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Summary[edit | edit source]

  • pan ID?: SAUPAN006206000
  • symbol?: mvaA
  • synonym:
  • description?: hydroxymethylglutaryl-CoA reductase, degradative

      descriptions from strain specific annotations:

    • hydroxymethylglutaryl-CoA reductase, degradative
    • hydroxymethylglutaryl-CoA reductase
    • 3-hydroxy-3-methylglutaryl-CoA reductase
    • 3-hydroxy-3-methylglutaryl-coenzyme A reductase
  • strand?: -
  • coordinates?: 6265418..6266698
  • synteny block?: BlockID0049300
  • occurrence?: in 100% of 33 strains

Orthologs[edit | edit source]

    COL:
    N315:
    SA2333 (mvaA)
    NCTC8325:
    Newman:
    NWMN_2445 (mvaA)
    USA300_FPR3757:
    04-02981:
    SA2981_2481 (mvaA)
    08BA02176:
    C248_2602 (mvaA)
    11819-97:
    MS7_2550
    6850:
    RSAU_002385 (mvaA)
    71193:
    ST398NM01_2595
    ECT-R 2:
    ECTR2_2397
    ED133:
    SAOV_2589c
    ED98:
    SAAV_2611
    HO 5096 0412:
    SAEMRSA15_24480 (mvaA)
    JH1:
    SaurJH1_2621
    JH9:
    SaurJH9_2568
    JKD6008:
    SAA6008_02583 (mvaA)
    JKD6159:
    SAA6159_02441 (mvaA)
    LGA251:
    SARLGA251_23200 (mvaA)
    M013:
    M013TW_2517
    MRSA252:
    SAR2625 (mvaA)
    MSHR1132:
    SAMSHR1132_23650
    MSSA476:
    SAS2431
    Mu3:
    SAHV_2529 (mvaA)
    Mu50:
    SAV2545 (mvaA)
    MW2:
    MW2466 (mvaA)
    RF122:
    SAB2419c (mvaA)
    ST398:
    SAPIG2595
    T0131:
    SAT0131_02754
    TCH60:
    HMPREF0772_10646 (mvaA)
    TW20:
    SATW20_26670 (mvaA)
    USA300_TCH1516:
    USA300HOU_2539
    VC40:
    SAVC_11605

Genome Viewer[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757

Alignments[edit | edit source]

  • alignment of orthologues:
    CLUSTAL format alignment by MAFFT L-INS-i (v7.307)


    COL             MQNLDKNFRHLSRKEKLQQLVDKQWLSEEQFDILLNHPLIDEEVANSLIENVIAQGALPV
    N315            MQSLDKNFRHLSRQQKLQQLVDKQWLSEDQFDILLNHPLIDEEVANSLIENVIAQGALPV
    NCTC8325        MQNLDKNFRHLSRKEKLQQLVDKQWLSEEQFDILLNHPLIDEEVANSLIENVIAQGALPV
    Newman          MQNLDKNFRHLSRKEKLQQLVDKQWLSEEQFDILLNHPLIDEEVANSLIENVIAQGALPV
    USA300_FPR3757  MQNLDKNFRHLSRKEKLQQLVDKQWLSEEQFDILLNHPLIDEEVANSLIENVIAQGALPV
                    **.**********::*************:*******************************

    COL             GLLPNIIVDDKAYVVPMMVEEPSVVAAASYGAKLVNQTGGFKTVSSERIMIGQIVFDGVD
    N315            GLLPNIIVDDKAYVVPMMVEEPSVVAAASYGAKLVNQTGGFKTVSSERIMIGQIVFDGVD
    NCTC8325        GLLPNIIVDDKAYVVPMMVEEPSVVAAASYGAKLVNQTGGFKTVSSERIMIGQIVFDGVD
    Newman          GLLPNIIVDDKAYVVPMMVEEPSVVAAASYGAKLVNQTGGFKTVSSERIMIGQIVFDGVD
    USA300_FPR3757  GLLPNIIVDDKAYVVPMMVEEPSVVAAASYGAKLVNQTGGFKTVSSERIMIGQIVFDGVD
                    ************************************************************

    COL             DTEKLSADIKALEKQIHKIADEAYPSIKARGGGYQRIAIDTFPEQQLLSLKVFVDTKDAM
    N315            DTEKLSADIKALEKQIHKIADEAYPSIKARGGGYQRIAIDTFPEQQLLSLKVFVDTKDAM
    NCTC8325        DTEKLSADIKALEKQIHKIADEAYPSIKARGGGYQRIAIDTFPEQQLLSLKVFVDTKDAM
    Newman          DTEKLSADIKALEKQIHKIADEAYPSIKARGGGYQRIAIDTFPEQQLLSLKVFVDTKDAM
    USA300_FPR3757  DTEKLSADIKALEKQIHKIADEAYPSIKARGGGYQRIAIDTFPEQQLLSLKVFVDTKDAM
                    ************************************************************

    COL             GANMLNTILEAITAFLKNEFPQSDILMSILSNHATASVVKVQGEIDVKDLARGERTGEEV
    N315            GANMLNTILEAITAFLKNESPQSDILMSILSNHATASVVKVQGEIDVKDLARGERTGEEV
    NCTC8325        GANMLNTILEAITAFLKNEFPQSDILMSILSNHATASVVKVQGEIDVKDLARGERTGEEV
    Newman          GANMLNTILEAITAFLKNEFPQSDILMSILSNHATASVVKVQGEIDVKDLARGERTGEEV
    USA300_FPR3757  GANMLNTILEAITAFLKNEFPQSDILMSILSNHATASVVKVQGEIDVKDLARGERTGEEV
                    ******************* ****************************************

    COL             AKRMERASVLAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASRDGQYRGI
    N315            AKRMERASVLAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASRDGQYRGI
    NCTC8325        AKRMERASVLAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASRDGQYRGI
    Newman          AKRMERASVLAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASRDGQYRGI
    USA300_FPR3757  AKRMERASVLAQVDIHRAATHNKGVMNGIHAVVLATGNDTRGAEASAHAYASRDGQYRGI
                    ************************************************************

    COL             ATWRYDQDRQRLIGTIEVPMTLAIVGGGTKVLPIAKASLELLNVESAQELGHVVAAVGLA
    N315            ATWRYDQKRQRLIGTIEVPMTLAIVGGGTKVLPIAKASLELLNVDSAQELGHVVAAVGLA
    NCTC8325        ATWRYDQDRQRLIGTIEVPMTLAIVGGGTKVLPIAKASLELLNVESAQELGHVVAAVGLA
    Newman          ATWRYDQDRQRLIGTIEVPMTLAIVGGGTKVLPIAKASLELLNVESAQELGHVVAAVGLA
    USA300_FPR3757  ATWRYDQDRQRLIGTIEVPMTLAIVGGGTKVLPIAKASLELLNVESAQELGHVVAAVGLA
                    *******.************************************:***************

    COL             QNFAACRALVSEGIQQGHMSLQYKSLAIVVGAKGDEIAKVAEALKKEPRANTQAAEHILQ
    N315            QNFAACRALVSEGIQQGHMSLQYKSLAIVVGAKGDEIAQVAEALKQEPRANTQVAERILQ
    NCTC8325        QNFAACRALVSEGIQQGHMSLQYKSLAIVVGAKGDEIAKVAEALKKEPRANTQAAEHILQ
    Newman          QNFAACRALVSEGIQQGHMSLQYKSLAIVVGAKGDEIAKVAEALKKEPRANTQAAEHILQ
    USA300_FPR3757  QNFAACRALVSEGIQQGHMSLQYKSLAIVVGAKGDEIAKVAEALKKEPRANTQAAEHILQ
                    **************************************:******:*******.**:***

    COL             EIRQQ
    N315            EIRQQ
    NCTC8325        EIRQQ
    Newman          EIRQQ
    USA300_FPR3757  EIRQQ
                    *****