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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS11565 [old locus tag: SACOL2198 ]
  • pan locus tag?: SAUPAN005624000
  • symbol: SACOL_RS11565
  • pan gene symbol?: budA1
  • synonym:
  • product: alpha-acetolactate decarboxylase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS11565 [old locus tag: SACOL2198 ]
  • symbol: SACOL_RS11565
  • product: alpha-acetolactate decarboxylase
  • replicon: chromosome
  • strand: -
  • coordinates: 2279672..2280376
  • length: 705
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (2279672..2280376) NCBI
  • BioCyc: SACOL_RS11565 BioCyc
  • MicrobesOnline: see SACOL2198

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
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    541
    601
    661
    ATGACTAATGTTTTATACCAACATGGTACATTAGGCACATTAATGGCAGGATTATTAAAA
    GGAACTGCATCAATAAATGAATTATTGCAACATGGTGACTTAGGTATCGCTACACTAACA
    GGTTCAAACGGTGAGGTAATCTTTTTAGATGGAAAAGCTTACCATGCAAATGAACATAAA
    GAATTTGTAGAATTAAAAGGTGACGAGTTAACACCATATGCAACTGTAACTAAATTTGTA
    GCAGATACAAGCTATGAAACGAAAGATAAATCTTCAGAAGCAGTTTTTGCAGAAATTAAG
    GAAAAGATGTTGAGTGAAAATTTATTTTCAGCAGTAAAAATTTCAGGCTTATTTAAAAAA
    ATGCATGTACGTATGATGCCGGCTCAAGAACCACCTTATACACGTTTAATCGATTCAGCT
    AGAAGACAACCTGAACAAACTGAAACGTATGTCAAAGGTTCAGTCGTTGGTTTCTTTACA
    CCAGAATTATTCCATGGTATCGGATCAGCAGGATTTCATGTACACTTTGCGAATGATGAT
    CGTAACTTTGGTGGACATGTCTTAGATTTTGAAGTAGAAGATGTTAAAGTAGAAATCCAA
    AATATAGAAACATTTGAACAGCATTTTCCAATTCAAGATAAAGATTTCACTAAAGCAAAT
    ATTGACTATAAAGATATTGCAGACGAAATTAGAGAAGCTGAATAA
    60
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    360
    420
    480
    540
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    660
    705

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS11565 [old locus tag: SACOL2198 ]
  • symbol: SACOL_RS11565
  • description: alpha-acetolactate decarboxylase
  • length: 234
  • theoretical pI: 4.83309
  • theoretical MW: 26223.3
  • GRAVY: -0.363675

⊟Function[edit | edit source]

  • reaction:
    EC 4.1.1.5?  ExPASy
    Acetolactate decarboxylase (2S)-2-hydroxy-2-methyl-3-oxobutanoate = (3R)-3-hydroxybutan-2-one + CO2
  • TIGRFAM:
    Metabolism Energy metabolism Fermentation alpha-acetolactate decarboxylase (TIGR01252; EC 4.1.1.5; HMM-score: 251.5)
  • TheSEED: see SACOL2198
  • PFAM:
    ALDC (CL0615) AAL_decarboxy; Alpha-acetolactate decarboxylase (PF03306; HMM-score: 254.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9938
    • Cytoplasmic Membrane Score: 0
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0062
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.055983
    • TAT(Tat/SPI): 0.003158
    • LIPO(Sec/SPII): 0.043243
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTNVLYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNGEVIFLDGKAYHANEHKEFVELKGDELTPYATVTKFVADTSYETKDKSSEAVFAEIKEKMLSENLFSAVKISGLFKKMHVRMMPAQEPPYTRLIDSARRQPEQTETYVKGSVVGFFTPELFHGIGSAGFHVHFANDDRNFGGHVLDFEVEDVKVEIQNIETFEQHFPIQDKDFTKANIDYKDIADEIREAE

⊟Experimental data[edit | edit source]

  • experimentally validated: see SACOL2198
  • protein localization: see SACOL2198
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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