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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS06540 [old locus tag: SACOL1281 ]
  • pan locus tag?: SAUPAN003563000
  • symbol: SACOL_RS06540
  • pan gene symbol?: rseP
  • synonym: eep
  • product: RIP metalloprotease RseP

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS06540 [old locus tag: SACOL1281 ]
  • symbol: SACOL_RS06540
  • product: RIP metalloprotease RseP
  • replicon: chromosome
  • strand: +
  • coordinates: 1290026..1291312
  • length: 1287
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (1290026..1291312) NCBI
  • BioCyc: SACOL_RS06540 BioCyc
  • MicrobesOnline: see SACOL1281

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    GTGAGCTATTTAGTTACAATAATTGCATTTATTATTGTTTTTGGTGTACTAGTAACTGTT
    CATGAATATGGCCATATGTTTTTTGCGAAAAGAGCAGGCATTATGTGTCCAGAATTTGCG
    ATCGGTATGGGGCCAAAAATTTTTAGTTTTAGAAAAAATGAAACACTTTACACTATTAGG
    TTATTGCCTGTTGGTGGATATGTTCGTATGGCAGGAGATGGCTTAGAAGAGCCACCAGTC
    GAGCCCGGTATGAACGTTAAAATTAAACTTAATGAAGAAAATGAAATAACACATATCATA
    TTAGATGATCATCATAAGTTTCAACAAATTGAAGCGATCGAAGTTAAAAAATGTGATTTT
    AAGGATGACTTATTCATAGAAGGTATCACTGCTTATGATAATGAAAGACATCATTTTAAA
    ATTGCTAGAAAGTCTTTCTTTGTTGAAAATGGTAGCTTAGTTCAAATTGCTCCGAGAGAC
    AGACAATTTGCACATAAAAAGCCATGGCCGAAATTTTTAACATTATTTGCGGGACCGTTA
    TTTAACTTTATATTAGCTTTAGTCCTATTTATTGGTCTTGCATATTATCAAGGCACGCCT
    ACGTCTACTGTAGAACAAGTCGCAGATAAGTATCCAGCTCAACAAGCAGGATTACAAAAA
    GGTGATAAGATCGTCCAAATTGGCAAATATAAAATATCTGAATTTGATGATGTTGATAAG
    GCGTTAGATAAAGTTAAAGATAATAAGACGACTGTTAAATTTGAACGTGATGGTAAAACA
    AAGTCAGTTGAATTAACACCTAAAAAGACTGAAAAAAAACTGACTAAAGTAAGTTCAGAG
    ACGAAGTATGTTCTCGGATTCCAACCAGCGAGTGAACATACACTTTTTAAACCAATTGTA
    TTCGGATTTAAAAGCTTTTTAATCGGTAGTACTTATATTTTTACAGCTGTAGTAGGTATG
    TTGGCTAGTATATTTACGGGCGGATTCTCATTTGATATGTTAAATGGTCCGGTTGGTATT
    TATCATAACGTCGACTCAGTTGTTAAAGCGGGTATCATTAGCTTAATTGGTTACACTGCG
    TTATTAAGTGTAAACTTAGGTATTATGAATTTAATTCCTATTCCTGCACTAGACGGTGGT
    CGTATTTTATTTGTTATATATGAAGCGATTTTCAGAAAACCAGTTAATAAAAAAGCGGAA
    ACAACGATTATTGCTATTGGTGCCATTTTCATGGTCGTTATAATGATATTAGTAACGTGG
    AATGATATTCGACGATATTTCTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1287

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS06540 [old locus tag: SACOL1281 ]
  • symbol: SACOL_RS06540
  • description: RIP metalloprotease RseP
  • length: 428
  • theoretical pI: 9.54429
  • theoretical MW: 48106.2
  • GRAVY: 0.175234

⊟Function[edit | edit source]

  • reaction:
    EC 3.4.24.-?  ExPASy
  • ⊞TIGRFAM:
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides RIP metalloprotease RseP (TIGR00054; EC 3.4.24.-; HMM-score: 287.4)
    and 7 more
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides peptidase Do (TIGR02037; EC 3.4.21.-; HMM-score: 37.8)
    Genetic information processing Protein fate Protein folding and stabilization peptidase Do (TIGR02037; EC 3.4.21.-; HMM-score: 37.8)
    Cellular processes Cellular processes Sporulation and germination stage IV sporulation protein B (TIGR02860; EC 3.4.21.116; HMM-score: 29.5)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides C-terminal processing peptidase (TIGR00225; EC 3.4.21.-; HMM-score: 27)
    Genetic information processing Protein fate Protein modification and repair C-terminal processing peptidase (TIGR00225; EC 3.4.21.-; HMM-score: 27)
    putative carboxyl-terminal-processing protease, deltaproteobacterial (TIGR03900; EC 3.4.21.-; HMM-score: 19.2)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type II secretion system protein C (TIGR01713; HMM-score: 15.9)
  • TheSEED: see SACOL1281
  • ⊞PFAM:
    Peptidase_MA (CL0126) Peptidase_M50; Peptidase family M50 (PF02163; HMM-score: 233.6)
    and 6 more
    PDZ-like (CL0466) PDZ_2; PDZ domain (PF13180; HMM-score: 40.5)
    PDZ_6; PDZ domain (PF17820; HMM-score: 31.6)
    PDZ; PDZ domain (PF00595; HMM-score: 22)
    PDZ_Tricorn; Tricorn protease PDZ domain (PF14685; HMM-score: 13.4)
    no clan defined DUF4663; Domain of unknown function (DUF4663) (PF15668; HMM-score: 11.9)
    Yip1 (CL0112) DUF1129; Protein of unknown function (DUF1129) (PF06570; HMM-score: 11.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors: Zn2+
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • ⊞DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9984
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0016
  • LocateP:
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.068841
    • TAT(Tat/SPI): 0.002422
    • LIPO(Sec/SPII): 0.004465
  • predicted transmembrane helices (TMHMM): 5

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIRLLPVGGYVRMAGDGLEEPPVEPGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDFKDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRDRQFAHKKPWPKFLTLFAGPLFNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGLQKGDKIVQIGKYKISEFDDVDKALDKVKDNKTTVKFERDGKTKSVELTPKKTEKKLTKVSSETKYVLGFQPASEHTLFKPIVFGFKSFLIGSTYIFTAVVGMLASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTALLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAETTIIAIGAIFMVVIMILVTWNDIRRYFL

⊟Experimental data[edit | edit source]

  • experimentally validated: see SACOL1281
  • protein localization: see SACOL1281
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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