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⊟Summary[edit | edit source]
- pan ID?: SAUPAN005924000
- symbol?: nreA
- synonym:
- description?: GAF domain-containing protein
- GAF domain-containing protein
- control of nitrate reduction, putative
- nitrate respiration regulation accessory nitrate sensor NreA
- NreA
- nreA protein
- transcriptional regulator
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 5988622..5989074
- synteny block?: BlockID0046680
- occurrence?: in 97% of 34 strains
nreA : nitrate-sensing NreB inhibitor NreA [1]
• A crystal structure is available : 4PAU
⊟Orthologs[edit | edit source]
04-02981:
SA2981_2330
08BA02176:
C248_2440
11819-97:
MS7_2408 (nreA)
6850:
RSAU_002231
71193:
ST398NM01_2446
ECT-R 2:
ECTR2_2252
ED133:
—
ED98:
SAAV_2458
HO 5096 0412:
SAEMRSA15_22920
JH1:
SaurJH1_2465
JH9:
SaurJH9_2417
JKD6008:
SAA6008_02434
JKD6159:
SAA6159_02294
JSNZ:
JSNZ_002361 (nreA)
LGA251:
SARLGA251_21750 (nreA)
M013:
M013TW_2354
MRSA252:
SAR2482
MSHR1132:
SAMSHR1132_22210
MSSA476:
SAS2284
Mu3:
SAHV_2377
Mu50:
SAV2393
MW2:
MW2315
RF122:
SAB2272c
ST398:
SAPIG2446
T0131:
SAT0131_02584 (lspA)
TCH60:
HMPREF0772_10794
TW20:
SATW20_25230 (nreA)
USA300_TCH1516:
USA300HOU_2375
VC40:
SAVC_10835
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MTPEAIIEDRRFQETLDKIRKEEGYDFAAIAFYESNKPSSPIKWHYVSGNKNNRFKLIIL
N315 MTPEAIIEDRRFQETLDKIRKEEGYDFAAIAFYESNKPSSPIKWHYVSGNKNNRFKLIIL
NCTC8325 MTPEAIIEDRRFQETLDKIRKEEGYDFAAIAFYESNKPSSPIKWHYVSGNKNNRFKLIIL
Newman MTPEAIIEDRRFQETLDKIRKEEGYDFAAIAFYESNKPSSPIKWHYVSGNKNNRFKLIIL
USA300_FPR3757 MTPEAIIEDRRFQETLDKIRKEEGYDFAAIAFYESNKPSSPIKWHYVSGNKNNRFKLIIL
************************************************************
COL RKGRGLAGTVMKTGKRMVIANVGLALGPEEKIDYPILLSESLTAVLAVPLWYKNQVYGVL
N315 RKGRGLAGTVMKTGKRMVIANVGLALGPEEKIDYPILLSESLTAVLAVPLWYKNQVYGVL
NCTC8325 RKGRGLAGTVMKTGKRMVIANVGLALGPEEKIDYPILLSESLTAVLAVPLWYKNQVYGVL
Newman RKGRGLAGTVMKTGKRMVIANVGLALGPEEKIDYPILLSESLTAVLAVPLWYKNQVYGVL
USA300_FPR3757 RKGRGLAGTVMKTGKRMVIANVGLALGPEEKIDYPILLSESLTAVLAVPLWYKNQVYGVL
************************************************************
COL LFGQRDGRPLPKIFDNDDIQRKFGIFNDDK
N315 LFGQRDGRPLPKIFDNDDIQRKFGIFNDDK
NCTC8325 LFGQRDGRPLPKIFDNDDIQRKFGIFNDDK
Newman LFGQRDGRPLPKIFDNDDIQRKFGIFNDDK
USA300_FPR3757 LFGQRDGRPLPKIFDNDDIQRKFGIFNDDK
******************************
- ↑ Steffen Schlag, Stephan Fuchs, Christiane Nerz, Rosmarie Gaupp, Susanne Engelmann, Manuel Liebeke, Michael Lalk, Michael Hecker, Friedrich Götz
Characterization of the oxygen-responsive NreABC regulon of Staphylococcus aureus.
J Bacteriol: 2008, 190(23);7847-58
[PubMed:18820014] [WorldCat.org] [DOI] (I p)Volker Niemann, Mareike Koch-Singenstreu, Ancilla Neu, Stephanie Nilkens, Friedrich Götz, Gottfried Unden, Thilo Stehle
The NreA protein functions as a nitrate receptor in the staphylococcal nitrate regulation system.
J Mol Biol: 2014, 426(7);1539-53
[PubMed:24389349] [WorldCat.org] [DOI] (I p)Lancine Sangare, Wanbiao Chen, Chengliang Wang, Xiaobao Chen, Minhao Wu, Xuan Zhang, Jianye Zang
Structural insights into the conformational change of Staphylococcus aureus NreA at C-terminus.
Biotechnol Lett: 2020, 42(5);787-795
[PubMed:31970556] [WorldCat.org] [DOI] (I p)