAQVLATIVGGWGSTLVNIGLIISVL
************************************************************
COL GAWLGWTLLAGELPFIVAKDGLFPKWFAKENKNGAPVNALLITNILVQLFLISMLFTQSA
N315 GAWLGWTLLAGELPFIVAKDGLFPKWFAKENKNGAPVNALLITNILVQLFLISMLFTQSA
NCTC8325 GAWLGWTLLAGELPFIVAKDGLFPKWFAKENKNGAPVNALLITNILVQLFLISMLFTQSA
Newman GAWLGWTLLAGELPFIVAKDGLFPKWFAKENKNGAPVNALLITNILVQLFLISMLFTQSA
USA300_FPR3757 GAWLGWTLLAGELPFIVAKDGLFPKWFAKENKNGAPVNALLITNILVQLFLISMLFTQSA
************************************************************
COL YQFAFSLASSAILYPYMFSAFYQVKYTLEHRQQATTKQWTIGIIASIYAIWLIYAAGINY
N315 YQFAFSLASSAILYPYMFSAFYQVKYTLEHRQQATTKQWTIGIIASIYAIWLIYAAGINY
NCTC8325 YQFAFSLASSAILYPYMFSAFYQVKYTLEHRQQATTKQWTIGIIASIYAIWLIYAAGINY
Newman YQFAFSLASSAILYPYMFSAFYQVKYTLEHRQQATTKQWTIGIIASIYAIWLIYAAGINY
USA300_FPR3757 YQFAFSLASSAILYPYMFSAFYQVKYTLEHRQQATTKQWTIGIIASIYAIWLIYAAGINY
************************************************************
COL LLLTMLLYIPALLVYTIVQKNNQTRLIKSDYILFMIIIVLAVIGLIKLLMGTINVF
N315 LLLTMLLYIPALLVYSIVQKNNQTRLIKSDYILFMIIIVLAVIGLIKLLMGTINVF
NCTC8325 LLLTMLLYIPALLVYTIVQKNNQTRLIKSDYILFMIIIVLAVIGLIKLLMGTINVF
Newman LLLTMLLYIPALLVYTIVQKNNQTRLIKSDYILFMIIIVLAVIGLIKLLMGTINVF
USA300_FPR3757 LLLTMLLYIPALLVYTIVQKNNQTRLIKSDYILFMIIIVLAVIGLIKLLMGTINVF
***************:****************************************
- ↑ Julia Makhlin, Tzili Kofman, Ilya Borovok, Christian Kohler, Susanne Engelmann, Gerald Cohen, Yair Aharonowitz
Staphylococcus aureus ArcR controls expression of the arginine deiminase operon.
J Bacteriol: 2007, 189(16);5976-86
[PubMed:17557828] [WorldCat.org] [DOI] (P p)Zayda Lorena Corredor Rozo, Ricaurte Alejandro Márquez-Ortiz, Betsy Esperanza Castro, Natasha Vanegas Gómez, Javier Escobar-Pérez
Participation of the arcRACME protein in self-activation of the arc operon located in the arginine catabolism mobile element in pandemic clone USA300.
Mem Inst Oswaldo Cruz: 2017, 112(7);499-503
[PubMed:28591311] [WorldCat.org] [DOI] (I p)