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⊟Summary[edit | edit source]
- pan ID?: SAUPAN003043000
- symbol?: —
- synonym:
- description?: Na+/H+ antiporter family protein
- Na+/H+ antiporter family protein
- sodium:proton antiporter
- permease, putative
- citrate transporter family protein
- dctM-like transporters family protein
- Histidine permease YuiF
- Na+/H+ antiporter NhaC
- Na+ antiporter NhaC
- NhaC family Na(+)/H(+) antiporter
- NhaC family sodium:proton (Na+:H+) antiporter
- NhaC family sodium antiporter
- putative transporter protein
- transporter
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 3433423..3434760
- synteny block?: BlockID0021510
- occurrence?: in 100% of 34 strains
yuiF (nhaC3, nhaK2) : primary histidine transporter and alkaline monovalent cation:proton antiporter [1]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0898 (yuiF)
08BA02176:
C248_0942
11819-97:
MS7_0898
6850:
RSAU_000820
71193:
ST398NM01_0926
ECT-R 2:
ECTR2_799
ED133:
SAOV_0889
ED98:
SAAV_0904
HO 5096 0412:
SAEMRSA15_07730
JH1:
SaurJH1_0962
JH9:
SaurJH9_0943
JKD6008:
SAA6008_00896
JKD6159:
SAA6159_00802
JSNZ:
JSNZ_000906
LGA251:
SARLGA251_08610
M013:
M013TW_0862
MRSA252:
SAR0905
MSHR1132:
SAMSHR1132_07950
MSSA476:
SAS0813
Mu3:
SAHV_0938
Mu50:
SAV0943
MW2:
MW0825
RF122:
SAB0809
ST398:
SAPIG0926
T0131:
SAT0131_00975 (ftsW)
TCH60:
HMPREF0772_12304
TW20:
SATW20_09430
USA300_TCH1516:
USA300HOU_0903
VC40:
SAVC_03890
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MINAVVIAVILMIMLCLCRLNVVISLFISALVGGLISGMSIEKVINVFGKNIVDGAEVAL
N315 MINAVVIAVILMIVLCLCRLNVVISLFISALVGGLISGMSIEKVINVFGKNIVDGAEVAL
NCTC8325 MINAVVIAVILMIVLCLCRLNVVISLFISALVGGLISGMSIEKVINVFGKNIVDGAEVAL
Newman MINAVVIAVILMIVLCLCRLNVVISLFISALVGGLISGMSIEKVINVFGKNIVDGAEVAL
USA300_FPR3757 MINAVVIAVILMIVLCLCRLNVVISLFISALVGGLISGMSIEKVINVFGKNIVDGAEVAL
*************:**********************************************
COL SYALLGGFAALISYSGITDYLVGKIINAIHAENSRWSRVKVKVTIIIALLAMSIMSQNLI
N315 SYALLGGFAALISYSGITDYLVGKIINAIHAENSRWSRVKVKVTIIIALLAMSIMSQNLI
NCTC8325 SYALLGGFAALISYSGITDYLVGKIINAIHAENSRWSRVKVKVTIIIALLAMSIMSQNLI
Newman SYALLGGFAALISYSGITDYLVGKIINAIHAENSRWSRVKVKVTIIIALLAMSIMSQNLI
USA300_FPR3757 SYALLGGFAALISYSGITDYLVGKIINAIHAENSRWSRVKVKVTIIIALLAMSIMSQNLI
************************************************************
COL PVHIAFIPIVIPPLLSLFNDLKIDRRLIGLIIGFGLCFPYVLLPYGFGQIFQQIIQSGFA
N315 PVHIAFIPIVIPPLLSLFNDLKIDRRLIGLIIGFGLCFPYVLLPYGFGQIFQQIIQSGFA
NCTC8325 PVHIAFIPIVIPPLLSLFNDLKIDRRLIGLIIGFGLCFPYVLLPYGFGQIFQQIIQSGFA
Newman PVHIAFIPIVIPPLLSLFNDLKIDRRLIGLIIGFGLCFPYVLLPYGFGQIFQQIIQSGFA
USA300_FPR3757 PVHIAFIPIVIPPLLSLFNDLKIDRRLIGLIIGFGLCFPYVLLPYGFGQIFQQIIQSGFA
************************************************************
COL KANHPIEFNMIWKAMLIPSMGYIVGLLIGLYVYRKPREYETRKISDSDNVTELKPYILIV
N315 KANHPIEFNMIWKAMLIPSMGYIVGLLIGLYVYRKPREYETRKISDSDNVTELKPYILIV
NCTC8325 KANHPIEFNMIWKAMLIPSMGYIVGLLIGLYVYRKPREYETRKISDSDNVTELKPYILIV
Newman KANHPIEFNMIWKAMLIPSMGYIVGLLIGLYVYRKPREYETRKISDSDNVTELKPYILIV
USA300_FPR3757 KANHPIEFNMIWKAMLIPSMGYIVGLLIGLYVYRKPREYETRKISDSDNVTELKPYILIV
************************************************************
COL TIVAILATFLVQTFTDSMIFGALAGVLVFFISRAYNWYELDAKFVEGIKIMAYIGVVILT
N315 TIVAILATFLVQTFTDSMIFGALAGVLVFFISRAYNWYELDAKFVEGIKIMAYIGVVILT
NCTC8325 TIVAILATFLVQTFTDSMIFGALAGVLVFFISRAYNWYELDAKFVEGIKIMAYIGVVILT
Newman TIVAILATFLVQTFTDSMIFGALAGVLVFFISRAYNWYELDAKFVEGIKIMAYIGVVILT
USA300_FPR3757 TIVAILATFLVQTFTDSMIFGALAGVLVFFISRAYNWYELDAKFVEGIKIMAYIGVVILT
************************************************************
COL ANGFAGVMNATGDIDELVKTLTSITGDNKLFSIIMMYVIGLIVTLGIGSSFATIPIIASL
N315 ANGFAGVMNATGDIDELVKTLTSITGDNKLFSIIMMYVIGLIVTLGIGSSFATIPIIASL
NCTC8325 ANGFAGVMNATGDIDELVKTLTSITGDNKLFSIIMMYVIGLIVTLGIGSSFATIPIIASL
Newman ANGFAGVMNATGDIDELVKTLTSITGDNKLFSIIMMYVIGLIVTLGIGSSFATIPIIASL
USA300_FPR3757 ANGFAGVMNATGDIDELVKTLTSITGDNKLFSIIMMYVIGLIVTLGIGSSFATIPIIASL
************************************************************
COL FIPFGASIGLDTMALIALIGTASALGDSGSPASDSTLGPTAGLNVDGQHDHIRDTCVPNF
N315 FIPFGASIGLDTMALIALIGTASALGDSGSPASDSTLGPTAGLNVDGQHDHIRDTCVPNF
NCTC8325 FIPFGASIGLDTMALIALIGTASALGDSGSPASDSTLGPTAGLNVDGQHDHIRDTCVPNF
Newman FIPFGASIGLDTMALIALIGTASALGDSGSPASDSTLGPTAGLNVDGQHDHIRDTCVPNF
USA300_FPR3757 FIPFGASIGLDTMALIALIGTASALGDSGSPASDSTLGPTAGLNVDGQHDHIRDTCVPNF
************************************************************
COL LFYNIPLMIFGTIAAMVL
N315 LFYNIPLMIFGTIAAMVL
NCTC8325 LFYNIPLMIFGTIAAMVL
Newman LFYNIPLMIFGTIAAMVL
USA300_FPR3757 LFYNIPLMIFGTIAAMVL
******************
- ↑ Catrin M Beetham, Christopher F Schuster, Igor Kviatkovski, Marina Santiago, Suzanne Walker, Angelika Gründling
Histidine transport is essential for the growth of Staphylococcus aureus at low pH.
PLoS Pathog: 2024, 20(1);e1011927
[PubMed:38227607] [WorldCat.org] [DOI] (I e)Manisha Vaish, Alexa Price-Whelan, Tamara Reyes-Robles, Jun Liu, Amyeo Jereen, Stephanie Christie, Francis Alonzo, Meredith A Benson, Victor J Torres, Terry A Krulwich
Roles of Staphylococcus aureus Mnh1 and Mnh2 Antiporters in Salt Tolerance, Alkali Tolerance, and Pathogenesis.
J Bacteriol: 2018, 200(5);
[PubMed:29263099] [WorldCat.org] [DOI] (I e)Dylan Casey, Roy D Sleator
A genomic analysis of osmotolerance in Staphylococcus aureus.
Gene: 2021, 767;145268
[PubMed:33157201] [WorldCat.org] [DOI] (I p)German A Ashniev, Natalia V Sernova, Aleksei E Shevkoplias, Ivan D Rodionov, Irina A Rodionova, Alexey G Vitreschak, Mikhail S Gelfand, Dmitry A Rodionov
Evolution of transcriptional regulation of histidine metabolism in Gram-positive bacteria.
BMC Genomics: 2022, 23(Suppl 6);558
[PubMed:36008760] [WorldCat.org] [DOI] (I e)