PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary

• pan ID^?: SAUPAN002122000
• symbol^?: hsdS1
• synonym:
• description^?: restriction endonuclease subunit S

  descriptions from strain specific annotations:

  • restriction endonuclease subunit S
  • restriction modification system specificity subunit
  • putative restriction/modification system specificity protein
  • type I restriction modification system, site specificity determination subunit
  • type I restriction-modification system, S subunit
  • type I restriction-modification system S subunit
  • EcoA family type I restriction-modification system
  • restriction and modification system specificity protein
  • restriction endonuclease S subunit
  • Restriction modification system DNA specificity domain protein
  • restriction modification system DNA specificity subunit
  • type I restriction modification DNA specificity domain protein
  • Type I restriction-modification system, specificity subunit S
  • type I restriction-modification system specificity protein
  • type I restriction-modification system subunit S
  • type I site-specific deoxyribonuclease specificity subunit
• strand^?: +
• coordinates^?: 2613264..2615281
• synteny block^?: BlockID0014280
• occurrence^?: in 62% of 34 strains

⊟Orthologs

COL:
SACOL0477
N315:
SA0392 (hsdS)
NCTC8325:
SAOUHSC_00398
Newman:
NWMN_0399 (hsdS)
USA300_FPR3757:
SAUSA300_0406
JSNZ:
JSNZ_000367
04-02981:
SA2981_0408 (hsdS)
08BA02176:
—
11819-97:
—
6850:
RSAU_000361
71193:
—
ECT-R 2:
ECTR2_367
ED133:
—
ED98:
SAAV_0375 (hsdS1)
HO 5096 0412:
—
JH1:
SaurJH1_0467
JH9:
SaurJH9_0455
JKD6008:
SAA6008_00435 (hsdS)
JKD6159:
—
LGA251:
—
M013:
—
MRSA252:
SAR0434
MSHR1132:
—
MSSA476:
—
Mu3:
SAHV_0430 (hsdS)
Mu50:
SAV0432 (hsdS)
MW2:
—
RF122:
—
ST398:
—
T0131:
SAT0131_00471
TCH60:
HMPREF0772_10085
TW20:
SATW20_05090
USA300_TCH1516:
USA300HOU_0434 (hsdS1)
VC40:
SAVC_01790

⊟Genome Viewer

COL
N315
NCTC8325
Newman
USA300_FPR3757
JSNZ

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
  
  
  COL             MSNTQKKNVPELRFPGFEGEWEEKQLGDLTDRVIRKNKNLESKKPLTISGQLGLIDQTEY
  N315            MSNTQKKNVPELRFPGFEGEWEEKQLGDLTDRVIRKNKNLESKKPLTISGQLGLIDQTEY
  NCTC8325        MSNTQKKNVPELRFPGFEGEWEEKQLGDLTDRVIRKNKNLESKKPLTISGQLGLIDQTEY
  Newman          MSNTQKKNVPELRFPGFEGEWEEKQLGDLTDRVIRKNKNLESKKPLTISGQLGLIDQTEY
  USA300_FPR3757  MSNTQKKNVPELRFPGFEGEWEEKQLGDLTDRVIRKNKNLESKKPLTISGQLGLIDQTEY
  JSNZ            MSNTQTKNVPELKFPEFEGEWEEKKLGEFAGKVTKKNVDKKYIETLTNSAELGIISQKDY
                  *****.******:** ********:**:::.:* :** : :  :.** *.:**:*.*.:*
  
  COL             FSKSVSS-KNLENYTLIKNGEFAYNKSYSNGYPLGAIKRLTRYDSGVLSSLYICFSIKSE
  N315            FSKSVSS-KNLENYTLIKNGEFAYNKSYSNGYPLGAIKRLTRYDSGVLSSLYICFSIKSE
  NCTC8325        FSKSVSS-KNLENYTLIKNGEFAYNKSYSNGYPLGAIKRLTRYDSGVLSSLYICFSIKSE
  Newman          FSKSVSS-KNLENYTLIKNGEFAYNKSYSNGYPLGAIKRLTRYDSGVLSSLYICFSIKSE
  USA300_FPR3757  FSKSVSS-KNLENYTLIKNGEFAYNKSYSNGYPLGAIKRLTRYDSGVLSSLYICFSIKSE
  JSNZ            FDKEISNIDNIKKYYVVEENDFVYNPRISNYAPFGPVNRNKLGKKGVMSPLYTVFKIQN-
                  *.*.:*. .*:::* ::::.:*.**   **  *:*.::* .  ..**:*.**  *.*:. 
  
  COL             MSKDFMEAYFDSTHWYREVSGIAVEGARNHGLLNVSVNDFFTILIKYPSLEEQQKIGKFF
  N315            MSKDFMEAYFDSTHWYREVSGIAVEGARNHGLLNVSVNDFFTILIKYPSLEEQQKIGKFF
  NCTC8325        MSKDFMEAYFDSTHWYREVSGIAVEGARNHGLLNVSVNDFFTILIKYPSLEEQQKIGKFF
  Newman          MSKDFMEAYFDSTHWYREVSGIAVEGARNHGLLNVSVNDFFTILIKYPSLEEQQKIGKFF
  USA300_FPR3757  MSKDFMEAYFDSTHWYREVSGIAVEGARNHGLLNVSVNDFFTILIKYPSLEEQQKIGKFF
  JSNZ            IDLNFIEFYFKSSKWYRFMALNGDSGARAD-RFSIKNRTFMEMPLHIPCMDEQIKIGQFF
                  :. :*:* **.*::*** ::  . .*** .  :.:. . *: : :: *.::** ***:**
  
  COL             SKLDRQIELEEQKLELLQQQKKGYMQKIFSQELRFKDENGEDYPDWENSKIEKYLKERNE
  N315            SKLDRQIELEEQKLELLQQQKKGYMQKIFSQELRFKDENGEDYPDWENSKIEKYLKERNE
  NCTC8325        SKLDRQIELEEQKLELLQQQKKGYMQKIFSQELRFKDENGEDYPDWENSKIEKYLKERNE
  Newman          SKLDRQIELEEQKLELLQQQKKGYMQKIFSQELRFKDENGEDYPDWENSKIEKYLKERNE
  USA300_FPR3757  SKLDRQIELEEQKLELLQQQKKGYMQKIFSQELRFKDENGEDYPDWENSKIEKYLKERNE
  JSNZ            SKLDRQIELEEQKLELLQQQKKGYMQKIFSQELRFKDENGNDYPEWEERRFADIFKFHNK
                  ****************************************:***:**: :: . :* :*:
  
  COL             -RSDKGQMLSVTIN------SGIIKFSELDRKDNS----SKDKSNYKVVRKNDIAYNSMR
  N315            -RSDKGQMLSVTIN------SGIIKFSELDRKDNS----SKDKSNYKVVRKNDIAYNSMR
  NCTC8325        -RSDKGQMLSVTIN------SGIIKFSELDRKDNS----SKDKSNYKVVRKNDIAYNSMR
  Newman          -RSDKGQMLSVTIN------SGIIKFSELDRKDNS----SKDKSNYKVVRKNDIAYNSMR
  USA300_FPR3757  -RSDKGQMLSVTIN------SGIIKFSELDRKDNS----SKDKSNYKVVRKNDIAYNSMR
  JSNZ            LRKPIKENLRVKGSYPYYGATGIIDYVDDFIFDGNYLLIGEDGANI-ITRSAPLVY----
                   *.   : * *. .      :***.: :    *..    .:* :*  :.*.  :.*    
  
  COL             MWQGASGKSNYNGIVSPAYTVLYPTQNTSSLFIGYKFKTHRMIHKFKINSQGLTSDTWNL
  N315            MWQGASGKSNYNGIVSPAYTVLYPTQNTSSLFIGYKFKTHRMIHKFKINSQGLTSDTWNL
  NCTC8325        MWQGASGKSNYNGIVSPAYTVLYPTQNTSSLFIGYKFKTHRMIHKFKINSQGLTSDTWNL
  Newman          MWQGASGKSNYNGIVSPAYTVLYPTQNTSSLFIGYKFKTHRMIHKFKINSQGLTSDTWNL
  USA300_FPR3757  MWQGASGKSNYNGIVSPAYTVLYPTQNTSSLFIGYKFKTHRMIHKFKINSQGLTSDTWNL
  JSNZ            LVNGKFWVNNHAHILSPL-----------NGNIQYLYQVAELVNYEKYNT---GTAQPKL
                  : :*    .*:  *:**            .  * * ::. .:::  * *:    :   :*
  
  COL             KYKQLKNINIDIPV-LEEQEKIGDFFKKMDILISKQKMKIEILEKEKQSFLQKMFL
  N315            KYKQLKNINIDIPV-LEEQEKIGDFFKKMDILISKQKMKIEILEKEKQSFLQKMFL
  NCTC8325        KYKQLKNINIDIPV-LEEQEKIGDFFKKMDILISKQKMKIEILEKEKQSFLQKMFL
  Newman          KYKQLKNINIDIPV-LEEQEKIGDFFKKMDILISKQKMKIEILEKEKQSFLQKMFL
  USA300_FPR3757  KYKQLKNINIDIPV-LEEQEKIGDFFKKMDILISKQKMKIEILEKEKQSFLQKMFL
  JSNZ            NIQNLKIISVVISTNLEEQQKIGSFLSKLDRQIDLEEQKLELLQQRKKALLKSMFV
                  : ::** *.: *.. ****:***.*:.*:*  *. :: *:*:*::.*:::*:.**: