⊟Summary[edit | edit source]

pan ID^?: SAUPAN003798000
symbol^?: pstS
synonym:
description^?: phosphate-binding protein
- phosphate-binding protein
- phosphate ABC transporter phosphate-binding protein PstS
- phosphate ABC transporter substrate-binding protein
- phosphate ABC transporter substrate-binding protein PstS
- phosphate ABC transporter, phosphate-binding protein
- thioredoxine reductase
- Phosphate-binding protein pstS
- Phosphate ABC transporter, periplasmic phosphate-binding protein PstS
- phosphate ABC transporter ATP-binding protein
- phosphate ABC transporter periplasmic phosphate-binding protein
- phosphate ABC transporter periplasmic protein
- phosphate binding family protein
- phosphate-binding lipoprotein
- phosphate-binding protein PstS (PBP)
strand^?: -
coordinates^?: 4090833..4091948
synteny block^?: BlockID0028550
occurrence^?: in 94% of 34 strains

pstS : phosphate-specific ABC transporter substrate-binding subunit ^[1]

Staphylococcus aureus produces three systems to acquire exogenous inorganic phosphate: PstSCAB, PitA and NtpA. While all three systems provide for inorganic phosphate import and can partially complement for loss of the other two, each has a niche role in phosphate acquisition. The PstSCAB system is highly efficient at scavenging inorganic phosphate from the environment and becomes essential when substrate availability is low.

⊟Orthologs[edit | edit source]

COL:

SACOL1424

N315:

SA1221

NCTC8325:

SAOUHSC_01389

Newman:

NWMN_1300 (pstS)

USA300_FPR3757:

SAUSA300_1283 (pstS)

JSNZ:

JSNZ_001373

04-02981:

SA2981_1343 (pstS)

08BA02176:

C248_1428

11819-97:

MS7_1346 (pstS)

6850:

RSAU_001269 (pstS)

71193:

—

ECT-R 2:

ECTR2_1246 (pstS)

ED133:

—

ED98:

SAAV_1371

HO 5096 0412:

SAEMRSA15_12530

JH1:

SaurJH1_1479

JH9:

SaurJH9_1450

JKD6008:

SAA6008_01353 (pstS)

JKD6159:

SAA6159_01256 (pstS)

LGA251:

SARLGA251_13060

M013:

M013TW_1334

MRSA252:

SAR1402

MSHR1132:

SAMSHR1132_12310

MSSA476:

SAS1330

Mu3:

SAHV_1377

Mu50:

SAV1389

MW2:

MW1277

RF122:

SAB1245c

ST398:

SAPIG1390

T0131:

SAT0131_01462

TCH60:

HMPREF0772_11819 (pstS)

TW20:

SATW20_13880

USA300_TCH1516:

USA300HOU_1324 (pstS)

VC40:

SAVC_06190

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]

alignment of orthologues:
CLUSTAL format alignment by MAFFT L-INS-i (v7.307)

COL             MKKWQFVGTTALGATLLLGACGGGNGGSGNSDLKGEAKGDGSSTVAPIVEKLNEKWAQDH
N315            MKKWQFVGTTALGATLLLGACGGGNGGSGNSDLKGEAKGDGSSTVAPIVEKLNEKWAQDH
NCTC8325        MKKWQFVGTTALGATLLLGACGGGNGGSGNSDLKGEAKGDGSSTVAPIVEKLNEKWAQDH
Newman          MKKWQFVGTTALGATLLLGACGGGNGGSGNSDLKGEAKGDGSSTVAPIVEKLNEKWAQDH
USA300_FPR3757  MKKWQFVGTTALGATLLLGACGGGNGGSGNSDLKGEAKGDGSSTVAPIVEKLNEKWAQDH
                ************************************************************

COL             SDAKISAGQAGTGAGFQKFIAGDIDFADASRPIKDEEKQKLQDKNIKYKEFKIAQDGVTV
N315            SDAKISAGQAGTGAGFQKFIAGDIDFADASRPIKDEEKQKLQDKNIKYKEFKIAQDGVTV
NCTC8325        SDAKISAGQAGTGAGFQKFIAGDIDFADASRPIKDEEKQKLQDKNIKYKEFKIAQDGVTV
Newman          SDAKISAGQAGTGAGFQKFIAGDIDFADASRPIKDEEKQKLQDKNIKYKEFKIAQDGVTV
USA300_FPR3757  SDAKISAGQAGTGAGFQKFIAGDIDFADASRPIKDEEKQKLQDKNIKYKEFKIAQDGVTV
                ************************************************************

COL             AVNKENDFVDELDKQQLKAIYSGKAKTWKDVNSKWPDKKINAVSPNSSHGTYDFFENEVM
N315            AVNKENDFVDELDKQQLKAIYSGKAKTWKDVNSKWPDKKINAVSPNSSHGTYDFFENEVM
NCTC8325        AVNKENDFVDELDKQQLKAIYSGKAKTWKDVNSKWPDKKINAVSPNSSHGTYDFFENEVM
Newman          AVNKENDFVDELDKQQLKAIYSGKAKTWKDVNSKWPDKKINAVSPNSSHGTYDFFENEVM
USA300_FPR3757  AVNKENDFVDELDKQQLKAIYSGKAKTWKDVNSKWPDKKINAVSPNSSHGTYDFFENEVM
                ************************************************************

COL             NKEDIKAEKNADTNAIVSSVTKNKEGIGYFGYNFYVQNKDKLKEVKIKDENGKATEPTKK
N315            NKEDIKAEKNADTNAIVSSVTKNKEGIGYFGYNFYVQNKDKLKEVKIKDENGKATEPTKK
NCTC8325        NKEDIKAEKNADTNAIVSSVTKNKEGIGYFGYNFYVQNKDKLKEVKIKDENGKATEPTKK
Newman          NKEDIKAEKNADTNAIVSSVTKNKEGIGYFGYNFYVQNKDKLKEVKIKDENGKATEPTKK
USA300_FPR3757  NKEDIKAEKNADTNAIVSSVTKNKEGIGYFGYNFYVQNKDKLKEVKIKDENGKATEPTKK
                ************************************************************

COL             TIQDNSYALSRPLFIYVNEKALKDNKVMSEFIKFVLEDKGKAAEEAGYVAAPEKTYKSQL
N315            TIQDNSYALSRPLFIYVNEKALKDNKVMSEFIKFVLEDKGKAAEEAGYVAAPEKTYKSQL
NCTC8325        TIQDNSYALSRPLFIYVNEKALKDNKVMSEFIKFVLEDKGKAAEEAGYVAAPEKTYKSQL
Newman          TIQDNSYALSRPLFIYVNEKALKDNKVMSEFIKFVLEDKGKAAEEAGYVAAPEKTYKSQL
USA300_FPR3757  TIQDNSYALSRPLFIYVNEKALKDNKVMSEFIKFVLEDKGKAAEEAGYVAAPEKTYKSQL
                ************************************************************

COL             DDLKAFIDKNQKSDDKKSDDKKSEDKK
N315            DDLKAFIDKNQKSDDKKSDDKKSEDKK
NCTC8325        DDLKAFIDKNQKSDDKKSDDKKSEDKK
Newman          DDLKAFIDKNQKSDDKKSDDKKSEDKK
USA300_FPR3757  DDLKAFIDKNQKSDDKKSDDKKSEDKK
                ***************************

↑ Jessica L Kelliher, Jana N Radin, Kyle P Grim, Paola K Párraga Solórzano, Patrick H Degnan, Thomas E Kehl-Fie
Acquisition of the Phosphate Transporter NptA Enhances Staphylococcus aureus Pathogenesis by Improving Phosphate Uptake in Divergent Environments.
Infect Immun: 2018, 86(1);
[PubMed:29084897] [WorldCat.org] [DOI] (I e)

[1] Jessica L Kelliher, Jana N Radin, Kyle P Grim, Paola K Párraga Solórzano, Patrick H Degnan, Thomas E Kehl-Fie
Acquisition of the Phosphate Transporter NptA Enhances Staphylococcus aureus Pathogenesis by Improving Phosphate Uptake in Divergent Environments.
Infect Immun: 2018, 86(1);
[PubMed:29084897] [WorldCat.org] [DOI] (I e)

[1]

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Contents

⊟Summary[edit | edit source]

⊟Orthologs[edit | edit source]

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757
JSNZ

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⊟Summary[edit | edit source]

⊟Orthologs[edit | edit source]

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]