From AureoWiki
Jump to navigation Jump to search

NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS07890 [old locus tag: SACOL1549 ]
  • pan locus tag?: SAUPAN004039000
  • symbol: SACOL_RS07890
  • pan gene symbol?: zwf
  • synonym:
  • product: glucose-6-phosphate dehydrogenase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS07890 [old locus tag: SACOL1549 ]
  • symbol: SACOL_RS07890
  • product: glucose-6-phosphate dehydrogenase
  • replicon: chromosome
  • strand: +
  • coordinates: 1584167..1585651
  • length: 1485
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (1584167..1585651) NCBI
  • BioCyc: SACOL_RS07890 BioCyc
  • MicrobesOnline: see SACOL1549

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    TTGAGTACTAAAAACAAACACATCCCATGTTTAATCACAATCTTTGGTGCAACTGGTGAC
    TTAAGCCATCGTAAGTTGTTTCCATCAATATTCCATCTCTACCAACAAGACAATTTAGAT
    GAACATATTGCCATCATCGGTATTGGACGTCGTGACATTACTAATGATGATTTCCGTAAT
    CAAGTAAAATCATCAATTCAAAAGCACGTAAAAGATACAAACAAAATTGACGCGTTTATG
    GAACATGTCTTCTATCATAGACATGATGTTAGTAATGAAGAAAGCTATCAAGAATTACTA
    GATTTTAGTAATGAATTAGATAGCCAATTTGAATTAAAAGGTAATCGACTATTCTATTTA
    GCAATGGCACCACAATTCTTTGGCGTTATTTCTGATTATCTAAAATCTTCTGGTCTTACT
    GATACAAAAGGATTTAAACGCCTTGTTATCGAAAAACCATTCGGTAGTGATTTAAAATCA
    GCCGAAGCATTAAACAATCAAATTCGTAAATCATTTAAAGAAGAAGAAATTTATCGTATT
    GACCACTATTTAGGAAAAGACATGGTTCAAAATATCGAGGTATTACGTTTTGCGAATGCG
    ATGTTTGAACCATTATGGAATAACAAATATATTTCAAACATCCAAGTTACATCTTCTGAA
    ATACTAGGTGTTGAAGATCGTGGTGGTTATTATGAATCAAGTGGCGCGCTAAAAGATATG
    GTGCAAAACCACATGTTACAAATGGTTGCATTATTAGCTATGGAAGCACCTATTAGTTTA
    AATAGTGAAGATATCCGTGCTGAGAAAGTAAAAGTACTTAAATCACTGCGTCATTTCCAA
    TCTGAAGATGTTAAAAAGAACTTTGTTCGTGGTCAATATGGCGAAGGCTATATCGATGGT
    AAACAAGTTAAAGCATACCGTGATGAAGATCGCGTTGCAGATGACTCTAACACACCTACC
    TTTGTTTCAGGTAAATTAACAATTGATAACTTTAGATGGGCTGGTGTACCATTCTATATT
    CGTACTGGTAAACGTATGAAATCTAAAACAATTCAAGTTGTCGTTGAATTTAAAGAAGTA
    CCAATGAACTTATACTATGAAACTGATAAACTGTTAGATTCAAACCTATTAGTAATCAAT
    ATCCAACCTAATGAAGGTGTATCTTTACATCTAAATGCTAAGAAAAATACACAAGGTATC
    GAAACAGAACCTGTCCAATTGTCTTACTCAATGAGCGCTCAAGATAAAATGAATACTGTA
    GATGCATATGAAAATCTATTATTTGATTGTCTTAAAGGTGATGCCACTAACTTCACGCAC
    TGGGAAGAATTAAAATCAACATGGAAATTTGTTGATGCAATTCAAGATGAATGGAATATG
    GTTGATCCAGAATTCCCTAACTATGAATCAGGTACTAATGGTCCATTAGAAAGTGATTTA
    CTACTTGCTCGTGATGGTAACCATTGGTGGGACGATATTCAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1485

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS07890 [old locus tag: SACOL1549 ]
  • symbol: SACOL_RS07890
  • description: glucose-6-phosphate dehydrogenase
  • length: 494
  • theoretical pI: 5.18811
  • theoretical MW: 56964.8
  • GRAVY: -0.531377

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 1.1.1.49?  ExPASy
    Glucose-6-phosphate dehydrogenase (NADP+) D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH
  • TIGRFAM:
    Metabolism Energy metabolism Pentose phosphate pathway glucose-6-phosphate dehydrogenase (TIGR00871; EC 1.1.1.49; HMM-score: 635.3)
  • TheSEED: see SACOL1549
  • ⊞PFAM:
    GADPH_aa-bio_dh (CL0139) G6PD_C; Glucose-6-phosphate dehydrogenase, C-terminal domain (PF02781; HMM-score: 396)
    and 2 more
    NADP_Rossmann (CL0063) G6PD_N; Glucose-6-phosphate dehydrogenase, NAD binding domain (PF00479; HMM-score: 217)
    no clan defined DUF3775; Protein of unknown function (DUF3775) (PF12616; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9181
    • Cytoplasmic Membrane Score: 0.0221
    • Cell wall & surface Score: 0.0059
    • Extracellular Score: 0.0539
  • LocateP:
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.023101
    • TAT(Tat/SPI): 0.000621
    • LIPO(Sec/SPII): 0.034757
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSTKNKHIPCLITIFGATGDLSHRKLFPSIFHLYQQDNLDEHIAIIGIGRRDITNDDFRNQVKSSIQKHVKDTNKIDAFMEHVFYHRHDVSNEESYQELLDFSNELDSQFELKGNRLFYLAMAPQFFGVISDYLKSSGLTDTKGFKRLVIEKPFGSDLKSAEALNNQIRKSFKEEEIYRIDHYLGKDMVQNIEVLRFANAMFEPLWNNKYISNIQVTSSEILGVEDRGGYYESSGALKDMVQNHMLQMVALLAMEAPISLNSEDIRAEKVKVLKSLRHFQSEDVKKNFVRGQYGEGYIDGKQVKAYRDEDRVADDSNTPTFVSGKLTIDNFRWAGVPFYIRTGKRMKSKTIQVVVEFKEVPMNLYYETDKLLDSNLLVINIQPNEGVSLHLNAKKNTQGIETEPVQLSYSMSAQDKMNTVDAYENLLFDCLKGDATNFTHWEELKSTWKFVDAIQDEWNMVDPEFPNYESGTNGPLESDLLLARDGNHWWDDIQ

⊟Experimental data[edit | edit source]

  • experimentally validated: see SACOL1549
  • protein localization: see SACOL1549
  • quantitative data / protein copy number per cell: see SACOL1549
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://fungenwikiserver.biologie.uni-greifswald.de/aureowiki/index.php?title=SACOL_RS07890&oldid=75970"