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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2613 [new locus tag: SACOL_RS13670 ]
  • pan locus tag?: SAUPAN006281000
  • symbol: panD
  • pan gene symbol?: panD
  • synonym:
  • product: aspartate alpha-decarboxylase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL2613 [new locus tag: SACOL_RS13670 ]
  • symbol: panD
  • product: aspartate alpha-decarboxylase
  • replicon: chromosome
  • strand: -
  • coordinates: 2670366..2670749
  • length: 384
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    GTGATAAGAACAATGATGAATGCTAAAATTCATAGAGCAAGAGTGACTGAGTCAAATTTA
    AATTATGTAGGTAGCATTACGATTGATTCAGATATATTGGAAGCGGTAGACATCTTGCCA
    AATGAAAAAGTAGCCATCGTGAATAATAATAATGGTGCACGTTTTGAAACATACGTAATA
    GCTGGTGAAAGAGGTAGTGGTAAAATTTGTTTAAACGGTGCAGCGTCAAGACTTGTTGAA
    GTAGGCGATGTAGTCATAATCATGACTTATGCACAGTTGAATGAAGAAGAAATTAAAAAC
    CATGCACCTAAAGTAGCAGTAATGAATGAAGATAATGTCATTATTGAAATGATTCATGAA
    AAAGAAAATACGATAGTGTTATAA
    60
    120
    180
    240
    300
    360
    384

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL2613 [new locus tag: SACOL_RS13670 ]
  • symbol: PanD
  • description: aspartate alpha-decarboxylase
  • length: 127
  • theoretical pI: 4.75166
  • theoretical MW: 14050.1
  • GRAVY: 0.0023622

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 4.1.1.11?  ExPASy
    Aspartate 1-decarboxylase L-aspartate = beta-alanine + CO2
  • ⊞TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A aspartate 1-decarboxylase (TIGR00223; EC 4.1.1.11; HMM-score: 180)
    and 1 more
    crotonyl-CoA carboxylase/reductase (TIGR01751; EC 1.3.1.85; HMM-score: 16.8)
  • TheSEED  :
    • Aspartate 1-decarboxylase (EC 4.1.1.11)
    Cofactors, Vitamins, Prosthetic Groups, Pigments Coenzyme A Coenzyme A Biosynthesis  Aspartate 1-decarboxylase (EC 4.1.1.11)
  • ⊞PFAM:
    DPBB (CL0199) Asp_decarbox; Aspartate decarboxylase (PF02261; HMM-score: 173.9)
    and 1 more
    Beta_propeller (CL0186) PQQ_2; PQQ-like domain (PF13360; HMM-score: 11.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors: pyruvate
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9718
    • Cytoplasmic Membrane Score: 0.0009
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0271
  • ⊞LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005292
    • TAT(Tat/SPI): 0.000246
    • LIPO(Sec/SPII): 0.000518
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIRTMMNAKIHRARVTESNLNYVGSITIDSDILEAVDILPNEKVAIVNNNNGARFETYVIAGERGSGKICLNGAASRLVEVGDVVIIMTYAQLNEEEIKNHAPKVAVMNEDNVIIEMIHEKENTIVL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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