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NCBI: 03-AUG-2016

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_02888
  • pan locus tag?: SAUPAN006236000
  • symbol: SAOUHSC_02888
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Additional information (user-provided)[edit | edit source]

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_02888
  • symbol: SAOUHSC_02888
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2661993..2663048
  • length: 1056
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGACATCAATTAAAACAATTACACCCAAAGATTTTATATTTAGAGTTTTATCAGGTGTC
    GCCATAGGTATTGTTGCGGGTTTAGTTCCTAATGCGATACTTGGAGAAATTTTTAAATAC
    TTTATGGATTATCATCCGATTTTTAAAACGTTATTAGGCGTTGTCGTTGCAATTCAATTT
    ACAGTACCTGCTTTGATTGGTGCATTGGTTGCCATGAAATTTGACCTATCGCCATTAGCA
    ATTGCTGTTGTGGCAAGTGCAGCATATGTAGGAAGCGGTGCAGCGCAGTTTAAAAATGGT
    GCTTGGATGATTACGGGTATTGGTGATTTAATTAATACAATGATTACAGCAGCGATTGCA
    GTGTTATTCATTTTACTTATTCAACATCGCGTAGGTAGTATGGCATTGATTGTATTCCCA
    ACAGTTGTTGGCGGTATTTCAGGTGCAATTGGTGTTTTAATATTGCCGTATACGAAAATG
    ATTACAACAGCCATCGGTAATATGGTTAATGGTTTTACAGAATTACAACCGATTGTCATG
    AGTATTTTGATTTCAATGGTATTTAGTCTTATTATTATTTCGCCACTATCAACTGTGGCC
    ATTGCCTTTGCGATAGGTATTACAGGTTTAGCAGCTGGATCAGCGTCAATTGGTATCTCC
    GCGACTGAAGCAGTATTGATAATTGGTACAAGTAAAGTGAATCGTTTAGGGGTGCCGTTA
    TCCGTCTTCTTTGGAGGCGTTAAAATGATGATACCTAATATGGTGAAATATCCAATTCTT
    ATGTTACCAATATTAACGACAGCCATTGTATCAGGTTTGGTATCAGCATTAGTAGGTATT
    CATGGAACGAAAGAGTCAGCTGGATTTGGTTTTATAGGAATGGTAGGACCGATTAATGCA
    TTTAAATTTATGGAGGTTGATTCTGCTTGGTTGAGTGTCTTACTAATTGTAGTAGCGTTC
    TTTGTTGTACCATTTGTAACAGCTTGGCTTGCAGATATCATTTATCGTAAAGTGTTTCGT
    TTATATACTAATGATATTTTTAAATTCATGGGATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1056


⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAOUHSC_02888
  • symbol: SAOUHSC_02888
  • description: hypothetical protein
  • length: 351
  • theoretical pI: 10.121
  • theoretical MW: 37016.6
  • GRAVY: 1.21225

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Membrane protein
  • PFAM:
    PTS_EIIC (CL0493) PTS_EIIC_2; Phosphotransferase system, EIIC (PF13303; HMM-score: 362.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0003
    • Cytoplasmic Membrane Score: 0.998
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0017
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.017385
    • TAT(Tat/SPI): 0.008033
    • LIPO(Sec/SPII): 0.010335
  • predicted transmembrane helices (TMHMM): 10

⊟Accession numbers[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTSIKTITPKDFIFRVLSGVAIGIVAGLVPNAILGEIFKYFMDYHPIFKTLLGVVVAIQFTVPALIGALVAMKFDLSPLAIAVVASAAYVGSGAAQFKNGAWMITGIGDLINTMITAAIAVLFILLIQHRVGSMALIVFPTVVGGISGAIGVLILPYTKMITTAIGNMVNGFTELQPIVMSILISMVFSLIIISPLSTVAIAFAIGITGLAAGSASIGISATEAVLIIGTSKVNRLGVPLSVFFGGVKMMIPNMVKYPILMLPILTTAIVSGLVSALVGIHGTKESAGFGFIGMVGPINAFKFMEVDSAWLSVLLIVVAFFVVPFVTAWLADIIYRKVFRLYTNDIFKFMG

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CodY* (repression) regulon
    CodY*(TF)important in Amino acid metabolism; RegPrecise 

⊟Additional information (user-provided)[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Other information (user-provided)[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ 1.0 1.1 Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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