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PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000367
  • pan locus tag?: SAUPAN002122000
  • symbol: JSNZ_000367
  • pan gene symbol?: hsdS1
  • synonym:
  • product: restriction endonuclease subunit S

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000367
  • symbol: JSNZ_000367
  • product: restriction endonuclease subunit S
  • replicon: chromosome
  • strand: +
  • coordinates: 400023..401210
  • length: 1188
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGAGTAATACACAAACGAAAAATGTGCCAGAGTTGAAATTCCCAGAGTTTGAAGGCGAA
    TGGGAAGAGAAGAAGCTAGGGGAATTTGCTGGTAAAGTTACAAAAAAAAATGTTGATAAA
    AAATATATTGAGACATTAACTAATTCAGCTGAGTTAGGTATCATATCTCAAAAGGATTAT
    TTTGACAAAGAAATTTCGAATATAGATAATATTAAAAAGTACTATGTAGTTGAAGAGAAT
    GATTTTGTTTATAATCCTAGAATTTCTAATTATGCTCCATTTGGACCAGTAAATAGAAAT
    AAGTTAGGGAAAAAAGGGGTCATGTCACCTCTTTATACTGTGTTTAAAATTCAAAATATT
    GATTTAAACTTTATTGAGTTTTATTTTAAATCATCAAAATGGTATAGATTTATGGCATTA
    AACGGTGATTCAGGTGCTCGAGCAGATAGGTTTTCTATTAAAAATAGGACATTTATGGAA
    ATGCCACTTCATATCCCATGTATGGATGAACAAATAAAAATCGGTCAGTTCTTCAGCAAA
    CTCGACCGACAAATTGAATTAGAAGAACAAAAACTCGAATTACTTCAACAACAGAAAAAA
    GGCTATATGCAGAAAATTTTCTCACAGGAACTGAGATTTAAAGATGAGAATGGTAATGAT
    TATCCGGAGTGGGAAGAGAGAAGATTTGCTGATATATTTAAATTTCATAATAAACTAAGA
    AAGCCAATTAAAGAAAATTTAAGAGTAAAGGGTTCTTATCCATATTATGGTGCTACAGGT
    ATTATTGATTACGTTGACGACTTTATATTTGACGGGAATTATTTACTTATTGGAGAAGAT
    GGTGCAAATATTATCACTAGAAGTGCACCCCTAGTGTACTTAGTAAATGGAAAGTTTTGG
    GTAAATAATCATGCTCATATATTATCTCCTTTAAATGGAAATATACAGTACTTGTATCAA
    GTTGCAGAATTAGTTAATTATGAAAAATACAATACTGGAACTGCTCAGCCTAAATTAAAC
    ATTCAAAATTTAAAAATTATTAGTGTTGTAATTTCAACGAATTTAGAAGAACAACAAAAA
    ATCGGAAGCTTTTTAAGTAAACTTGATCGTCAAATCGATTTAGAAGAACAAAAACTCGAA
    TTACTTCAACAACGAAAAAAAGCCTTACTTAAATCGATGTTTGTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1188

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000367
  • symbol: JSNZ_000367
  • description: restriction endonuclease subunit S
  • length: 395
  • theoretical pI: 9.05577
  • theoretical MW: 46357.7
  • GRAVY: -0.577468

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    TRD (CL0477) Methylase_S; Type I restriction modification DNA specificity domain (PF01420; HMM-score: 125.8)
    and 4 more
    T3SS-Chaperone (CL0419) FliJ; Flagellar FliJ protein (PF02050; HMM-score: 12.4)
    no clan defined DUF4140; N-terminal domain of unknown function (DUF4140) (PF13600; HMM-score: 12.2)
    DUF5384; Family of unknown function (DUF5384) (PF17358; HMM-score: 9)
    SieB; Super-infection exclusion protein B (PF14163; HMM-score: 6.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.811
    • Cytoplasmic Membrane Score: 0.0046
    • Cell wall & surface Score: 0.0022
    • Extracellular Score: 0.1822
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004836
    • TAT(Tat/SPI): 0.000659
    • LIPO(Sec/SPII): 0.000629
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSNTQTKNVPELKFPEFEGEWEEKKLGEFAGKVTKKNVDKKYIETLTNSAELGIISQKDYFDKEISNIDNIKKYYVVEENDFVYNPRISNYAPFGPVNRNKLGKKGVMSPLYTVFKIQNIDLNFIEFYFKSSKWYRFMALNGDSGARADRFSIKNRTFMEMPLHIPCMDEQIKIGQFFSKLDRQIELEEQKLELLQQQKKGYMQKIFSQELRFKDENGNDYPEWEERRFADIFKFHNKLRKPIKENLRVKGSYPYYGATGIIDYVDDFIFDGNYLLIGEDGANIITRSAPLVYLVNGKFWVNNHAHILSPLNGNIQYLYQVAELVNYEKYNTGTAQPKLNIQNLKIISVVISTNLEEQQKIGSFLSKLDRQIDLEEQKLELLQQRKKALLKSMFV

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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